UniProtKB - G3UXL7 (G3UXL7_MOUSE)
Protein
Submitted name:
Transcription factor SOX-8
Gene
Sox8
Organism
Mus musculus (Mouse)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 1 – 65 | HMG boxPROSITE-ProRule annotationAdd BLAST | 65 |
GO - Molecular functioni
- DNA binding Source: UniProtKB-UniRule
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: InterPro
Keywordsi
Molecular function | DNA-bindingPROSITE-ProRule annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Transcription factor SOX-8Imported |
Gene namesi | Name:Sox8Imported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:98370, Sox8 |
Subcellular locationi
Nucleus
- nucleus Source: UniProtKB-UniRule
Keywords - Cellular componenti
NucleusPROSITE-ProRule annotationExpressioni
Gene expression databases
Bgeei | ENSMUSG00000024176, Expressed in primary visual cortex and 166 other tissues |
ExpressionAtlasi | G3UXL7, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 65 | HMG boxInterPro annotationAdd BLAST | 65 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 46 – 119 | DisorderedSequence analysisAdd BLAST | 74 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 46 – 85 | PolyampholyteSequence analysisAdd BLAST | 40 | |
Compositional biasi | 101 – 119 | PolyampholyteSequence analysisAdd BLAST | 19 |
Phylogenomic databases
GeneTreei | ENSGT00940000159920 |
HOGENOMi | CLU_2078422_0_0_1 |
Family and domain databases
Gene3Di | 1.10.30.10, 1 hit |
InterProi | View protein in InterPro IPR009071, HMG_box_dom IPR036910, HMG_box_dom_sf IPR031265, SOX-8 |
PANTHERi | PTHR45803:SF2, PTHR45803:SF2, 1 hit |
Pfami | View protein in Pfam PF00505, HMG_box, 1 hit |
SMARTi | View protein in SMART SM00398, HMG, 1 hit |
SUPFAMi | SSF47095, SSF47095, 1 hit |
PROSITEi | View protein in PROSITE PS50118, HMG_BOX_2, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
G3UXL7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
XNAFMVWAQA ARRKLADQYP HLHNAELSKT LGKLWRLLSE SEKRPFVEEA
60 70 80 90 100
ERLRVQHKKD HPDYKYQPRR RKSVKTGRSD SDSGTELGHH PGGPMYKADA
110
VLGEAHHHSD HHTGGLQDP
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ04886 | SOX8_MOUSE | Transcription factor SOX-8 | Sox8 Sox-8 | 464 | Annotation score: | ||
G3UWS3 | G3UWS3_MOUSE | Transcription factor SOX-8 | Sox8 | 221 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC154418 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENSMUST00000174560; ENSMUSP00000133742; ENSMUSG00000024176 |
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC154418 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
Proteomic databases
MaxQBi | G3UXL7 |
Protocols and materials databases
Antibodypediai | 9438, 338 antibodies |
Genome annotation databases
Ensembli | ENSMUST00000174560; ENSMUSP00000133742; ENSMUSG00000024176 |
Organism-specific databases
MGIi | MGI:98370, Sox8 |
Phylogenomic databases
GeneTreei | ENSGT00940000159920 |
HOGENOMi | CLU_2078422_0_0_1 |
Miscellaneous databases
ChiTaRSi | Sox8, mouse |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000024176, Expressed in primary visual cortex and 166 other tissues |
ExpressionAtlasi | G3UXL7, baseline and differential |
Family and domain databases
Gene3Di | 1.10.30.10, 1 hit |
InterProi | View protein in InterPro IPR009071, HMG_box_dom IPR036910, HMG_box_dom_sf IPR031265, SOX-8 |
PANTHERi | PTHR45803:SF2, PTHR45803:SF2, 1 hit |
Pfami | View protein in Pfam PF00505, HMG_box, 1 hit |
SMARTi | View protein in SMART SM00398, HMG, 1 hit |
SUPFAMi | SSF47095, SSF47095, 1 hit |
PROSITEi | View protein in PROSITE PS50118, HMG_BOX_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | G3UXL7_MOUSE | |
Accessioni | G3UXL7Primary (citable) accession number: G3UXL7 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 16, 2011 |
Last sequence update: | November 16, 2011 | |
Last modified: | October 7, 2020 | |
This is version 58 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |