We will be switching to the new UniProt website on Tuesday, June 28. Please explore and share your feedback.
Take me to UniProt BETA
UniProtKB - G3UWZ0 (G3UWZ0_MOUSE)
Protein
Submitted name:
Bromodomain adjacent to zinc finger domain protein 1A
Gene
Baz1a
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- metal ion binding Source: UniProtKB-KW
GO - Biological processi
- chromatin remodeling Source: InterPro
Keywordsi
Biological process | Transcription, Transcription regulationARBA annotation |
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: Bromodomain adjacent to zinc finger domain protein 1A |
Gene namesi | Name:Baz1aImported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:1309478, Baz1a |
VEuPathDBi | HostDB:ENSMUSG00000035021 |
Subcellular locationi
Nucleus
- Nucleus PROSITE-ProRule annotation
Nucleus
- nucleus Source: UniProtKB-SubCell
Keywords - Cellular componenti
NucleusPROSITE-ProRule annotationARBA annotationPTM / Processingi
Keywords - PTMi
PhosphoproteinARBA annotationProteomic databases
EPDi | G3UWZ0 |
jPOSTi | G3UWZ0 |
MaxQBi | G3UWZ0 |
PeptideAtlasi | G3UWZ0 |
PRIDEi | G3UWZ0 |
ProteomicsDBi | 351334 |
PTM databases
iPTMneti | G3UWZ0 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000035021, Expressed in blastocyst and 230 other tissues |
ExpressionAtlasi | G3UWZ0, baseline and differential |
Genevisiblei | G3UWZ0, MM |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 22 – 128 | WACInterPro annotationAdd BLAST | 107 | |
Domaini | 422 – 487 | DDTInterPro annotationAdd BLAST | 66 | |
Domaini | 1146 – 1196 | PHD-typeInterPro annotationAdd BLAST | 51 | |
Domaini | 1442 – 1512 | BromoInterPro annotationAdd BLAST | 71 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 651 – 749 | DisorderedSequence analysisAdd BLAST | 99 | |
Regioni | 840 – 871 | DisorderedSequence analysisAdd BLAST | 32 | |
Regioni | 941 – 966 | DisorderedSequence analysisAdd BLAST | 26 | |
Regioni | 1200 – 1426 | DisorderedSequence analysisAdd BLAST | 227 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 324 – 394 | Sequence analysisAdd BLAST | 71 | |
Coiled coili | 770 – 791 | Sequence analysisAdd BLAST | 22 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 651 – 724 | Basic and acidic residuesSequence analysisAdd BLAST | 74 | |
Compositional biasi | 948 – 966 | Polar residuesSequence analysisAdd BLAST | 19 | |
Compositional biasi | 1214 – 1253 | Acidic residuesSequence analysisAdd BLAST | 40 | |
Compositional biasi | 1278 – 1339 | Polar residuesSequence analysisAdd BLAST | 62 | |
Compositional biasi | 1348 – 1364 | Basic and acidic residuesSequence analysisAdd BLAST | 17 | |
Compositional biasi | 1365 – 1395 | Polar residuesSequence analysisAdd BLAST | 31 |
Keywords - Domaini
BromodomainPROSITE-ProRule annotationARBA annotation, Coiled coilSequence analysisARBA annotation, Zinc-fingerPROSITE-ProRule annotationARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000158135 |
HOGENOMi | CLU_002479_1_0_1 |
OMAi | CEATGKD |
OrthoDBi | 858930at2759 |
Family and domain databases
CDDi | cd05504, Bromo_Acf1_like, 1 hit |
Gene3Di | 1.20.920.10, 1 hit 3.30.40.10, 1 hit |
InterProi | View protein in InterPro IPR037325, Acf1_Bromo IPR001487, Bromodomain IPR036427, Bromodomain-like_sf IPR018359, Bromodomain_CS IPR018501, DDT_dom IPR028942, WHIM1_dom IPR028941, WHIM2_dom IPR013136, WSTF_Acf1_Cbp146 IPR019786, Zinc_finger_PHD-type_CS IPR011011, Znf_FYVE_PHD IPR001965, Znf_PHD IPR019787, Znf_PHD-finger IPR013083, Znf_RING/FYVE/PHD |
Pfami | View protein in Pfam PF00439, Bromodomain, 1 hit PF02791, DDT, 1 hit PF00628, PHD, 1 hit PF10537, WAC_Acf1_DNA_bd, 1 hit PF15612, WHIM1, 1 hit PF15613, WSD, 1 hit |
PRINTSi | PR00503, BROMODOMAIN |
SMARTi | View protein in SMART SM00297, BROMO, 1 hit SM00571, DDT, 1 hit SM00249, PHD, 1 hit |
SUPFAMi | SSF47370, SSF47370, 1 hit SSF57903, SSF57903, 1 hit |
PROSITEi | View protein in PROSITE PS00633, BROMODOMAIN_1, 1 hit PS50014, BROMODOMAIN_2, 1 hit PS50827, DDT, 1 hit PS51136, WAC, 1 hit PS01359, ZF_PHD_1, 1 hit PS50016, ZF_PHD_2, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All
G3UWZ0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPLLHRKPFV RQKPPGDLRP DEEVFYCKVT NEIFRHYDDF FERTILCNSL
60 70 80 90 100
VWSCAVTGRP GLTYQEALES ERKARQNLQS FPEPLIIPVL YLTNLTRRSR
110 120 130 140 150
LHEICDDIFA YVKDRYFVEE TVEVIRNNGT RLQCRILEVL PPLHQNGFAN
160 170 180 190 200
GHLSSADGET IVISDSDDSE TQSSSFHHGK KKDAIDPLLF RYRVQPTKKE
210 220 230 240 250
MYESAVVKAT QISRRKHLFS RDKLKLFLKQ HCEAQDGVIK IKASSFSAYN
260 270 280 290 300
IAEQDFSYFF PDDPPTFIFS PANRRRGRPP KRISFGQEDS IASKQTAARY
310 320 330 340 350
RNKAIKERDK LLKQEEMRAL AFEKAKLKRE RADALEARKR EKEDKEKKRE
360 370 380 390 400
ELKKMVEEER LKKKEEKERL KIEREKEREK LREEKRKYME YLKQWSKPRE
410 420 430 440 450
DMECDDLKEL PEPTPVKTRL PPEVFGDALM VLEFLNAFGE LFDLQDEFPE
460 470 480 490 500
GVTLEVLEEA LVGNDSEGPL CELLFFFLTA IFQAMAEEEE EVAKEQITDA
510 520 530 540 550
DTKDLTEALD EDADPTKSAL SAVAALAAAW PQLHQGCSLK SLDLDSCTLS
560 570 580 590 600
EILRLHILAS GADVTSANAK YRYQKRGGFD ATDDACMELR LSNPSLVKKL
610 620 630 640 650
SSTSVYDLTP GEKMKILHAL CGKLLTLVST RDFIEDYVDV LRQAKQEFRE
660 670 680 690 700
LKAEQHRKER EATAARIRRR KEEKLKEQEQ KMKEKQEKLK EDEQRNSAAV
710 720 730 740 750
PGEEEREDFD TSTENKNIEQ KDLDPDVVTE DEDDPGSHKR SRRGKVGQTA
760 770 780 790 800
VKQCIKQEEM NYCIKQEPLS ADAEEALRQE QQQKEKELLD KIQSAIACTN
810 820 830 840 850
IFPLGRDRLY RRYWIFPSIP GLFIEEDYSG LTEDMLLPRP SSFHNNAQPR
860 870 880 890 900
DPQVSIKTEE SFLSESTSSL DQGPFDDSVL LPKPVHKPNR WCFYSSCAQL
910 920 930 940 950
DQLIDALNSR GHRESALKET LLQEKSRICA QLAHFSEEKF HFSDKPQADS
960 970 980 990 1000
KPVSSRGRSS GACDISQMSA ERQLELRLRD FLLDIEDRIY QGTLGAIKVT
1010 1020 1030 1040 1050
DRQVWRSALE NGRYELLSEE SKENGVIKTV NEDVEEMEME QARVIVRDRL
1060 1070 1080 1090 1100
LGIKTETPST ISTSASTPQS VSNVVHYLAL ALFQIEQGIE RRFLKAPLDG
1110 1120 1130 1140 1150
NDSGRSYKTV LDRWRESLLS SASLSQVFLH LSTLDRSVMW SKSILNARCK
1160 1170 1180 1190 1200
ICRKKGDAEN MVLCDGCDRG HHTYCVRPKL KAVPDGDWFC PECRPKQRSR
1210 1220 1230 1240 1250
RLSSRQRPSL ESDEEMEEGM EDDDDEVDDD DEEGQSEEEE YEVEQDEEDS
1260 1270 1280 1290 1300
DDDEALSPPK RGRPQVRLPI KTKGRFGPSF PSRSQRQDPG RYPSRSQQST
1310 1320 1330 1340 1350
PKNTAKSASK NLRKTRSAPP TETRSLRVGS RSTRHSPSAL QDVFVELLSP
1360 1370 1380 1390 1400
HSKRRGRKGA DHTPEHSPSF TNFRVSTSRS SRQLIPLNTA ESLSLQHSES
1410 1420 1430 1440 1450
KRRGRKRQST ESSPVPLNRR SSGRQGGVHE LSAFEQLVVE LVRHDDSWPF
1460 1470 1480 1490 1500
LKLVSKIQVP DYYDIIKKPI ALNIIREKVN KCEYKLASEF IDDIELMFSN
1510 1520 1530 1540 1550
CFEYNPRNTS EAKAGTRLQA FFHIQAQKLG LHVSPSTVDQ VSTPLAAKKS
RI
Computationally mapped potential isoform sequencesi
There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketO88379 | BAZ1A_MOUSE | Bromodomain adjacent to zinc finger... | Baz1a Cbp146 | 1,555 | Annotation score: | ||
G3UXR5 | G3UXR5_MOUSE | Bromodomain adjacent to zinc finger... | Baz1a | 86 | Annotation score: | ||
G3UZ82 | G3UZ82_MOUSE | Bromodomain adjacent to zinc finger... | Baz1a | 172 | Annotation score: | ||
G3UZD1 | G3UZD1_MOUSE | Bromodomain adjacent to zinc finger... | Baz1a | 81 | Annotation score: | ||
G3UWK3 | G3UWK3_MOUSE | Bromodomain adjacent to zinc finger... | Baz1a | 79 | Annotation score: | ||
G3UYS9 | G3UYS9_MOUSE | Bromodomain adjacent to zinc finger... | Baz1a | 91 | Annotation score: |
Sequence databases
RefSeqi | NP_038843.2, NM_013815.2 XP_006515733.1, XM_006515670.3 |
Genome annotation databases
Ensembli | ENSMUST00000173433.8; ENSMUSP00000133478.2; ENSMUSG00000035021.14 |
GeneIDi | 217578 |
KEGGi | mmu:217578 |
UCSCi | uc007nnz.2, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
RefSeqi | NP_038843.2, NM_013815.2 XP_006515733.1, XM_006515670.3 |
3D structure databases
SMRi | G3UWZ0 |
ModBasei | Search... |
PTM databases
iPTMneti | G3UWZ0 |
Proteomic databases
EPDi | G3UWZ0 |
jPOSTi | G3UWZ0 |
MaxQBi | G3UWZ0 |
PeptideAtlasi | G3UWZ0 |
PRIDEi | G3UWZ0 |
ProteomicsDBi | 351334 |
Protocols and materials databases
Antibodypediai | 113, 131 antibodies from 24 providers |
Genome annotation databases
Ensembli | ENSMUST00000173433.8; ENSMUSP00000133478.2; ENSMUSG00000035021.14 |
GeneIDi | 217578 |
KEGGi | mmu:217578 |
UCSCi | uc007nnz.2, mouse |
Organism-specific databases
CTDi | 11177 |
MGIi | MGI:1309478, Baz1a |
VEuPathDBi | HostDB:ENSMUSG00000035021 |
Phylogenomic databases
GeneTreei | ENSGT00940000158135 |
HOGENOMi | CLU_002479_1_0_1 |
OMAi | CEATGKD |
OrthoDBi | 858930at2759 |
Miscellaneous databases
BioGRID-ORCSi | 217578, 6 hits in 77 CRISPR screens |
ChiTaRSi | Baz1a, mouse |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000035021, Expressed in blastocyst and 230 other tissues |
ExpressionAtlasi | G3UWZ0, baseline and differential |
Genevisiblei | G3UWZ0, MM |
Family and domain databases
CDDi | cd05504, Bromo_Acf1_like, 1 hit |
Gene3Di | 1.20.920.10, 1 hit 3.30.40.10, 1 hit |
InterProi | View protein in InterPro IPR037325, Acf1_Bromo IPR001487, Bromodomain IPR036427, Bromodomain-like_sf IPR018359, Bromodomain_CS IPR018501, DDT_dom IPR028942, WHIM1_dom IPR028941, WHIM2_dom IPR013136, WSTF_Acf1_Cbp146 IPR019786, Zinc_finger_PHD-type_CS IPR011011, Znf_FYVE_PHD IPR001965, Znf_PHD IPR019787, Znf_PHD-finger IPR013083, Znf_RING/FYVE/PHD |
Pfami | View protein in Pfam PF00439, Bromodomain, 1 hit PF02791, DDT, 1 hit PF00628, PHD, 1 hit PF10537, WAC_Acf1_DNA_bd, 1 hit PF15612, WHIM1, 1 hit PF15613, WSD, 1 hit |
PRINTSi | PR00503, BROMODOMAIN |
SMARTi | View protein in SMART SM00297, BROMO, 1 hit SM00571, DDT, 1 hit SM00249, PHD, 1 hit |
SUPFAMi | SSF47370, SSF47370, 1 hit SSF57903, SSF57903, 1 hit |
PROSITEi | View protein in PROSITE PS00633, BROMODOMAIN_1, 1 hit PS50014, BROMODOMAIN_2, 1 hit PS50827, DDT, 1 hit PS51136, WAC, 1 hit PS01359, ZF_PHD_1, 1 hit PS50016, ZF_PHD_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | G3UWZ0_MOUSE | |
Accessioni | G3UWZ0Primary (citable) accession number: G3UWZ0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 16, 2011 |
Last sequence update: | November 16, 2011 | |
Last modified: | May 25, 2022 | |
This is version 77 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |