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Entry version 62 (02 Dec 2020)
Sequence version 1 (16 Nov 2011)
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Protein
Submitted name:

Zinc finger protein 407

Gene

Zfp407

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Zinc finger protein 407Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Zfp407Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 18

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2685179, Zfp407

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

NucleusARBA annotation

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
G3UVV3

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
G3UVV3

MaxQB - The MaxQuant DataBase

More...
MaxQBi
G3UVV3

PeptideAtlas

More...
PeptideAtlasi
G3UVV3

PRoteomics IDEntifications database

More...
PRIDEi
G3UVV3

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
G3UVV3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000048410, Expressed in dorsal pancreas and 256 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
G3UVV3, baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000118361

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
G3UVV3

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156446

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_002134_0_0_1

Identification of Orthologs from Complete Genome Data

More...
OMAi
DNKCLHC

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

TreeFam database of animal gene trees

More...
TreeFami
TF350895

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003604, Matrin/U1-like-C_Znf_C2H2
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00096, zf-C2H2, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00355, ZnF_C2H2, 24 hits
SM00451, ZnF_U1, 7 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57667, SSF57667, 5 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 7 hits
PS50157, ZINC_FINGER_C2H2_2, 8 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

G3UVV3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDSENKHDND EDESVKGAKD PRSVSSRDDS SEPVSDDMAN VSENFTSKRV
60 70 80 90 100
FSESSNSDGV AAEEYRSERA SKRLRTEALE PETREQGACG LGTVEANVHL
110 120 130 140 150
AEMGKEAFPA NCSEGGSALP SVFSPSCDFS TSNILPLKVD EVKKPAREMV
160 170 180 190 200
SLVPERHNPF PPEERSISCS FGSVETGLRC GVCGCSFSSC SALEKHVECH
210 220 230 240 250
VEEGKERTCC HCSHRAESSS SPHEHVRHTH GPQKVFSCDL CGFQCAEENL
260 270 280 290 300
LNAHYLGKTH LRRQNLAARG GFVQILTKPS FPKKACVMGT KNVRTKPRAS
310 320 330 340 350
KPIAKTGDSR VVPSTGNDFK DCRGAPSEDS AGGSELLVEM VPSRKISSGK
360 370 380 390 400
AHVVEENVSF GVAQNPENQN KQLGGLVSSE GLLNKPESTK NALQMAHVSI
410 420 430 440 450
STTSRPRSER NLLVLGNSFR RRSGTFTLKG QAKKRFNLLG INKRGTNETQ
460 470 480 490 500
RMYMKHFRTQ MKTNAQPVLE QVEMSKDVQS LCVTTSDNPE VMQDKTAFCL
510 520 530 540 550
SGSTRLGSLP VKPADHQLSV QCTCTECGQI AANKTDFEVH VKQCHGREMQ
560 570 580 590 600
FHCQTCDFSS PSRRDLEEHV HSNQHQHMTP VLSCQCCSFI SLNETGLRDH
610 620 630 640 650
MKEKHGMGFF CTSCNLFLSE KDVEEHRATE SHNSLVVQPK TASSLSGDSV
660 670 680 690 700
LPFSTVESEN PADSREDSGK AAQEGPAESR ASHGTEARHS SKPQFQCKKC
710 720 730 740 750
FYKTRSSTVL TRHIKLRHGQ DYHFLCKACN LYSLSKEGME KHIKRSKHLE
760 770 780 790 800
NAKKNNIGLS FEECIERVCI GANDKKEESS VSGSGRPEGH VGVQSQEHSQ
810 820 830 840 850
REQSMLTPKE LPQSGVITKE DELGLATTPK RGRPKGSISR TCSHCGLLAS
860 870 880 890 900
SITNLTVHIR RKHSHQYSYL CKVCKYYTVT KGDMERHCAT KKHKGRVEIE
910 920 930 940 950
ANGKQSSDIV VGPEGGNLEA CKDSTSLAVT VSDAQASKPA KSDTRTLETP
960 970 980 990 1000
GVGIGNAGDA EAGSVFPSGD GELSSQLSDK KGQLSLETED LLQLDDACSQ
1010 1020 1030 1040 1050
REVAGSSDNK CLQCEFSAHS AASLELHVKR KHTKEFQFYC MACDYYAVTR
1060 1070 1080 1090 1100
REMTRHAATE KHRMKRQSYL SASSVEAGSS EISKNITIPE EEHSHNSEEF
1110 1120 1130 1140 1150
QIHPHQSSGT LQCRNPADCS ILDDNTNLGM SKVLCAPDSV TVVTEQESNF
1160 1170 1180 1190 1200
SEGHSFCETL QQPLVKDKSM KPREIVSPNT PSNLSLPGCL QSENLASSAV
1210 1220 1230 1240 1250
DCETAKKNRD VLDAVGDRST PCEDEGGSVD DSEEKILDKS PCPGDPDGGH
1260 1270 1280 1290 1300
SAESTSSVVM KIPREQLDLD GGGQNKVGCE QTSEDLKDVQ ANPILENKEI
1310 1320 1330 1340 1350
LINSQEEAEV ILEEDAPTSN GTADSNDVYE TIISIDDKGQ TMYSFGRFDS
1360 1370 1380 1390 1400
SIIRIKTEDG ELVEQPEEGL TATGGRVSEL PLKDCAQGLK KKKVEGGSFG
1410 1420 1430 1440 1450
ESTRIRCDDC GFLADGLSGL NVHIAMKHPT KEKHFHCLLC GKSFYTESNL
1460 1470 1480 1490 1500
HQHLASAGHM RNEQASVEEL PEGGATFKCV KCTEPFDSEQ NLFLHIKGQH
1510 1520 1530 1540 1550
EELLREVNKY IVEDTEQINR EREENQGNVC KYCGKMCRSS NSMAFLAHIR
1560 1570 1580 1590 1600
THTGSKPFKC KICHFATAQL GDARNHVKRH LGMREYKCHV CGVAFVMKKH
1610 1620 1630 1640 1650
LNTHLLGKHG VGTPKERKFT CHLCDRSFTE KWALNNHMKL HTGEKPFKCT
1660 1670 1680 1690 1700
WPTCHYSFLT ASAMKDHYRT HTGEKSFLCD LCGFAGGTRH ALTKHRRQHT
1710 1720 1730 1740 1750
GEKPFKCDEC NFASTTQSHL TRHKRVHTGE KPYRCPWCDY RSNCAENIRK
1760 1770 1780 1790 1800
HILHTGKHEG VKMYNCPKCD YGTNVPVEFR NHLKEQHPDI ENPDLAYLHA
1810 1820 1830 1840 1850
GIVSKSYECR LKGQGATFVE TDSPFTAATL AEESPVKERS LRSSKRQAAS
1860 1870 1880 1890 1900
PEQVQQVIII QGYDGEFALD ASVEETAAAT LQTLAMAGQV ARVVHITEHG
1910 1920 1930 1940 1950
QVIATSQNGS HVGSVVPGPI LPEQLADGTT QVVVMGGSME SHSVDEALSP
1960 1970 1980 1990 2000
GAAVIQQVTK QEVLSLSEAG VPPSDNSSAL DALLCAVTEL GEVEGRVGHE
2010 2020 2030 2040 2050
EKGRPSHKDV LIQLPSQEAA QAHAKAEATE AQLFQDVEES PASMEVLTQV
2060 2070 2080 2090 2100
VRPSTIITSQ ERAQVAFKKM VQGVLQFAVC DTAAASQLIK DGVTQVIVNE
2110 2120 2130 2140 2150
EGAVHMVAGE GSQFIMQEAE THGLRVPAEH MDLVESEGEI SQIIVTEELV
2160 2170 2180 2190 2200
QAMVRESNSS FPEGATHYIV TELPPGVQED TGVYSHTVIE TASSPEILQA
2210 2220 2230 2240
GAALSAEAVG SSSTEQLTSM VIYTQDGSPA ATVIQSQREN SELQEA
Length:2,246
Mass (Da):245,963
Last modified:November 16, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAFA331998912774F
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
S4R2G4S4R2G4_MOUSE
Zinc finger protein 407
Zfp407
72Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC124012 Genomic DNA No translation available.
AC124187 Genomic DNA No translation available.
AC126021 Genomic DNA No translation available.
AC149591 Genomic DNA No translation available.
AC152060 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
NP_001028513.2, NM_001033341.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000125763; ENSMUSP00000118361; ENSMUSG00000048410

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
240476

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:240476

UCSC genome browser

More...
UCSCi
uc008fuo.2, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124012 Genomic DNA No translation available.
AC124187 Genomic DNA No translation available.
AC126021 Genomic DNA No translation available.
AC149591 Genomic DNA No translation available.
AC152060 Genomic DNA No translation available.
RefSeqiNP_001028513.2, NM_001033341.2

3D structure databases

SMRiG3UVV3
ModBaseiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000118361

PTM databases

iPTMnetiG3UVV3

Proteomic databases

EPDiG3UVV3
jPOSTiG3UVV3
MaxQBiG3UVV3
PeptideAtlasiG3UVV3
PRIDEiG3UVV3

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
23353, 47 antibodies

Genome annotation databases

EnsembliENSMUST00000125763; ENSMUSP00000118361; ENSMUSG00000048410
GeneIDi240476
KEGGimmu:240476
UCSCiuc008fuo.2, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
240476
MGIiMGI:2685179, Zfp407

Phylogenomic databases

eggNOGiKOG1721, Eukaryota
GeneTreeiENSGT00940000156446
HOGENOMiCLU_002134_0_0_1
OMAiDNKCLHC
OrthoDBi1318335at2759
TreeFamiTF350895

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
240476, 4 hits in 19 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Zfp407, mouse

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000048410, Expressed in dorsal pancreas and 256 other tissues
ExpressionAtlasiG3UVV3, baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR003604, Matrin/U1-like-C_Znf_C2H2
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF00096, zf-C2H2, 2 hits
SMARTiView protein in SMART
SM00355, ZnF_C2H2, 24 hits
SM00451, ZnF_U1, 7 hits
SUPFAMiSSF57667, SSF57667, 5 hits
PROSITEiView protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 7 hits
PS50157, ZINC_FINGER_C2H2_2, 8 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG3UVV3_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G3UVV3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: December 2, 2020
This is version 62 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health

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