Myocyte enhancer factor 2D

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functionⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• activating transcription factor binding Source: Ensembl
• DNA-binding transcription activator activity, RNA polymerase II-specific Source: Ensembl
• histone deacetylase binding Source: Ensembl
• protein heterodimerization activity Source: Ensembl
• protein homodimerization activity Source: Ensembl
• RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: Ensembl

GO - Biological processⁱ

• adult heart development Source: Ensembl
• chondrocyte differentiation Source: Ensembl
• endochondral ossification Source: Ensembl
• osteoblast differentiation Source: Ensembl
• positive regulation of vascular associated smooth muscle cell proliferation Source: Ensembl
• skeletal muscle cell differentiation Source: Ensembl

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsⁱ

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

Keywords - Cellular componentⁱ

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactionⁱ

GO - Molecular functionⁱ

• activating transcription factor binding Source: Ensembl
• histone deacetylase binding Source: Ensembl
• protein heterodimerization activity Source: Ensembl
• protein homodimerization activity Source: Ensembl

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Domains and Repeats

Region

Compositional bias

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)ⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

        10         20         30         40         50
MGRKKIQIQR ITDERNRQVT FTKRKFGLMK KAYELSVLCD CEIALIIFNH 
        60         70         80         90        100
SNKLFQYAST DMDKVLLKYT EYNEPHESRT NADIIETLRK KGFNGCDSPE 
       110        120        130        140        150
PDGEDSLEQS PLLEDKYRRA SEELDGLFRR YGSAVPAPNF AMPVTVPVSN 
       160        170        180        190        200
QSSLQFSNPS SSLVTPSLVT SSLTDPRLLS PQQPALQRNS VSPGLPQRPA 
       210        220        230        240        250
SAGAMLGGDL SSANGACPSP VGNGYVSARA SPGLLPVANG NSLNKVIPAK 
       260        270        280        290        300
SPPPPTHSAQ LGAPSRKPDL RVITSQGGKG LMHHLTEDHL DLNNAQRLGV 
       310        320        330        340        350
SQSTHSLTTP VVSVATPSLL SQGLPFSSMP TAYNTDYQLT SAELSSLPAF 
       360        370        380        390        400
SSPGGLSLGN VTAWQQPQQP QQPPQPQPPQ PQPQPQQPQQ PQPPQQPPQQ 
       410        420        430        440        450
QPHLVPVSLG NLIPGSPLPH VGAALTVTTH PHISIKSEPV SPSRERSPAP 
       460        470        480        490        500
PPPAVFPAAR AEPGDGLSSP AGGSYETGDR DDGRGDFGPT LGLLRPAPEQ 
       510 
EAEGSAVKRM RLDTWVL                                     

Genome annotation databases

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ

• 90% Identity
• 50% Identity

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

3D structure databases

Protein-protein interaction databases

Genome annotation databases

Phylogenomic databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

Keywords - Technical termⁱ