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Protein
Submitted name:

BRCA1 interacting protein C-terminal helicase 1

Gene

BRIP1

Organism
Loxodonta africana (African elephant)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Catalytic activityi

ATP + H2O = ADP + phosphate.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHelicaseSAAS annotation, Hydrolase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
BRCA1 interacting protein C-terminal helicase 1Imported
Gene namesi
Name:BRIP1Imported
OrganismiLoxodonta africana (African elephant)Imported
Taxonomic identifieri9785 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaAfrotheriaProboscideaElephantidaeLoxodonta
Proteomesi
  • UP000007646 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi9785.ENSLAFP00000012470

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 447Helicase ATP-bindingInterPro annotationAdd BLAST437

Phylogenomic databases

eggNOGiKOG1132 Eukaryota
COG1199 LUCA
GeneTreeiENSGT00530000063199
InParanoidiG3TE28
OMAiTNNDMNQ
OrthoDBiEOG091G00LK
TreeFamiTF329449

Family and domain databases

InterProiView protein in InterPro
IPR006555 ATP-dep_Helicase_C
IPR010614 DEAD_2
IPR014013 Helic_SF1/SF2_ATP-bd_DinG/Rad3
IPR006554 Helicase-like_DEXD_c2
IPR027417 P-loop_NTPase
IPR013020 Rad3/Chl1-like
PfamiView protein in Pfam
PF06733 DEAD_2, 1 hit
PF13307 Helicase_C_2, 1 hit
SMARTiView protein in SMART
SM00488 DEXDc2, 1 hit
SM00491 HELICc2, 1 hit
SUPFAMiSSF52540 SSF52540, 6 hits
TIGRFAMsiTIGR00604 rad3, 1 hit
PROSITEiView protein in PROSITE
PS51193 HELICASE_ATP_BIND_2, 1 hit

Sequencei

Sequence statusi: Complete.

G3TE28-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSVWSEYTI GGVKINFPCK AYPSQLAMMN CIVRGLNSKQ HCLLESPTGS
60 70 80 90 100
GKSLALLCSA LAWQQSLSGK PVDEGLSKKA EVPPSCSCTC HSKNFPNNDI
110 120 130 140 150
MNPGTSHHFG SPSTPPSERN ITSSTCQDSP EKNTLAAKLS AKKQASVCRN
160 170 180 190 200
ENDDFQVDKK RIRLLETTQQ IRKRHSFEKE VHHLDAKVAS GKAVKLNSPS
210 220 230 240 250
GTTNSFSLQS DSFDNPPGHC SRCCCSPKQG NSQDSSNAIK KDHGGKSKIP
260 270 280 290 300
KIYFGTRTHK QIAQITRELR RTAYSGVPMT ILSSRDHTCV HPEAVGNFNR
310 320 330 340 350
KEKCMELLDG KNGKSCYFYH GVHKIRDQHT LQTLQGMHEM YKQIELLKIY
360 370 380 390 400
SKISICYSIR QKTTQLLLAF CFFKAYIQDE QISLQMDINL KEQVVILDEA
410 420 430 440 450
HNIEDCARES ASYSVTEVQL WFARDELDSM VNNNIRKKDH DPLRAVCYSL
460 470 480 490 500
IHWLEAHSEH LVERHYESSC KIWSGNEMIF HLHKMGITSA TFPILQGHFS
510 520 530 540 550
AVLQKEEKVS SVHGKEEARE IPVISASTQV MLKGLFMVLD YLFRQNSRFA
560 570 580 590 600
DDYKVAIQQT YSWINQTDTS DRNEFFALPK NKKRSRQKTA VHVLNFWCLN
610 620 630 640 650
PAVAFSDIDE KVQTIVLTSG TLSPMKSFSS ELGVTFTIQL EANHVINNSQ
660 670 680 690 700
VWVGTIGSGP TGRNLCATFQ HTETFEFQDE VGALLLSVCQ TVSQGILCFL
710 720 730 740 750
PSYKLLEKLK ERWHSTGLWR NLELVKTVIV EPQGGDKTEF DELLQVYYDA
760 770 780 790 800
VKYRGEKDGA LLVAVCRGKV SEGLDFSDDN ARAVITVGIP FPNVKDLQVE
810 820 830 840 850
LKRQYNDQHS KLRGLLPGRQ WYEIQAYRAL NQALGRCIRH KNDWGALILV
860 870 880 890 900
DDRFRSNPSR YISGLSKWVR QQIQHHSTFE SALESLTEFS KKHLKVIDVS
910 920 930 940 950
IQDRKSIQDS ECILEVARLK DSTPTSLLEA ESHLSPENPW EDDIKMCVQE
960 970 980 990 1000
RQCPKMITKN SSPPNGTISR KEKDDTVLSE ESVQAMKRGK TVISRSTSPT
1010 1020 1030 1040 1050
FSKQAKRVSW PSFHSSGQYC TGKILTAAPE LRTSEDCTSS TSTIKIEKME
1060 1070 1080 1090 1100
SRPVLPLTDK CESSSLTVNI SLEPCPQSEI IVAPIKTDFA LTEKDHPKRL
1110 1120 1130 1140 1150
LCCEKTLNPD TEMSFVSEET KLSTSNRSFE TEAEDESVYF TPELYDPIDI
1160 1170 1180
DEKKNEPVET DGISTLADNS NYILAEDVFE DETMKGED
Length:1,188
Mass (Da):133,996
Last modified:November 16, 2011 - v1
Checksum:iBC9A96C11291527D
GO

Genome annotation databases

EnsembliENSLAFT00000014887; ENSLAFP00000012470; ENSLAFG00000014884

Similar proteinsi

Entry informationi

Entry nameiG3TE28_LOXAF
AccessioniPrimary (citable) accession number: G3TE28
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: March 28, 2018
This is version 39 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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