G protein subunit alpha 12

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functionⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• G-protein beta/gamma-subunit complex binding Source: InterPro
• G protein-coupled receptor binding Source: InterPro
• GTPase activity Source: InterPro
• guanyl nucleotide binding Source: InterPro

GO - Biological processⁱ

• cell differentiation Source: Ensembl
• embryonic digit morphogenesis Source: Ensembl
• G protein-coupled receptor signaling pathway Source: InterPro
• in utero embryonic development Source: Ensembl
• regulation of cell shape Source: Ensembl
• regulation of fibroblast migration Source: Ensembl
• regulation of proteasomal ubiquitin-dependent protein catabolic process Source: Ensembl
• regulation of TOR signaling Source: Ensembl
• Rho protein signal transduction Source: Ensembl

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsⁱ

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactionⁱ

GO - Molecular functionⁱ

• G protein-coupled receptor binding Source: InterPro

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Coiled coil

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesⁱ

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)ⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

        10         20         30         40         50
MSAVVRTLSR CLLPAEAGGG ARDAEREARR RSRDIDALLA RERRAVRRLV 
        60         70         80         90        100
KILLLGAGES GKSTFLKQMR IIHGREFDQK ALLEFRDTIF DNILKGSRVL 
       110        120        130        140        150
VDARDKLGIP WQYSENEKHG MFLMAFENKA GLPLEPATFQ LYVPALSALW 
       160        170        180        190        200
KDSGIREAFS RRSEFQLGES VKYFLDNLDR IGQLNYFPSK QDILLARKAT 
       210        220        230        240        250
KGIVEHDFVI KKIPFKMVDV GGQRSQRQKW FQCFDGITSI LFMVSSSEYD 
       260        270        280        290        300
QVLMEDRRTN RLVESMNIFE TIVNNKLFIN VSIILFLNKT DLLVEKVKTV 
       310        320        330        340        350
SIKKHFPDFR GDPHRLEDVQ RYLVQCFDRK RRNRSKPLFH HFTTAIDTEN 
       360        370 
IRFVFHAVKD TILQENLKDI MLQ                              

Sequence databases

Genome annotation databases

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ

• 90% Identity
• 50% Identity

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

Keywords - Technical termⁱ