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Entry version 52 (11 Dec 2019)
Sequence version 1 (16 Nov 2011)
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Protein
Submitted name:

AT-rich interaction domain 1B

Gene

ARID1B

Organism
Loxodonta africana (African elephant)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processTranscription, Transcription regulationSAAS annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
AT-rich interaction domain 1BImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ARID1BImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiLoxodonta africana (African elephant)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9785 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaAfrotheriaProboscideaElephantidaeLoxodonta
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000007646 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusSAAS annotation

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9785.ENSLAFP00000010047

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini539 – 630ARIDInterPro annotationAdd BLAST92

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 364DisorderedSequence analysisAdd BLAST364
Regioni417 – 532DisorderedSequence analysisAdd BLAST116
Regioni633 – 863DisorderedSequence analysisAdd BLAST231
Regioni878 – 1048DisorderedSequence analysisAdd BLAST171
Regioni1186 – 1256DisorderedSequence analysisAdd BLAST71
Regioni1306 – 1344DisorderedSequence analysisAdd BLAST39

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi19 – 33PolarSequence analysisAdd BLAST15
Compositional biasi60 – 91PolarSequence analysisAdd BLAST32
Compositional biasi103 – 127PolarSequence analysisAdd BLAST25
Compositional biasi163 – 200PolarSequence analysisAdd BLAST38
Compositional biasi215 – 233PolarSequence analysisAdd BLAST19
Compositional biasi243 – 258PolarSequence analysisAdd BLAST16
Compositional biasi269 – 292PolarSequence analysisAdd BLAST24
Compositional biasi300 – 340PolarSequence analysisAdd BLAST41
Compositional biasi348 – 362PolarSequence analysisAdd BLAST15
Compositional biasi427 – 488PolarSequence analysisAdd BLAST62
Compositional biasi500 – 514PolyampholyteSequence analysisAdd BLAST15
Compositional biasi515 – 531PolarSequence analysisAdd BLAST17
Compositional biasi645 – 677PolarSequence analysisAdd BLAST33
Compositional biasi693 – 735PolarSequence analysisAdd BLAST43
Compositional biasi766 – 800PolarSequence analysisAdd BLAST35
Compositional biasi980 – 1009PolarSequence analysisAdd BLAST30
Compositional biasi1016 – 1047PolarSequence analysisAdd BLAST32
Compositional biasi1198 – 1228AcidicSequence analysisAdd BLAST31

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2510 Eukaryota
ENOG410Y034 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155634

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
G3T8M1

Identification of Orthologs from Complete Genome Data

More...
OMAi
GQMQQHG

TreeFam database of animal gene trees

More...
TreeFami
TF320364

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.150.60, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR038040 ARID1B
IPR001606 ARID_dom
IPR036431 ARID_dom_sf
IPR016024 ARM-type_fold
IPR021906 BAF250/Osa
IPR033388 BAF250_C

The PANTHER Classification System

More...
PANTHERi
PTHR12656 PTHR12656, 2 hits
PTHR12656:SF11 PTHR12656:SF11, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01388 ARID, 1 hit
PF12031 BAF250_C, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00501 BRIGHT, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46774 SSF46774, 1 hit
SSF48371 SSF48371, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51011 ARID, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

G3T8M1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
SQGSPMDPMV MKRPQLYGMG SNPHSQPQQS SPYPGGSYGP PGPQRYPISI
60 70 80 90 100
QGRTPGAMAG MQYPQQQMPP QYGQQGVSGY CQQGQQPYYN QQPQPPHLPP
110 120 130 140 150
QAQYLPSQSQ QRYQPQQDMS QEGYGTRSQP PLAPGKPNHE DLNLIQQERP
160 170 180 190 200
SSLPDLSGSI DDLPTGTEAT LSSAVSASGS TSSQGDQSNP AQSPFSPHAS
210 220 230 240 250
PHLSSIPGGP SPSPVGSPVG SNQSRSGPIS PASIPGSQMP PQPPGSQSES
260 270 280 290 300
SVHPAMSQSP MPQERGFMAG SQRNPQMSQY GPQQTGPSMS PHPSPGGQMH
310 320 330 340 350
PGISSFQQSN SSGTYGPQMS QYGPQGNYSR PPTYSGVPSA SYSGPGPGMG
360 370 380 390 400
INANSQMHGQ GPSQPCGAMP LGRMPSAGMQ SRPFPGNMSS MTPSSPGMPQ
410 420 430 440 450
QGGPGMGPPM PTVNRKAQEA AAAVMQAAAN SAQSRQGSFP SMNQSGLMAS
460 470 480 490 500
SSPYNQPMNN SSGLMNTQAP PYSMAPNMVN SSTASMGLAD MMSPGESKLP
510 520 530 540 550
LKTDGKEEGP PQPESKSKKS SSSTTTGEKI TKLYELGNEP ERKLWVDRYL
560 570 580 590 600
TFMEERGSPV SSLPAVGKKP LDLFRLYVCV KEIGGLAQVN KNKKWRELAT
610 620 630 640 650
NLNVGTSSSA ASSLKKQYIQ YLFAFECKIE RGEEPPPEVF STGDTKKQPK
660 670 680 690 700
LQPPSPANSG SLQGPQTPQS TGSNSMAEVP GDLKPPTPAS TPHGQMTPMQ
710 720 730 740 750
GGRSSTISVH DPFSDVSDSS FPKRNSMTPN APYQQGMSMP DMMGRVPYEP
760 770 780 790 800
NKDPFGGMRK VPGSSEPFMT QGQMPNSGMQ DMYNQSPSGA MSNLGMGQRQ
810 820 830 840 850
QFPYGASYDR RHEPYGQQYP GQGPPSGQPP YGGHQPGLYP QQPNYKRHMD
860 870 880 890 900
GMYGPPAKRH EGDVYNMQYG GQQQEMYSQY GSSYSGPERR PLQGQYPYPY
910 920 930 940 950
NRERLQGPGQ LQPHGLPPQM MGGPLQAASG DGPQQNMWAA RNDMPYPYQN
960 970 980 990 1000
RQGPGGPAQA PPYPGVSRTE EMMVPEQRIN HESQWPSHVS QRQPYMPSSA
1010 1020 1030 1040 1050
SMQPITRPPQ SSYQTPPSLP NHISRAPSPA SFRSLENRMS PSKSPFLPSM
1060 1070 1080 1090 1100
KMQKVMPSVP PSQVTGPPPQ PPPIRREITF PPGSVEASQP VLKQRRKITS
1110 1120 1130 1140 1150
KDIVTPEAWR VMMSLKSGLL AESTWALDTI NILLYDDSTV ATFNLSQLSG
1160 1170 1180 1190 1200
FLELLVEYFR KCLIDIFGIL MEYEVGDPSQ KALDHAAVRR DESQALADDP
1210 1220 1230 1240 1250
GREEEDAECL DDEDDEEDEE EEDSEKAETD DQSSMAFPSP DATAAPKEKP
1260 1270 1280 1290 1300
KQASRFDKLP IKLVKKNSLF VVDRSDRLGR VQEFSSGLLH WQLGGGDTTE
1310 1320 1330 1340 1350
HIQTHFESKM EIPPRRRPPP PLSSAGRKRE QEGKGDAEGQ QEKSIVATID
1360 1370 1380 1390 1400
DVLSARPGAL PEDAHPGNQA ESSKFPFGIH QAKSHRNIRL LEDEPRSRDE
1410 1420 1430 1440 1450
TPLCTVAHWQ DSLAKRCICV SNIVRSLSFV PGNDAEMSKH PGLVLILGKL
1460 1470 1480 1490 1500
ILLHHEHPER KRAPQTYEKE EDEDKGVACS KDEWWWDCLE VLRDNTLVTL
1510 1520 1530 1540 1550
ANISGQLDLS AYTESICLPI LDGLLHWMVC PSAEAQDPFP TVGPNSVLSP
1560 1570 1580 1590 1600
QRLVLETLCK LSIQDNNVDL ILATPPFSRQ EKFYATLVRY VGDRKNPVCR
1610 1620 1630 1640 1650
EMSMALLSNL AQGDALAARA IAVQKGSIGN LISFLEDGVT MAQYQQSQHS
1660 1670 1680 1690 1700
LMHLQTPPLE PPSVDMMCRA AKALLAMARV DENRSEFLLH EGRLLDISIS
1710 1720
AVLNSLVASV VCDVLFQIGQ L
Length:1,721
Mass (Da):187,175
Last modified:November 16, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2F96B8C74EA85070
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
G3U9R6G3U9R6_LOXAF
AT-rich interaction domain 1B
ARID1B
1,590Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSLAFT00000012021; ENSLAFP00000010047; ENSLAFG00000012011

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi9785.ENSLAFP00000010047

Genome annotation databases

EnsembliENSLAFT00000012021; ENSLAFP00000010047; ENSLAFG00000012011

Phylogenomic databases

eggNOGiKOG2510 Eukaryota
ENOG410Y034 LUCA
GeneTreeiENSGT00940000155634
InParanoidiG3T8M1
OMAiGQMQQHG
TreeFamiTF320364

Family and domain databases

Gene3Di1.10.150.60, 1 hit
InterProiView protein in InterPro
IPR038040 ARID1B
IPR001606 ARID_dom
IPR036431 ARID_dom_sf
IPR016024 ARM-type_fold
IPR021906 BAF250/Osa
IPR033388 BAF250_C
PANTHERiPTHR12656 PTHR12656, 2 hits
PTHR12656:SF11 PTHR12656:SF11, 2 hits
PfamiView protein in Pfam
PF01388 ARID, 1 hit
PF12031 BAF250_C, 1 hit
SMARTiView protein in SMART
SM00501 BRIGHT, 1 hit
SUPFAMiSSF46774 SSF46774, 1 hit
SSF48371 SSF48371, 1 hit
PROSITEiView protein in PROSITE
PS51011 ARID, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG3T8M1_LOXAF
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G3T8M1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: December 11, 2019
This is version 52 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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