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Entry version 41 (05 Jun 2019)
Sequence version 1 (16 Nov 2011)
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Protein
Submitted name:

Uncharacterized protein

Gene

BTBD7

Organism
Loxodonta africana (African elephant)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:BTBD7Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiLoxodonta africana (African elephant)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9785 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaAfrotheriaProboscideaElephantidaeLoxodonta
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000007646 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9785.ENSLAFP00000004447

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini142 – 211BTBInterPro annotationAdd BLAST70
Domaini247 – 341BTBInterPro annotationAdd BLAST95

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni892 – 1012DisorderedSequence analysisAdd BLAST121
Regioni1028 – 1048DisorderedSequence analysisAdd BLAST21
Regioni1060 – 1125DisorderedSequence analysisAdd BLAST66

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi920 – 934PolyampholyteSequence analysisAdd BLAST15
Compositional biasi993 – 1012PolyampholyteSequence analysisAdd BLAST20
Compositional biasi1060 – 1074PolarSequence analysisAdd BLAST15
Compositional biasi1095 – 1117PolyampholyteSequence analysisAdd BLAST23

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2838 Eukaryota
ENOG410XP1W LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000014092

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
G3SVZ9

KEGG Orthology (KO)

More...
KOi
K10479

Identification of Orthologs from Complete Genome Data

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OMAi
NMLAQGC

Database of Orthologous Groups

More...
OrthoDBi
73978at2759

TreeFam database of animal gene trees

More...
TreeFami
TF316112

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011705 BACK
IPR000210 BTB/POZ_dom
IPR011333 SKP1/BTB/POZ_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07707 BACK, 1 hit
PF00651 BTB, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00875 BACK, 1 hit
SM00225 BTB, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54695 SSF54695, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50097 BTB, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

G3SVZ9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGANASNYPH SCSPRVGANS QAQQTFIGTS SYSQQGYGCE SKLYSLDHGH
60 70 80 90 100
EKPQDKKKRT SGLATLKKKF IKRRKSNRSA DHAKQMREFL SGWDVRDVNA
110 120 130 140 150
LVEEYEGTSA LKELSLQASL ARPEAQTLQK DMADLYEYKY CTDVDLIFQE
160 170 180 190 200
TCFPVHRAIL AARCPFFKTL LSSSPEYGAE IVMDINTAGI DMPMFSALLH
210 220 230 240 250
YLYTGEFGME DSRFQNVDIL VQLSEEFGTP NSLDVDMRGL FDYMCYYDVV
260 270 280 290 300
LSFSSDSELV EAFGGNQNCL DEELKAHKAI ISARSPFFRN LLQRRIRTGE
310 320 330 340 350
EITDRTLRTP TRIILDESII PKKYAKVILH CMYTDVVDLS VLHCSLSVGS
360 370 380 390 400
LSEVQALVAG KPNMTRAEEA MELYHIALFL EFNMLAQGCE DIIAESISLD
410 420 430 440 450
TLIAILKWSS HPYGSKWVHR QALHFLCEEF SQVMTSDVFY ELSKDHLLTA
460 470 480 490 500
IQSDYLQASE QDVLKYLIKW GEHQLMKRIA DREPNLLSGT AHSVNKRGVK
510 520 530 540 550
RRDLDVEELR EILSSLLPFV RIEHILPINS EILSDAMKRG LISTPPSDML
560 570 580 590 600
PTTEGGKSNA WLRQKNAGIY VRPRLFSPYV EEAKSVLDEM MVEQTDLVRL
610 620 630 640 650
RMVRMSNVPD TLYMVSNAVP QCCHMASHQQ ISSNQSSPPS VVANEIPVPR
660 670 680 690 700
LLTMKDMVRR LQELRHTEQV QRAYALNCGE GATVSYEIQI RVLREFGLAD
710 720 730 740 750
AAAELLQNPH KFFPDERFGD ESPLLTMKQA GRCRVNSTPT AETMFTDLDS
760 770 780 790 800
FVAFHPPLPP PPPPYHPPAT PIHNQLKVGW KQKPPSQHPS RSFSYPCSHS
810 820 830 840 850
LFHSRTPPKA VPPPVYLPSI KAAPPDCTNT AGLGRQTVAA AAAASAAMTS
860 870 880 890 900
EKQVCTQPVL NELMPDIAMG VSTLSLKDRR LPELAVDTEL SQSVSKVGPG
910 920 930 940 950
PPQHLSCIPQ RHSHTSQKKH TLERKTDPRE NPQEYPDFYD FSNAACRPST
960 970 980 990 1000
PAPSRRSPPP SQAGYFGPDL YSHNKASPGG LKSAYLPSQT SPKKQEEARR
1010 1020 1030 1040 1050
EYPLSPDGHL HRQKSEPIHL DVIEQPPQRS DFPLAAPENA GNGPAHMRGR
1060 1070 1080 1090 1100
TAVETDLTFG LTSNRPSHSA CSSEAPEERS TRRLADSESL GHGAQRNPDL
1110 1120
EREDSVSRGR RSPSKPDFLY KKSAL
Length:1,125
Mass (Da):125,831
Last modified:November 16, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF464084A6A1E1CD1
GO

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
XP_003408891.1, XM_003408843.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSLAFT00000005313; ENSLAFP00000004447; ENSLAFG00000005312

Database of genes from NCBI RefSeq genomes

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GeneIDi
100669939

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
lav:100669939

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_003408891.1, XM_003408843.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi9785.ENSLAFP00000004447

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSLAFT00000005313; ENSLAFP00000004447; ENSLAFG00000005312
GeneIDi100669939
KEGGilav:100669939

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
55727

Phylogenomic databases

eggNOGiKOG2838 Eukaryota
ENOG410XP1W LUCA
GeneTreeiENSGT00390000014092
InParanoidiG3SVZ9
KOiK10479
OMAiNMLAQGC
OrthoDBi73978at2759
TreeFamiTF316112

Family and domain databases

InterProiView protein in InterPro
IPR011705 BACK
IPR000210 BTB/POZ_dom
IPR011333 SKP1/BTB/POZ_sf
PfamiView protein in Pfam
PF07707 BACK, 1 hit
PF00651 BTB, 2 hits
SMARTiView protein in SMART
SM00875 BACK, 1 hit
SM00225 BTB, 2 hits
SUPFAMiSSF54695 SSF54695, 2 hits
PROSITEiView protein in PROSITE
PS50097 BTB, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG3SVZ9_LOXAF
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G3SVZ9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: June 5, 2019
This is version 41 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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