UniProtKB - G3SPS1 (G3SPS1_LOXAF)
Protein
Submitted name:
Forkhead box F2
Gene
FOXF2
Organism
Loxodonta africana (African elephant)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 92 – 186 | Fork-headPROSITE-ProRule annotationAdd BLAST | 95 |
GO - Molecular functioni
- DNA-binding transcription activator activity, RNA polymerase II-specific Source: Ensembl
- RNA polymerase II transcription regulatory region sequence-specific DNA binding Source: Ensembl
- transcription factor binding Source: Ensembl
GO - Biological processi
- embryonic camera-type eye morphogenesis Source: Ensembl
- embryonic digestive tract development Source: Ensembl
- establishment of planar polarity of embryonic epithelium Source: Ensembl
- extracellular matrix organization Source: Ensembl
- genitalia development Source: Ensembl
- negative regulation of transcription, DNA-templated Source: Ensembl
- regulation of proteasomal ubiquitin-dependent protein catabolic process Source: Ensembl
- regulation of protein polyubiquitination Source: Ensembl
- roof of mouth development Source: Ensembl
Keywordsi
Molecular function | DNA-bindingPROSITE-ProRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Forkhead box F2Imported |
Gene namesi | Name:FOXF2Imported |
Organismi | Loxodonta africana (African elephant)Imported |
Taxonomic identifieri | 9785 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Afrotheria › Proboscidea › Elephantidae › Loxodonta |
Proteomesi |
|
Subcellular locationi
Nucleus
- Nucleus PROSITE-ProRule annotationARBA annotation
Nucleus
- nucleus Source: UniProtKB-SubCell
Other locations
- transcription regulator complex Source: Ensembl
Keywords - Cellular componenti
NucleusPROSITE-ProRule annotationInteractioni
GO - Molecular functioni
- transcription factor binding Source: Ensembl
Protein-protein interaction databases
STRINGi | 9785.ENSLAFP00000001733 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 92 – 186 | Fork-headInterPro annotationAdd BLAST | 95 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 90 | DisorderedSequence analysisAdd BLAST | 90 | |
Regioni | 249 – 270 | DisorderedSequence analysisAdd BLAST | 22 | |
Regioni | 299 – 323 | DisorderedSequence analysisAdd BLAST | 25 | |
Regioni | 336 – 366 | DisorderedSequence analysisAdd BLAST | 31 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 33 – 47 | PolarSequence analysisAdd BLAST | 15 |
Phylogenomic databases
eggNOGi | KOG2294, Eukaryota |
GeneTreei | ENSGT00940000162527 |
HOGENOMi | CLU_039845_1_0_1 |
InParanoidi | G3SPS1 |
OMAi | TLACHSN |
TreeFami | TF351598 |
Family and domain databases
CDDi | cd00059, FH, 1 hit |
Gene3Di | 1.10.10.10, 1 hit |
InterProi | View protein in InterPro IPR001766, Fork_head_dom IPR018122, TF_fork_head_CS_1 IPR030456, TF_fork_head_CS_2 IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
Pfami | View protein in Pfam PF00250, Forkhead, 1 hit |
PRINTSi | PR00053, FORKHEAD |
SMARTi | View protein in SMART SM00339, FH, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit |
PROSITEi | View protein in PROSITE PS00657, FORK_HEAD_1, 1 hit PS00658, FORK_HEAD_2, 1 hit PS50039, FORK_HEAD_3, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
G3SPS1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
RPPPAPLRRA CSPGPGALQA ALMSPPPAAA AALESASSSS SSAASAASAP
60 70 80 90 100
CAPAAPTPSS ASAVTSKGLG GGGSTGGGAP KKASSGLRRP EKPPYSYIAL
110 120 130 140 150
IVMAIQSSPS KRLTLSEIYQ FLQARFPFFR GAYQGWKNSV RHNLSLNECF
160 170 180 190 200
IKLPKGLGRP GKGHYWTIDP ASEFMFEEGS FRRRPRGFRR KCQALKPMYH
210 220 230 240 250
RVVGGLGFGA SLLPQGFDFQ APPAAPLGCH SQGGYGGLDM MPAGYDAGAG
260 270 280 290 300
APGHAHPHHH HHHHVPHMSP NPGSTYMASC PVPAGPGGVG AAGCSSGGGG
310 320 330 340 350
GGGGGGDYGP DSSSSPVPSS PAMASAIECH SPYTSPAAHW SSPGASPYLK
360 370 380 390 400
QPPALTPSGN PAASAGLHSS MSSYSLEQNY LHQNAREDLS VGLTRYQHHS
410 420 430 440
TPVCDRKDFV LNFNGISSFH PSASGSYYHH HHHQSVCQDI KPCVM
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketG3U775 | G3U775_LOXAF | Forkhead box F2 | FOXF2 | 428 | Annotation score: |
Genome annotation databases
Ensembli | ENSLAFT00000002074; ENSLAFP00000001733; ENSLAFG00000002074 |
Similar proteinsi
Cross-referencesi
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 9785.ENSLAFP00000001733 |
Genome annotation databases
Ensembli | ENSLAFT00000002074; ENSLAFP00000001733; ENSLAFG00000002074 |
Phylogenomic databases
eggNOGi | KOG2294, Eukaryota |
GeneTreei | ENSGT00940000162527 |
HOGENOMi | CLU_039845_1_0_1 |
InParanoidi | G3SPS1 |
OMAi | TLACHSN |
TreeFami | TF351598 |
Family and domain databases
CDDi | cd00059, FH, 1 hit |
Gene3Di | 1.10.10.10, 1 hit |
InterProi | View protein in InterPro IPR001766, Fork_head_dom IPR018122, TF_fork_head_CS_1 IPR030456, TF_fork_head_CS_2 IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
Pfami | View protein in Pfam PF00250, Forkhead, 1 hit |
PRINTSi | PR00053, FORKHEAD |
SMARTi | View protein in SMART SM00339, FH, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit |
PROSITEi | View protein in PROSITE PS00657, FORK_HEAD_1, 1 hit PS00658, FORK_HEAD_2, 1 hit PS50039, FORK_HEAD_3, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | G3SPS1_LOXAF | |
Accessioni | G3SPS1Primary (citable) accession number: G3SPS1 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 16, 2011 |
Last sequence update: | November 16, 2011 | |
Last modified: | August 12, 2020 | |
This is version 60 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |