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Protein

Angiotensin-converting enzyme

Gene
N/A
Organism
Gorilla gorilla gorilla (Western lowland gorilla)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cofactori

Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionCarboxypeptidaseUniRule annotation, Hydrolase, MetalloproteaseUniRule annotation, Protease
LigandMetal-bindingUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Angiotensin-converting enzymeUniRule annotation (EC:3.4.-.-UniRule annotation)
OrganismiGorilla gorilla gorilla (Western lowland gorilla)Imported
Taxonomic identifieri9595 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeGorilla
Proteomesi
  • UP000001519 Componenti: Chromosome 5

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei686 – 707HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_501411457122 – 732Angiotensin-converting enzymeSequence analysisAdd BLAST711

Keywords - PTMi

GlycoproteinUniRule annotation

Expressioni

Gene expression databases

BgeeiENSGGOG00000000642

Interactioni

Protein-protein interaction databases

STRINGi9593.ENSGGOP00000021381

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase M2 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

GeneTreeiENSGT00520000055576
InParanoidiG3RZY8
KOiK01283
OMAiVTMEQLF
OrthoDBiEOG091G033S
TreeFamiTF312861

Family and domain databases

CDDicd06461 M2_ACE, 1 hit
InterProiView protein in InterPro
IPR001548 Peptidase_M2
PANTHERiPTHR10514 PTHR10514, 1 hit
PfamiView protein in Pfam
PF01401 Peptidase_M2, 1 hit
PRINTSiPR00791 PEPDIPTASEA

Sequencei

Sequence statusi: Complete.

G3RZY8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGQGWATAGL PSLLFLLLCY GHPLLVPSQE APQQVTVTHG TSSQATTSGQ
60 70 80 90 100
TTTHQATAHQ TSAQSPNLVT DEAEASKFVE EYDRTSQVVW NEYAEANWNY
110 120 130 140 150
NTNITTETSK ILLQKNMQIA NHTLKYGTQA RRFDVNQLQN TTIKRIIKKV
160 170 180 190 200
QDLERAALPA QELEEYNKIL LDMETTYSVA TVCHTNGSCL QLEPDLTNVM
210 220 230 240 250
ATSRKYEDLL WAWEGWRDKA GRAILQFYPK YVELINQAAR LNGYVDAGDS
260 270 280 290 300
WRSMYETPSL EQDLERLFQE LQPLYLNLHA YVRRALHRHY GAQHINLEGP
310 320 330 340 350
IPAHLLGNMW AQTWSNIYDL VVPFPSAPSM DATEAMLKQG WTPRRMFKEA
360 370 380 390 400
DDFFTSLGLL PVPPEFWNKS MLEKPTDGRE VVCHASAWDF YNGKDFRIKQ
410 420 430 440 450
CTTVNLEDLV VAHHEMGHIQ YFMQYKDLPV ALREGANPGF HEAIGDVLAL
460 470 480 490 500
SVSTPKHLHS LNLLSSEGGS DEHDINFLMK MALDKIAFIP FSYLVDQWRW
510 520 530 540 550
RVFDGSITKE NYNQEWWSLR LKYQGLCPPV PRTQGDFDPG AKFHVPSSVP
560 570 580 590 600
YIRYFVSFII QFQFHEALCQ AAGHTGPLHK CDIYQSKEAG QRLATAMKLG
610 620 630 640 650
FSRPWPEAMQ LITGQPNMSA SAMLSYFKPL LDWLRTENEL HGEKLGWPQY
660 670 680 690 700
NWTPNSARSE GPLPDSGRVS FLGLDLDAQQ ARVGQWLLLF LGIALLVATL
710 720 730
GLSQRLFSIR HRSLHRHSHG PQFGSEVELR HS
Length:732
Mass (Da):83,298
Last modified:February 28, 2018 - v2
Checksum:i1FB416EA051F2B2C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CABD030036630 Genomic DNA No translation available.
CABD030036631 Genomic DNA No translation available.
RefSeqiXP_004041197.1, XM_004041149.2

Genome annotation databases

EnsembliENSGGOT00000029973; ENSGGOP00000021381; ENSGGOG00000000642
GeneIDi101145787
KEGGiggo:101145787

Similar proteinsi

Entry informationi

Entry nameiG3RZY8_GORGO
AccessioniPrimary (citable) accession number: G3RZY8
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: February 28, 2018
Last modified: June 20, 2018
This is version 45 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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