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Protein
Submitted name:

5-hydroxytryptamine receptor 4

Gene

HTR4

Organism
Gorilla gorilla gorilla (Western lowland gorilla)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
5-hydroxytryptamine receptor 4Imported
Gene namesi
Name:HTR4Imported
OrganismiGorilla gorilla gorilla (Western lowland gorilla)Imported
Taxonomic identifieri9595 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeGorilla
Proteomesi
  • UP000001519 Componenti: Chromosome 5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei20 – 45HelicalSequence analysisAdd BLAST26
Transmembranei57 – 79HelicalSequence analysisAdd BLAST23
Transmembranei99 – 117HelicalSequence analysisAdd BLAST19
Transmembranei138 – 158HelicalSequence analysisAdd BLAST21
Transmembranei192 – 213HelicalSequence analysisAdd BLAST22
Transmembranei260 – 281HelicalSequence analysisAdd BLAST22
Transmembranei293 – 315HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSGGOG00000016400

Interactioni

Protein-protein interaction databases

STRINGi9593.ENSGGOP00000017366

Structurei

3D structure databases

ProteinModelPortaliG3RNJ9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini36 – 312G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST277

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

GeneTreeiENSGT00890000139340
InParanoidiG3RNJ9
OMAiYRIYITA
OrthoDBiEOG091G06VI
TreeFamiTF316350

Family and domain databases

CDDicd15056 7tmA_5-HT4, 1 hit
InterProiView protein in InterPro
IPR001520 5HT4_rcpt
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR01059 5HT4RECEPTR
PR00237 GPCRRHODOPSN
SMARTiView protein in SMART
SM01381 7TM_GPCR_Srsx, 1 hit
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Complete.

G3RNJ9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDKLDANVSS EEGFGSVEKV VLLTFLSTVI LMAILGNLLV MVAVCWDRQL
60 70 80 90 100
RKIKTNYFIV SLAFADLLVS VLVMPFGAIE LVQDIWIYGE MFCLVRTSLD
110 120 130 140 150
VLLTTASIFH LCCISLDRYY AICCQPLVYR NKMTPLRIAL MLGGCWVIPT
160 170 180 190 200
FISFLPIMQG WNNIGIIDLI EKRKFNQNSN STYCVFMVNK PYAITCSVVA
210 220 230 240 250
FYIPFLLMVL AYYRIYVTAK EHAHQIQMLQ RAGASSESRP QSADQHSTHR
260 270 280 290 300
MRTETKAAKT LCIIMGCFCL CWAPFFVTNI VDPFIDYTVP GQVWTAFLWL
310 320 330 340 350
GYINSGLNPF LYAFLNKSFR RAFLIILCCD DERYRRPSIL GQTVPCSTTT
360 370 380 390 400
INGSTHVLRT DFLFDRDILA RYWTKPARAG PFSGTLSIRC LTARKPVLGD
410 420
AVECGGQWES QCHPPATSPL VAAQPSDT
Length:428
Mass (Da):48,287
Last modified:November 16, 2011 - v1
Checksum:iC4C80A51848D3798
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CABD030041637 Genomic DNA No translation available.
CABD030041638 Genomic DNA No translation available.
CABD030041639 Genomic DNA No translation available.
CABD030041640 Genomic DNA No translation available.
CABD030041641 Genomic DNA No translation available.
RefSeqiXP_004042828.1, XM_004042780.2

Genome annotation databases

EnsembliENSGGOT00000029319; ENSGGOP00000017366; ENSGGOG00000016400
GeneIDi101142127

Similar proteinsi

Entry informationi

Entry nameiG3RNJ9_GORGO
AccessioniPrimary (citable) accession number: G3RNJ9
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: May 23, 2018
This is version 43 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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