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Entry version 56 (11 Dec 2019)
Sequence version 2 (28 Feb 2018)
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Protein
Submitted name:

Ecm29 proteasome adaptor and scaffold

Gene
N/A
Organism
Gorilla gorilla gorilla (Western lowland gorilla)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Ecm29 proteasome adaptor and scaffoldImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiGorilla gorilla gorilla (Western lowland gorilla)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9595 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeGorilla
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001519 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 9

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSGGOG00000012416 Expressed in 6 organ(s), highest expression level in prefrontal cortex

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9593.ENSGGOP00000012145

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1321 – 1402Vac14_Fab1_bdInterPro annotationAdd BLAST82

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni29 – 181DisorderedSequence analysisAdd BLAST153
Regioni365 – 389DisorderedSequence analysisAdd BLAST25

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi57 – 72PolyampholyteSequence analysisAdd BLAST16
Compositional biasi365 – 385PolarSequence analysisAdd BLAST21

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153612

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
G3R9Q4

TreeFam database of animal gene trees

More...
TreeFami
TF314213

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.10.10, 3 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR024372 Ecm29
IPR032878 Vac14_Fab1-bd

The PANTHER Classification System

More...
PANTHERi
PTHR23346:SF19 PTHR23346:SF19, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13001 Ecm29, 1 hit
PF12755 Vac14_Fab1_bd, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371 SSF48371, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

G3R9Q4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTSRTKRRRK VKISISKINH SGYRKEHRPF WEHQPPPHQN AAVGGRCGAG
60 70 80 90 100
ARPGLSQRRG REVRREAQGG ASSRRLRARL YFSESTSLPL DRRGSPGPLG
110 120 130 140 150
PAPHGLRRAA PRGPARRTPR STALTSRRRA QRPRHGDRLR LRSEARPRAA
160 170 180 190 200
GDWPCARGGA VRPGRPHRPP RVESARGAHA GRAATDQLER VFLRLGHAET
210 220 230 240 250
DEQLQNIISK FLPPVLLKLS STQEGVRKKV MELLVHLNKR IKSRPKIQLP
260 270 280 290 300
VETLLVQYQD PAAVSFVTNF TIIYVKMGYP RLPVEKQCEL APTLLTAMEG
310 320 330 340 350
KPQPQQDSLM HLLIPTLFHM KYPVESSKSA SPFNLAEKPK TVQLLLDFML
360 370 380 390 400
DVLLMPYGYV LNESQSRQNS SSAQGSSSNS GGGSGIPQPP PGMSFYAAKR
410 420 430 440 450
VIGDNPWTPE QLEQCKLGIV KFIEAEQVPE LEAVLHLVIA SSDTRHSVAT
460 470 480 490 500
AADLELKSKQ SLIDWNNPAI INKMYKVYLG DIPLKTKEGA VLKPELKRDP
510 520 530 540 550
VSTRVKLKIV PHLLRSRQAA ETFPANIQVV YDGLFGTNTN SKLRTLSLQF
560 570 580 590 600
VHHICITCPE IKIKPLGPML LNGLTKLINE YKEDPKLLSM AYSAVGKLSS
610 620 630 640 650
RMPHLFTKDI ALVQQLFEAL CKEEPETRLA IQEALSMMVG AYSTLEGAQR
660 670 680 690 700
TLMEALVASY LIKPEVQVRQ VAVKFASTVF PSDHIPSRYL LLLAAGDPRE
710 720 730 740 750
EVHGEAQRVL RCLPGRNRKE STSEQMPSFP EMVYYIQEKA SHRMKTPVKY
760 770 780 790 800
MTGTTVLPFN PAAFGEIVLY LRMCLAHSAG VVPTSQSLAD MQDHAPAIGR
810 820 830 840 850
YIRTLMSSGQ TAPSSSNKSG ETNPVQIYVG LLQQLLAGVG GLPVMYCLLE
860 870 880 890 900
AVSVYPEKLA TKFVDKAEWI KSLMNSSKEE MRELAALFYS VVVSTVSGNE
910 920 930 940 950
LKSMIEQLIK TTKDNHSPEI QHGSLLALGF TVGRYLAKKK MRMSEQQDLE
960 970 980 990 1000
RNADTLPDQE ELIQSATETI GSFLDSTSPL LAIAACTALG EIGRNGPLPI
1010 1020 1030 1040 1050
PSEGSGFTKL HLVESLLSRI PSSKETNKMK ERAIQTLGYF PVGDGDFPHQ
1060 1070 1080 1090 1100
KLLLQGLMDS VEAKQIELQF TIGEAITSAA IGTSSVAARD AWQVTEEEYT
1110 1120 1130 1140 1150
PPAGAKVNDV VPWVLDVILN KHIISPNPHV RQAACIWLLS LVRKLSTHKE
1160 1170 1180 1190 1200
VKSHLKEIQS AFVSVLSEND ELSQDVASKG LGLVYELGNE QDQQELVSTL
1210 1220 1230 1240 1250
VETLMTGKRV KHEVSGETVV FQGGALGKTP DGQGLSTYKE LCSLASDLSQ
1260 1270 1280 1290 1300
PDLVYKFMNL ANHHAMWNSR KGAAFGFNVI ATRAGEQLAP FLPQLVPRLY
1310 1320 1330 1340 1350
RYQFDPNLGI RQAMTSIWNA LVTDKSMVDK YLKEILQDLV KNLTSNMWRV
1360 1370 1380 1390 1400
RESSCLALND LLRGRPLDDI IDKLPEIWET LFRVQDDIKE SVRKAAELAL
1410 1420 1430 1440 1450
KTLSKVCVKM CDPAKGAAGQ RTIAALLPCL LDKGMMSPVT EVRALSINTL
1460 1470 1480 1490 1500
VKISKSAGAM LKPHAPKLIP ALLESLSVLE PQVLNYLSLR ATEQEKAAMD
1510 1520 1530 1540 1550
SARLSAAKSS PMMETINMCL QYLDVSVLGE LVPRLCELIR SGVGLGTKGG
1560 1570 1580 1590 1600
CASVIVSLTT QCPQDLTPYS GKLMSALLSG LTDRNSVIQK SSAFAMGHLV
1610 1620 1630 1640 1650
RTSRDSSTEK LLQKLNGWYM EKEEPIYKTS CALTIHAIGR YSPDVLKNHA
1660 1670 1680 1690 1700
KEVLPLAFLG MHEIADEEKS EKEECNLWTE VWQENVPGSF GGIRLYLQEL
1710 1720 1730 1740 1750
ITITQKALQS QSWKMKAQGA IAMASIAKQT SSLVPPYLGM ILTALLQGLA
1760 1770 1780 1790 1800
GRTWAGKEEL LKAIACVVTA CSAELEKSVP NQPSTNEILQ AVLKECSKEN
1810 1820 1830 1840 1850
LKYKIVAISC AADILKATKE DRFQEFSDIV IPLIKKNSLE SSGVRTTKNE
1860 1870 1880 1890 1900
EENEKEKELQ LEYLLGAFES LGKAWPRNAE TQRCYRQELC KLMCERLKLS
1910 1920 1930 1940 1950
TWKVQLGVLQ SMNAFFQGLM LLEEEHADPE ALAEILLETC KSITYSLENK
1960 1970 1980 1990 2000
TYSSVRTEAL SVIELLLKKL EESKQWECLT SECRVLLIES LATMEPDSRP
2010
ELQEKAALLK KTLENLE
Length:2,017
Mass (Da):223,439
Last modified:February 28, 2018 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8A22DE033E59F313
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
G3RVE1G3RVE1_GORGO
Ecm29 proteasome adaptor and scaffo...
1,838Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2I2Y4P9A0A2I2Y4P9_GORGO
Ecm29 proteasome adaptor and scaffo...
1,832Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2I2ZN54A0A2I2ZN54_GORGO
Ecm29 proteasome adaptor and scaffo...
1,788Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CABD030065862 Genomic DNA No translation available.
CABD030065863 Genomic DNA No translation available.
CABD030065864 Genomic DNA No translation available.
CABD030065865 Genomic DNA No translation available.
CABD030065866 Genomic DNA No translation available.
CABD030065867 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSGGOT00000012495; ENSGGOP00000012145; ENSGGOG00000012416

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CABD030065862 Genomic DNA No translation available.
CABD030065863 Genomic DNA No translation available.
CABD030065864 Genomic DNA No translation available.
CABD030065865 Genomic DNA No translation available.
CABD030065866 Genomic DNA No translation available.
CABD030065867 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi9593.ENSGGOP00000012145

Genome annotation databases

EnsembliENSGGOT00000012495; ENSGGOP00000012145; ENSGGOG00000012416

Phylogenomic databases

GeneTreeiENSGT00940000153612
InParanoidiG3R9Q4
TreeFamiTF314213

Gene expression databases

BgeeiENSGGOG00000012416 Expressed in 6 organ(s), highest expression level in prefrontal cortex

Family and domain databases

Gene3Di1.25.10.10, 3 hits
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR024372 Ecm29
IPR032878 Vac14_Fab1-bd
PANTHERiPTHR23346:SF19 PTHR23346:SF19, 1 hit
PfamiView protein in Pfam
PF13001 Ecm29, 1 hit
PF12755 Vac14_Fab1_bd, 1 hit
SUPFAMiSSF48371 SSF48371, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG3R9Q4_GORGO
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G3R9Q4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: February 28, 2018
Last modified: December 11, 2019
This is version 56 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
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