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Entry version 55 (26 Feb 2020)
Sequence version 2 (28 Feb 2018)
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Protein
Submitted name:

PKHD1 ciliary IPT domain containing fibrocystin/polyductin

Gene
N/A
Organism
Gorilla gorilla gorilla (Western lowland gorilla)
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
PKHD1 ciliary IPT domain containing fibrocystin/polyductinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiGorilla gorilla gorilla (Western lowland gorilla)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9595 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeGorilla
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001519 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei3735 – 3758HelicalSequence analysisAdd BLAST24

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 17Sequence analysisAdd BLAST17
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_501414515118 – 3950Sequence analysisAdd BLAST3933

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSGGOG00000010943 Expressed in adult mammalian kidney and 2 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9593.ENSGGOP00000010698

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini309 – 472PA14InterPro annotationAdd BLAST164
Domaini1858 – 1979G8InterPro annotationAdd BLAST122
Domaini2623 – 2749G8InterPro annotationAdd BLAST127

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni3764 – 3802DisorderedSequence analysisAdd BLAST39

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi3784 – 3802PolyampholyteSequence analysisAdd BLAST19

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160697

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000057_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
G3R5W5

TreeFam database of animal gene trees

More...
TreeFami
TF329582

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.160.20.10, 2 hits
2.60.40.10, 5 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR039448 Beta_helix
IPR019316 G8_domain
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
IPR002909 IPT_dom
IPR037524 PA14/GLEYA
IPR006626 PbH1
IPR012334 Pectin_lyas_fold
IPR011050 Pectin_lyase_fold/virulence
IPR028839 PKHD1

The PANTHER Classification System

More...
PANTHERi
PTHR46769:SF1 PTHR46769:SF1, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13229 Beta_helix, 1 hit
PF10162 G8, 2 hits
PF01833 TIG, 7 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01225 G8, 2 hits
SM00429 IPT, 6 hits
SM00710 PbH1, 10 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF51126 SSF51126, 2 hits
SSF81296 SSF81296, 6 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51484 G8, 2 hits
PS51820 PA14, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

G3R5W5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTAWLISLMS IEVLLLAVPH LSLHTEPEEG SLAGGTWITV IFDGLELGVL
60 70 80 90 100
YPNNGSQLEI HLVNMNMVVP ALRSIPCDVF PVFLDLPVVT CRTRSVLSEA
110 120 130 140 150
HEGLYFLEAY FGGQLVSSPN PGPRDSCTFK FSKAQTPIVH QVYPPSGVPG
160 170 180 190 200
KKSSIKIGII VNLFAKACCK PSPVILEAQG DKWVTPCSLI NRQMGSRYPI
210 220 230 240 250
QEDHGLGTLQ CRVEGDYIGL LEKSMVHKKA WLISAKQDLF LYQTHSEILS
260 270 280 290 300
VFPETGSLGG RTDITITGDF FDNSAQVTIA GIPCDIRHVS PRKIECTTRA
310 320 330 340 350
PGKDVRLTTP QPGNRGLLFE VGDAVEGLEL TEATPGYRWQ IVPNASSPFG
360 370 380 390 400
FWSQEGQPFR ARLSGFFVAP ETNNYTFWIQ ADSQASLHFS WSEEPRTKVK
410 420 430 440 450
VASISVGTAD WFDSWEQNRD EGTWQQKTPK LELLGGAMYY LEAEHHGIAP
460 470 480 490 500
SRGMRIGVQI HNTWLNPDVV TTYLREKHQI RVRAQRLPEV QLLTQGCMGN
510 520 530 540 550
WVRTGVFLSP EVSNSDGDLT SGTEPFCGRF SLRQPRHLVL TPPAAQKGYR
560 570 580 590 600
LDQYTHLCLA YKGHMNKILK MTVSFTIGFQ NMVKNTTCDW SLTRTSPESW
610 620 630 640 650
QFHCTDIWET CVRCSGDLQP PPANSPVLVH QIDLLPLAQE TGLFYVDEII
660 670 680 690 700
IADTNVTVSQ ADSGTARPGG NLVESVSVVG SPPVYSVTSW LAGCGTELPL
710 720 730 740 750
ITARSVLTEG SPENLIVSVF SVSKPSLTDV PVQISAHHLH QLLQNNADDF
760 770 780 790 800
TSRYLNASDF TVKEDLYTCY EHVWTLSWST QIGDLPNFIR VSDENLTGVN
810 820 830 840 850
PAAATRVVYD GGVFLGPIFG DMLATANQHT QVVVRVNDVP AHCPGSCSFQ
860 870 880 890 900
YLQGSTPCVH SVWYSVDGDI NLMIYITGTG FSGDSQFLQV TVNKTSCKVI
910 920 930 940 950
FSNQTNVVCQ TDLLPVGMHR ILMMVRPSGL AISATGEDLF LNVEPRLDMV
960 970 980 990 1000
EPSRAADIGG LWATIRGSSL EGVSLILFGS YSCAINVTTS NSSRIQCKVP
1010 1020 1030 1040 1050
PRGKDGRIVN VTVIRGDYSA VLPRAFTYVS SLNPVIVTLS RNTSNIAGGE
1060 1070 1080 1090 1100
TLVIGVARLV NCTDLDVEVH VQDALAPVHT QSAWGLEVAL PPLPAGLHRI
1110 1120 1130 1140 1150
SVSINGVSIR SQGVDLHIQY LTEVFSIEPC CGSLLGGTIL SISGIGFSRD
1160 1170 1180 1190 1200
PALVWVLVGN RSCDIVNLTE VSIWCETLPA PQIPHAGAPT VPAVVEVWAG
1210 1220 1230 1240 1250
NRSFARGPSP SLVGKGFTFM YEAAATPVVT AMQGEITNSS LSLHVGGSNL
1260 1270 1280 1290 1300
SNSVILLGNL NCDVETQSFQ GNVSLSGCSI PLHSLEAGIY PLQVRQKQMG
1310 1320 1330 1340 1350
FANMSVVLQQ FAVMPRIMAI FPSQGSACGG TILTVRGLLL NSRRRSVRVD
1360 1370 1380 1390 1400
LSGPFTCVIL SLGDHTILCQ VILEGDPLPG ASFSLNVTVL VNGLTSECQG
1410 1420 1430 1440 1450
NCTLFIREEA SPVMDALSTN TSGSLTTVLI RGQRLATTAD ELMVFVDDQL
1460 1470 1480 1490 1500
SCNVTFFNAS HVVCQTRDLA PGPHYLSVFY TRNGYACSGN VSRNFYIMPQ
1510 1520 1530 1540 1550
VFHYFPKNFS IHGGSLLTIE GTGLRGQNTT SVYVDQQACL TVNIGAELIR
1560 1570 1580 1590 1600
CIVPTGNGSV ALEIEVDGLW YHIGVIGYNN AFTPELISIS QNDDILTFAV
1610 1620 1630 1640 1650
AQISGAANID IFIGMSPCVG VSGNHTVLQC VVPSLPAGEY HVRGYDCIRG
1660 1670 1680 1690 1700
WASSALVFTS RVIITAVTEN FGCLGGRLVH VFGAGFSPGN VSAAVCGAPC
1710 1720 1730 1740 1750
RVLANATVSA FSCLVLPLDV SLAFLCGLKR EEDSCEAARH TYVQCDLTVA
1760 1770 1780 1790 1800
MATEQLLESW PYLYICEESS QCLFVPDHWA ESMFPSFSGL FISPKVERDE
1810 1820 1830 1840 1850
VLIYNSSCNI TMETEAEMEC ETPNQPITVK ITEIRKRWGQ NTQGNFSLQF
1860 1870 1880 1890 1900
CRRWSRTHSW FPERLPQDGD NVTVENGQLL LLDTNTSILN LLHIRGGKLI
1910 1920 1930 1940 1950
FMAPGPIELR AHAILVSDGG ELRIGSEDKP FQGRAQITLY GSSYSTPFFP
1960 1970 1980 1990 2000
YGVKFLAVRN GTLSLHGSLP EVIVTRLRAT AHALDTVLAL EDAVDWHPGD
2010 2020 2030 2040 2050
EVVIISGTGV KGAKPMEEIV TVETVQDTDL YLKSPLRYSH NFTENWVAGE
2060 2070 2080 2090 2100
HHILKATVAL LSRSITIQGN LTNEREKLLV SCQEANAPEG NLQHCLYSMS
2110 2120 2130 2140 2150
EKMLGSRDMG ARVIVQSFPE EPSQVQLKGV QFQVLGQAFH KHLSSLTLVG
2160 2170 2180 2190 2200
AMRESFIQGC TVRNSFSRGL SMCGTLGLKV DSNVFYNILG HALLVGTCME
2210 2220 2230 2240 2250
MRYISWEAIR GRKDDWSGHG NIIRNNVIIR VSGAEGLSNP EMLTPSGIYI
2260 2270 2280 2290 2300
CSPTNVIEGN RVCGAGYGYF FHLMTNQTSQ APLLSFTQNI AHSCTRYGLF
2310 2320 2330 2340 2350
VYPKFQPPWD NVTGTTLFQS FTVWESAGGA QIFRSSNLRL KNFKVYSCRD
2360 2370 2380 2390 2400
FGIDVLESDA NTSVTDSLLL GHFAHKGSLC MSSGIKTPKR WELMVSNTTF
2410 2420 2430 2440 2450
VNFDLINCVA IRTCSDCSQG QGGFTVKTSQ LKFTNSSNLV AFPFPHAAVL
2460 2470 2480 2490 2500
EDLDGSLSGK NRSHILASME TLSASCLVNS SFGRVVHGSA CGGGVLFHRM
2510 2520 2530 2540 2550
SIGLANTPEV SYDLTMTDSR NKTTTVNYVR DTLSNPHGWM ALLLDHETYS
2560 2570 2580 2590 2600
LQSENLWINR SLRYRHKKPS KKINESRSWF FEKINKIDRL LIFKNFFYFL
2610 2620 2630 2640 2650
ASTSAPESAL KWSLPETWQG VEEGWGGYNN TIPGPGDDVL ILPNRTVLVD
2660 2670 2680 2690 2700
TDLPFFKGLY VMGTLDFPVD RSNVLSVACM VIAGGELKVG TLENPLEKEQ
2710 2720 2730 2740 2750
KLLILLRASE GVFCDRMNGI HIDPGTIGVY GKVQLYSAYP KNSWTHLGAD
2760 2770 2780 2790 2800
IASGNERIIV EDAVDWRPHD KIVLSSSSYE PHEAEVLTVK EVKGHHVRIY
2810 2820 2830 2840 2850
ERLKHRHIGS VHVTEDGRHI RLAAEVGLLT RNIQIQPDVS CRGRVFVGSF
2860 2870 2880 2890 2900
RKSSREEFSG VLQLLNVEIQ NFGSPLYSSV EFSNVSAGSW IISSTLHQSC
2910 2920 2930 2940 2950
GGGIHAAANH GVLLNDNIVF GTAGHGIDLE GQAYTVTNNL VVLMTQPAWS
2960 2970 2980 2990 3000
TIWVAGIKVN QVKDINLHGN IVAGSERLGF HIRGRKCSSC ELLWSDNVVH
3010 3020 3030 3040 3050
SSLHGLHLYK ESGLDNCTRI SGFLAFKNFD YGAMLHVENS VEIENITLVD
3060 3070 3080 3090 3100
NTIGLLAVVY VFSAPQNSVR KVQIVLRNSV IVATSSSFDC IQDKVKPHSA
3110 3120 3130 3140 3150
NLTSTDRAPS NPRGGRIGIL WPVFTSEPNQ WPQEPWHKVR NDHSISGIMK
3160 3170 3180 3190 3200
LQDVTFSSFV KSCYSDDLDV CILPNAENSG IVHPITAERT RMLKIKDKNK
3210 3220 3230 3240 3250
FYFPSLQPRK DLGKVVCPEL DCASPRKYLF KDLDGRALGL PPPVSVFPKT
3260 3270 3280 3290 3300
EAEWTASFFN AGTFREEQKC TYQFLMQGFI CKQTDQVVLI LDSADAIWAI
3310 3320 3330 3340 3350
QKLYPVVSVT SGFVDVFSSV NANIPCSTSG SVSTFYSILP TRQITKVCFM
3360 3370 3380 3390 3400
DQTPQVLRFF LLGNKSTSKL LLAVFYHELQ SPHVFLGESF IPPTLVQSAS
3410 3420 3430 3440 3450
LLLNESIGAN YFNIMDNLLY VVLQGEEPIE IRSGVSIHLA LTVMVSVLEK
3460 3470 3480 3490 3500
GWEIVILERL TNFLQIGQNQ IRFIHEMPGH EETLKAIADS RAKRKRNCPT
3510 3520 3530 3540 3550
VTCASHYRRV GQRRPLTMEM NSHRASPPMT VETISKVIII EIGDSPTVRS
3560 3570 3580 3590 3600
TGMISSLSSN KLQKLAHQVI TAQQTGVLEN VLNMTIGALL VTQSKGVIGY
3610 3620 3630 3640 3650
GNTSSFKTGN LIYIRPYALS ILVQPSDGEV GNELPVQPQL VFLDEQNRRV
3660 3670 3680 3690 3700
ESLGPPSEPW TISASLEGAS DSVLKGCTQA ETQDGYVNFY NLAVLISGSN
3710 3720 3730 3740 3750
WHFIFTVTSP PGVNFTARSK PFAVLPVTRK EKSTIILAAS LSSVASWLAL
3760 3770 3780 3790 3800
SCLVGCWLKR SKSRKTKPEE IPESQTNNQN SHIHISSKRR ESQGPKKEDT
3810 3820 3830 3840 3850
VVGEDMRMKV MLGKVNQCPH QLMNGVSRRK VSRHFVREEE AAVPAPGTTS
3860 3870 3880 3890 3900
ITSHGHICAP GAPAQQVYLQ ETGNWKEGQE QFLRYQLAGQ DQLLLLCPDF
3910 3920 3930 3940 3950
RQERQQLPGQ SRLSKQSGSL GLSQEKKASC GATEAFCLHS VHPETIQEQL
Length:3,950
Mass (Da):433,423
Last modified:February 28, 2018 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i74F51BB603E97F01
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CABD030045042 Genomic DNA No translation available.
CABD030045043 Genomic DNA No translation available.
CABD030045044 Genomic DNA No translation available.
CABD030045045 Genomic DNA No translation available.
CABD030045046 Genomic DNA No translation available.
CABD030045047 Genomic DNA No translation available.
CABD030045048 Genomic DNA No translation available.
CABD030045049 Genomic DNA No translation available.
CABD030045050 Genomic DNA No translation available.
CABD030045051 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSGGOT00000011018; ENSGGOP00000010698; ENSGGOG00000010943

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CABD030045042 Genomic DNA No translation available.
CABD030045043 Genomic DNA No translation available.
CABD030045044 Genomic DNA No translation available.
CABD030045045 Genomic DNA No translation available.
CABD030045046 Genomic DNA No translation available.
CABD030045047 Genomic DNA No translation available.
CABD030045048 Genomic DNA No translation available.
CABD030045049 Genomic DNA No translation available.
CABD030045050 Genomic DNA No translation available.
CABD030045051 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi9593.ENSGGOP00000010698

Genome annotation databases

EnsembliENSGGOT00000011018; ENSGGOP00000010698; ENSGGOG00000010943

Phylogenomic databases

GeneTreeiENSGT00940000160697
HOGENOMiCLU_000057_1_0_1
InParanoidiG3R5W5
TreeFamiTF329582

Gene expression databases

BgeeiENSGGOG00000010943 Expressed in adult mammalian kidney and 2 other tissues

Family and domain databases

Gene3Di2.160.20.10, 2 hits
2.60.40.10, 5 hits
InterProiView protein in InterPro
IPR039448 Beta_helix
IPR019316 G8_domain
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
IPR002909 IPT_dom
IPR037524 PA14/GLEYA
IPR006626 PbH1
IPR012334 Pectin_lyas_fold
IPR011050 Pectin_lyase_fold/virulence
IPR028839 PKHD1
PANTHERiPTHR46769:SF1 PTHR46769:SF1, 2 hits
PfamiView protein in Pfam
PF13229 Beta_helix, 1 hit
PF10162 G8, 2 hits
PF01833 TIG, 7 hits
SMARTiView protein in SMART
SM01225 G8, 2 hits
SM00429 IPT, 6 hits
SM00710 PbH1, 10 hits
SUPFAMiSSF51126 SSF51126, 2 hits
SSF81296 SSF81296, 6 hits
PROSITEiView protein in PROSITE
PS51484 G8, 2 hits
PS51820 PA14, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG3R5W5_GORGO
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G3R5W5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: February 28, 2018
Last modified: February 26, 2020
This is version 55 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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