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Protein
Submitted name:

Transmembrane and coiled-coil domains 3

Gene
N/A
Organism
Gorilla gorilla gorilla (Western lowland gorilla)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Transmembrane and coiled-coil domains 3Imported
OrganismiGorilla gorilla gorilla (Western lowland gorilla)Imported
Taxonomic identifieri9595 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeGorilla
Proteomesi
  • UP000001519 Componenti: Chromosome 13

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei280 – 306HelicalSequence analysisAdd BLAST27
Transmembranei318 – 337HelicalSequence analysisAdd BLAST20
Transmembranei357 – 375HelicalSequence analysisAdd BLAST19
Transmembranei428 – 450HelicalSequence analysisAdd BLAST23
Transmembranei456 – 478HelicalSequence analysisAdd BLAST23
Transmembranei499 – 518HelicalSequence analysisAdd BLAST20
Transmembranei554 – 572HelicalSequence analysisAdd BLAST19
Transmembranei579 – 602HelicalSequence analysisAdd BLAST24
Transmembranei608 – 629HelicalSequence analysisAdd BLAST22
Transmembranei641 – 660HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_500345206323 – 677Sequence analysisAdd BLAST655

Expressioni

Gene expression databases

BgeeiENSGGOG00000010596 Expressed in 6 organ(s), highest expression level in cerebellum

Interactioni

Protein-protein interaction databases

STRINGi9593.ENSGGOP00000010341

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini274 – 660Na_H_ExchangerInterPro annotationAdd BLAST387

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili61 – 81Sequence analysisAdd BLAST21
Coiled coili125 – 159Sequence analysisAdd BLAST35
Coiled coili177 – 204Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

GeneTreeiENSGT00390000001394
InParanoidiG3R4X5
OMAiCIEPIRD
OrthoDBiEOG091G03W2
TreeFamiTF329364

Family and domain databases

Gene3Di1.20.1530.20, 1 hit
InterProiView protein in InterPro
IPR006153 Cation/H_exchanger
IPR038770 Na+/solute_symporter_sf
PfamiView protein in Pfam
PF00999 Na_H_Exchanger, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

G3R4X5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKVLGRSFFW VLFPVLPWAV QAVEHEEVAQ RVIKLHRGRG VATMQSRQWV
60 70 80 90 100
RDSCRKLSGL LRQKNAVLNK LKNAIGAVEK DVGLSDEEKL FQVHTFEIFQ
110 120 130 140 150
KELNESENSV FQAVYGLQRA LQGDYKDVVN MKESSRQRLE ALREAAIKEE
160 170 180 190 200
TEYMELLAAE KHQAEALKNM QHQNQSLSML DEILEDVRKA ADRLEEEIEE
210 220 230 240 250
HAFDDNKSVK GVNFEAVLRV EEEEANSKQN ITKREVEDDL GLSMLIDSQN
260 270 280 290 300
NQYILTKPRD STIPRADHHF IKDIVTIGML SLPCGWLCTA IGLPTMFGYI
310 320 330 340 350
ICGVLLGPSG LNSIKSIVQV ETLGEFGVFF TLFLVGLEFS PEKLRKVWKI
360 370 380 390 400
SLQGPCYMTL LMIAFGLLWG HLLRIKPTQS VFISTCLSLS STPLVSRFLM
410 420 430 440 450
GSARGDKEGD IDYSTVLLGM LVTQDVQLGL FMAVMPTLIQ AGASASSSIV
460 470 480 490 500
VEVLRILVLI GQILFSLAAV FLLCLVIKKY LIGPYYRKLH MESKGNKEIL
510 520 530 540 550
ILGISAFIFL MLTVTELLDV SMELGCFLAG ALVSSQGPVV TEEIATSIEP
560 570 580 590 600
IRDFLAIVFF ASIGLHVFPT FVAYELTVLV FLTLSVVVMK FLLAALVLSL
610 620 630 640 650
ILPRSSQYIK WIVSAGLAQV SEFSFVLGSR ARRAGVISRE VYLLILSVTT
660 670
LSLLLAPVLW RAAITRCVPR PERRSSL
Length:677
Mass (Da):75,613
Last modified:November 16, 2011 - v1
Checksum:i2E22BB2952B2ABC0
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2I2Z8B2A0A2I2Z8B2_GORGO
Transmembrane and coiled-coil domai...
544Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CABD030090984 Genomic DNA No translation available.
CABD030090985 Genomic DNA No translation available.
CABD030090986 Genomic DNA No translation available.
CABD030090987 Genomic DNA No translation available.
CABD030090988 Genomic DNA No translation available.
CABD030090989 Genomic DNA No translation available.
CABD030090990 Genomic DNA No translation available.
RefSeqiXP_018895206.1, XM_019039661.1

Genome annotation databases

EnsembliENSGGOT00000010645; ENSGGOP00000010341; ENSGGOG00000010596
GeneIDi101141102

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CABD030090984 Genomic DNA No translation available.
CABD030090985 Genomic DNA No translation available.
CABD030090986 Genomic DNA No translation available.
CABD030090987 Genomic DNA No translation available.
CABD030090988 Genomic DNA No translation available.
CABD030090989 Genomic DNA No translation available.
CABD030090990 Genomic DNA No translation available.
RefSeqiXP_018895206.1, XM_019039661.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9593.ENSGGOP00000010341

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSGGOT00000010645; ENSGGOP00000010341; ENSGGOG00000010596
GeneIDi101141102

Organism-specific databases

CTDi55002

Phylogenomic databases

GeneTreeiENSGT00390000001394
InParanoidiG3R4X5
OMAiCIEPIRD
OrthoDBiEOG091G03W2
TreeFamiTF329364

Gene expression databases

BgeeiENSGGOG00000010596 Expressed in 6 organ(s), highest expression level in cerebellum

Family and domain databases

Gene3Di1.20.1530.20, 1 hit
InterProiView protein in InterPro
IPR006153 Cation/H_exchanger
IPR038770 Na+/solute_symporter_sf
PfamiView protein in Pfam
PF00999 Na_H_Exchanger, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiG3R4X5_GORGO
AccessioniPrimary (citable) accession number: G3R4X5
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: October 10, 2018
This is version 40 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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