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Protein

Aminopeptidase

Gene
N/A
Organism
Gorilla gorilla gorilla (Western lowland gorilla)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cofactori

Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminopeptidaseUniRule annotation, Hydrolase, MetalloproteaseUniRule annotation, Protease
LigandMetal-bindingUniRule annotation, ZincUniRule annotation

Protein family/group databases

MEROPSiM01.018

Names & Taxonomyi

Protein namesi
Recommended name:
AminopeptidaseUniRule annotation (EC:3.4.11.-UniRule annotation)
OrganismiGorilla gorilla gorilla (Western lowland gorilla)Imported
Taxonomic identifieri9595 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeGorilla
Proteomesi
  • UP000001519 Componenti: Chromosome 5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 32Sequence analysisAdd BLAST32
ChainiPRO_500345202033 – 948AminopeptidaseSequence analysisAdd BLAST916

Expressioni

Gene expression databases

BgeeiENSGGOG00000009305 Expressed in 6 organ(s), highest expression level in liver

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9593.ENSGGOP00000009097

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini264 – 524Peptidase_M1InterPro annotationAdd BLAST261
Domaini597 – 916ERAP1_CInterPro annotationAdd BLAST320

Sequence similaritiesi

Belongs to the peptidase M1 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

GeneTreeiENSGT00760000119082
InParanoidiG3R1L9
KOiK09604
OMAiDTGYLWH
OrthoDBiEOG091G01GH
TreeFamiTF300395

Family and domain databases

CDDicd09601 M1_APN_2, 1 hit
InterProiView protein in InterPro
IPR033520 ERAP1
IPR024571 ERAP1-like_C_dom
IPR034016 M1_APN-typ
IPR001930 Peptidase_M1
IPR014782 Peptidase_M1_N
PANTHERiPTHR11533 PTHR11533, 1 hit
PTHR11533:SF156 PTHR11533:SF156, 1 hit
PfamiView protein in Pfam
PF11838 ERAP1_C, 1 hit
PF01433 Peptidase_M1, 1 hit
PRINTSiPR00756 ALADIPTASE

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

G3R1L9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVFLPLKWSL ATMSFLLSSL LALLTVSTPS WCQSTEASPK GSGGTPFPWN
60 70 80 90 100
KIRLPEYVIP VHYDLLIHAN LTTLTFWGTT KVEITASQPT STIILHSHHL
110 120 130 140 150
QIFRATLRKG AGERLSEEPL QVLEHPAQEQ IALLAPEPLL VGLPYTVVIH
160 170 180 190 200
YAGNLSETFH GFYKSTYRTK EGELRLLAST QFQPTAARMA FPCFDEPAFK
210 220 230 240 250
ASFSIKIRRE PRHLAISNMP LVKSVTVAEG LIEDHFDVTV KMSTYLVAFI
260 270 280 290 300
ISDFESVSKI TKSGVKVSVY AVPDKINQAD YALDAAVTLL EFYEDYFGIP
310 320 330 340 350
YPLPKQDLAA IPDFQSGAME NWGLTTYRES ALLFDAEKSS ASSKLGITMT
360 370 380 390 400
VAHELAHQWF GNLVTMEWWN DLWLNEGFAK FMEFVSVSVT HPELKVGDYF
410 420 430 440 450
FGKCFDAMEV DALNSSHPVS TPVENPAQIR EMFDDVSYDK GACILNMLRE
460 470 480 490 500
YLSADAFKSG IVQYLQKHSY KNTKNEDLWD SMASICPTDG VKGMDGFCSR
510 520 530 540 550
SQHSSSSSHW HQEGLDVKTM MNTWTLQKGF PLITITVRGR NVHMKQEHYM
560 570 580 590 600
KGSDGAPDTG YLWHVPLTFI TSKSDMVHRF LLKTKTDVLI LPEEVEWIKF
610 620 630 640 650
NVGMNGYYIV HYEDDGWDSL TGLLKGTHTA VSSNDRASLI NNAFQLVSIG
660 670 680 690 700
KLSIEKALDL SLYLKHETEI MPVFQGLNEL IPMYKLMEKR DMNEVETQFK
710 720 730 740 750
AFLIRLLRDL IDKQTWTDEG SVSERMLRSQ LLLLACVHNY QPCVQRAEGY
760 770 780 790 800
FRKWKESNGN LSLPVDVTLA VFDVGAQSTE GWDFLYSKYQ FSLSSTEKSQ
810 820 830 840 850
IEFALCRTQN KEKLQWLLDE SFKGDKIKTQ EFPQILTLIG RNPVGYPLAW
860 870 880 890 900
QFLRKNWNKL VQKFELGSSS IAHMVMGTTN QFSTSTWLEE VKGFFSSLKE
910 920 930 940
NGSQLRCVQQ TIETIEENIG WMDKNFDKIR VWLQSEKLEH DPEADATG
Length:948
Mass (Da):107,647
Last modified:November 16, 2011 - v1
Checksum:i98E773C35791F8CE
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2I2Y2Y2A0A2I2Y2Y2_GORGO
Endoplasmic reticulum aminopeptidas...
548Annotation score:
A0A2I2YF90A0A2I2YF90_GORGO
Endoplasmic reticulum aminopeptidas...
654Annotation score:
A0A2I2ZPS5A0A2I2ZPS5_GORGO
Endoplasmic reticulum aminopeptidas...
602Annotation score:
A0A2I2ZFH4A0A2I2ZFH4_GORGO
Endoplasmic reticulum aminopeptidas...
717Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CABD030039784 Genomic DNA No translation available.
RefSeqiXP_018882978.1, XM_019027433.1

Genome annotation databases

EnsembliENSGGOT00000009350; ENSGGOP00000009097; ENSGGOG00000009305
GeneIDi101135527
KEGGiggo:101135527

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CABD030039784 Genomic DNA No translation available.
RefSeqiXP_018882978.1, XM_019027433.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9593.ENSGGOP00000009097

Protein family/group databases

MEROPSiM01.018

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSGGOT00000009350; ENSGGOP00000009097; ENSGGOG00000009305
GeneIDi101135527
KEGGiggo:101135527

Organism-specific databases

CTDi51752

Phylogenomic databases

GeneTreeiENSGT00760000119082
InParanoidiG3R1L9
KOiK09604
OMAiDTGYLWH
OrthoDBiEOG091G01GH
TreeFamiTF300395

Gene expression databases

BgeeiENSGGOG00000009305 Expressed in 6 organ(s), highest expression level in liver

Family and domain databases

CDDicd09601 M1_APN_2, 1 hit
InterProiView protein in InterPro
IPR033520 ERAP1
IPR024571 ERAP1-like_C_dom
IPR034016 M1_APN-typ
IPR001930 Peptidase_M1
IPR014782 Peptidase_M1_N
PANTHERiPTHR11533 PTHR11533, 1 hit
PTHR11533:SF156 PTHR11533:SF156, 1 hit
PfamiView protein in Pfam
PF11838 ERAP1_C, 1 hit
PF01433 Peptidase_M1, 1 hit
PRINTSiPR00756 ALADIPTASE
ProtoNetiSearch...

Entry informationi

Entry nameiG3R1L9_GORGO
AccessioniPrimary (citable) accession number: G3R1L9
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: October 10, 2018
This is version 45 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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