UniProtKB - G3QVG4 (G3QVG4_GORGO)
Protein
Submitted name:
Nuclear factor of activated T cells 1
Gene
NFATC1
Organism
Gorilla gorilla gorilla (Western lowland gorilla)
Status
Functioni
GO - Molecular functioni
- DNA binding Source: UniProtKB-KW
- DNA-binding transcription factor activity Source: InterPro
Keywordsi
Molecular function | ActivatorARBA annotation, DNA-bindingARBA annotation |
Biological process | Transcription, Transcription regulationARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Nuclear factor of activated T cells 1Imported |
Gene namesi | Name:NFATC1Imported |
Organismi | Gorilla gorilla gorilla (Western lowland gorilla)Imported |
Taxonomic identifieri | 9595 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Gorilla › |
Proteomesi |
|
Expressioni
Gene expression databases
Bgeei | ENSGGOG00000006879, Expressed in heart and 6 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 393 – 575 | RHDInterPro annotationAdd BLAST | 183 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 183 – 281 | DisorderedSequence analysisAdd BLAST | 99 | |
Regioni | 770 – 894 | DisorderedSequence analysisAdd BLAST | 125 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 216 – 237 | PolarSequence analysisAdd BLAST | 22 | |
Compositional biasi | 793 – 808 | Pro-richSequence analysisAdd BLAST | 16 | |
Compositional biasi | 825 – 859 | Pro-richSequence analysisAdd BLAST | 35 | |
Compositional biasi | 862 – 881 | PolyampholyteSequence analysisAdd BLAST | 20 |
Phylogenomic databases
eggNOGi | ENOG502QTX8, Eukaryota |
GeneTreei | ENSGT00940000157616 |
HOGENOMi | CLU_010185_1_0_1 |
InParanoidi | G3QVG4 |
TreeFami | TF326480 |
Family and domain databases
Gene3Di | 2.60.40.10, 1 hit 2.60.40.340, 1 hit |
InterProi | View protein in InterPro IPR013783, Ig-like_fold IPR014756, Ig_E-set IPR002909, IPT_dom IPR008366, NFAT IPR015647, NFAT1 IPR008967, p53-like_TF_DNA-bd IPR032397, RHD_dimer IPR011539, RHD_DNA_bind_dom IPR037059, RHD_DNA_bind_dom_sf |
PANTHERi | PTHR12533, PTHR12533, 1 hit PTHR12533:SF5, PTHR12533:SF5, 1 hit |
Pfami | View protein in Pfam PF16179, RHD_dimer, 1 hit PF00554, RHD_DNA_bind, 1 hit |
PRINTSi | PR01789, NUCFACTORATC |
SMARTi | View protein in SMART SM00429, IPT, 1 hit |
SUPFAMi | SSF49417, SSF49417, 1 hit SSF81296, SSF81296, 1 hit |
PROSITEi | View protein in PROSITE PS50254, REL_2, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
G3QVG4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
CRRLRGSRPL EGISLRWGRR DWGLAKHYGY ASSNVSPALP LPTAHSTLPA
60 70 80 90 100
PCHNLQTSTP GIIPPADHPS GYGAALDGGP AGYFLSSGHT RPDGAPALES
110 120 130 140 150
PRIEITSCLG LYHNNNQFFH DVEVEDVLPS SKRSPSTATL SLPSLEAYRD
160 170 180 190 200
PSCLSPASSL SSRSCNSEAS SYESNYSYPY ASPQTSPWQS PCVSPKTTDP
210 220 230 240 250
EEGFPRGLGA CTLLGSPRHS PSTSPRASVT EESWLGARSS RPASPCNKRK
260 270 280 290 300
YSLNGRQPPY SPHHSPTPSP HGSPRVSVTD DSWLGNTTQY TSSAIVAAIN
310 320 330 340 350
ALTTDSSLDL GDGVPVKSRK TTLEQPPSVA LKVEPVGEDL GSPPPPADFA
360 370 380 390 400
PEDFSSFQHI RKGGFCDQYL AVPQHPYQWA KPKPLSPTSY MSPTLPALDW
410 420 430 440 450
QLPSHSGPYE LRIEVQPKSH HRAHYETEGS RGAVKASAGG HPIVQLHGYL
460 470 480 490 500
ENEPLMLQLF IGTADDRLLR PHAFYQVHRI TGKTVSTTSH EAILSNTKVL
510 520 530 540 550
EIPLLPENSM RAVIDCAGIL KLRNSDIELR KGETDIGRKN TRVRLVFRVH
560 570 580 590 600
VPQPSGRTLS LQVASNPIEC SQRSAQELPL VEKQSTDSYP VVGGKKMVLS
610 620 630 640 650
GHNFLQDSKV IFVEKAPDGH HVWEMEAKTD RDLCKPNSLV VEIPPFRNQR
660 670 680 690 700
ITSPVHVSFY VCNGKRKRSQ YQRFTYLPAN VPIIKTEPTD DYEPAPTCGP
710 720 730 740 750
VSQGLSPLPR PYYSQQLAMP PDPSSCLVAG FPPCPQRSTL MPAAPGVSPK
760 770 780 790 800
LHDLSPAAYT KGVASPGHCH LGLPQPAGEA PAIQDVPRPV ATHPGSPGQP
810 820 830 840 850
PPALLPQQVS APPSSSCPPG LEHSLCPSSP SPPLPPATQE PTCLQPCSPA
860 870 880 890 900
CPPATGRPQH PPSTVRRDES PTARPRLLPE AHEDGSPNLA PIPVTVKREP
910 920
EELDQLYLDD GGWEMLRNSL STCHALSQL
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A2I2ZWX0 | A0A2I2ZWX0_GORGO | Nuclear factor of activated T cells... | NFATC1 | 948 | Annotation score: | ||
A0A2I2Y7H5 | A0A2I2Y7H5_GORGO | Nuclear factor of activated T cells... | NFATC1 | 670 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CABD030110347 Genomic DNA No translation available. CABD030110348 Genomic DNA No translation available. CABD030110349 Genomic DNA No translation available. CABD030110350 Genomic DNA No translation available. CABD030110351 Genomic DNA No translation available. CABD030110352 Genomic DNA No translation available. CABD030110353 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENSGGOT00000006910; ENSGGOP00000006733; ENSGGOG00000006879 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CABD030110347 Genomic DNA No translation available. CABD030110348 Genomic DNA No translation available. CABD030110349 Genomic DNA No translation available. CABD030110350 Genomic DNA No translation available. CABD030110351 Genomic DNA No translation available. CABD030110352 Genomic DNA No translation available. CABD030110353 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 9593.ENSGGOP00000006733 |
Genome annotation databases
Ensembli | ENSGGOT00000006910; ENSGGOP00000006733; ENSGGOG00000006879 |
Phylogenomic databases
eggNOGi | ENOG502QTX8, Eukaryota |
GeneTreei | ENSGT00940000157616 |
HOGENOMi | CLU_010185_1_0_1 |
InParanoidi | G3QVG4 |
TreeFami | TF326480 |
Gene expression databases
Bgeei | ENSGGOG00000006879, Expressed in heart and 6 other tissues |
Family and domain databases
Gene3Di | 2.60.40.10, 1 hit 2.60.40.340, 1 hit |
InterProi | View protein in InterPro IPR013783, Ig-like_fold IPR014756, Ig_E-set IPR002909, IPT_dom IPR008366, NFAT IPR015647, NFAT1 IPR008967, p53-like_TF_DNA-bd IPR032397, RHD_dimer IPR011539, RHD_DNA_bind_dom IPR037059, RHD_DNA_bind_dom_sf |
PANTHERi | PTHR12533, PTHR12533, 1 hit PTHR12533:SF5, PTHR12533:SF5, 1 hit |
Pfami | View protein in Pfam PF16179, RHD_dimer, 1 hit PF00554, RHD_DNA_bind, 1 hit |
PRINTSi | PR01789, NUCFACTORATC |
SMARTi | View protein in SMART SM00429, IPT, 1 hit |
SUPFAMi | SSF49417, SSF49417, 1 hit SSF81296, SSF81296, 1 hit |
PROSITEi | View protein in PROSITE PS50254, REL_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | G3QVG4_GORGO | |
Accessioni | G3QVG4Primary (citable) accession number: G3QVG4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 16, 2011 |
Last sequence update: | February 28, 2018 | |
Last modified: | December 2, 2020 | |
This is version 54 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |