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Protein
Submitted name:

Neurotrypsin

Gene

PRSS12

Organism
Gorilla gorilla gorilla (Western lowland gorilla)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protease, Serine proteaseUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
NeurotrypsinImported
Gene namesi
Name:PRSS12Imported
OrganismiGorilla gorilla gorilla (Western lowland gorilla)Imported
Taxonomic identifieri9595 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeGorilla
Proteomesi
  • UP000001519 Componenti: Chromosome 4

Subcellular locationi

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi196 ↔ 260PROSITE-ProRule annotation
Disulfide bondi209 ↔ 270PROSITE-ProRule annotation
Disulfide bondi240 ↔ 250PROSITE-ProRule annotation
Disulfide bondi306 ↔ 370PROSITE-ProRule annotation
Disulfide bondi319 ↔ 380PROSITE-ProRule annotation
Disulfide bondi350 ↔ 360PROSITE-ProRule annotation
Disulfide bondi456 ↔ 466PROSITE-ProRule annotation
Disulfide bondi526 ↔ 590PROSITE-ProRule annotation
Disulfide bondi539 ↔ 600PROSITE-ProRule annotation
Disulfide bondi570 ↔ 580PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSGGOG00000002810

Structurei

3D structure databases

ProteinModelPortaliG3QK11
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase S1 family.SAAS annotation

Keywords - Domaini

KringlePROSITE-ProRule annotationSAAS annotation, SignalSequence analysis

Phylogenomic databases

GeneTreeiENSGT00900000140803
KOiK09624
OMAiCIKQDIG
OrthoDBiEOG091G0DF7
TreeFamiTF329295

Family and domain databases

CDDicd00190 Tryp_SPc, 1 hit
Gene3Di2.40.20.10, 1 hit
3.10.250.10, 4 hits
InterProiView protein in InterPro
IPR000001 Kringle
IPR013806 Kringle-like
IPR018056 Kringle_CS
IPR038178 Kringle_sf
IPR009003 Peptidase_S1_PA
IPR001314 Peptidase_S1A
IPR001190 SRCR
IPR017448 SRCR-like_dom
IPR036772 SRCR-like_dom_sf
IPR001254 Trypsin_dom
IPR018114 TRYPSIN_HIS
IPR033116 TRYPSIN_SER
PfamiView protein in Pfam
PF00051 Kringle, 1 hit
PF00530 SRCR, 4 hits
PF00089 Trypsin, 1 hit
PRINTSiPR00722 CHYMOTRYPSIN
PR00258 SPERACTRCPTR
SMARTiView protein in SMART
SM00130 KR, 1 hit
SM00202 SR, 4 hits
SM00020 Tryp_SPc, 1 hit
SUPFAMiSSF50494 SSF50494, 1 hit
SSF56487 SSF56487, 4 hits
SSF57440 SSF57440, 1 hit
PROSITEiView protein in PROSITE
PS00021 KRINGLE_1, 1 hit
PS50070 KRINGLE_2, 1 hit
PS00420 SRCR_1, 3 hits
PS50287 SRCR_2, 4 hits
PS50240 TRYPSIN_DOM, 1 hit
PS00134 TRYPSIN_HIS, 1 hit
PS00135 TRYPSIN_SER, 1 hit

Sequencei

Sequence statusi: Complete.

G3QK11-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLARFVLAL MLGALPEVVG FDSVLNDSLH HSHRHSPPPG PHYSSYYLPT
60 70 80 90 100
QQRPPRTRPP PPLPRFPRPP RALPAQRPHA LQAGHTPRPH PWGCPAGEPW
110 120 130 140 150
VSVTDFGARC LRWAEVPPFL ERSPPASWAQ LRGQRHNFCR SPDGAGRPWC
160 170 180 190 200
FYGDARGKVD WGYCDCRHGS VRLRGGKNEF EGTVEVYASG VWGTVCSSHW
210 220 230 240 250
DDSDASVICH QLQLGGKGIA KQTPFSGLGL IPVYWSNVRC RGDEENILLC
260 270 280 290 300
EKDIWQGGVC PQKMAAAVTC SFSHGPTFPI IRLAGGSSVH EGRVELYHAG
310 320 330 340 350
QWGTVCDDQW DDADAEVICR QLGLSGIAKA WHQAYFGEGS GPVMLDEVRC
360 370 380 390 400
TGNELSIEQC PKSSWGEHNC GHKEDAGVSC TPLTDGVIRL AGGKGSHEGR
410 420 430 440 450
LEVYYRGQWG TVCDDGWTEL NTYVVCRQLG FKYGKQASAN HFEESTGPIW
460 470 480 490 500
LDDVSCSGKE TRFLQCSRRQ WGRHDCSHRE DVSIACYPGG EGHRLSLGFP
510 520 530 540 550
VRLMDGENKK EGRVEVFING QWGTICDDGW TDKDAAVICR QLGYKGPARA
560 570 580 590 600
RTMAYFGEGK GPIHVDNVKC TGNERSLADC IKQDIGRHNC RHSEDAGVIC
610 620 630 640 650
DYFGKKASGN SNKESLSSVC GLRLLHRRQK RIIGGKNSLR GGWPWQVSLR
660 670 680 690 700
LKSYHGDGRL LCGATLLSSC WVLTAAHCFK RYGNSTRNYA VRVGDYHTLV
710 720 730 740 750
PEEFEEEIGV QQIVIHREYR PDSSDYDIAL VRLQGPEEQC ARFSSHVLPA
760 770 780 790 800
CLPLWRERPQ KTASNCYITG WGDTGRAYSR TLQQAAIPLL PKRFCEERYK
810 820 830 840 850
GRFTGRMLCA GNLHEHKRVD SCQGDSGGPL MCERPGESWV VYGVTSWGYG
860 870
CGVKDSPGVY TKVSAFVPWI KSVTKL
Length:876
Mass (Da):97,249
Last modified:February 28, 2018 - v2
Checksum:iC3371C741FEAE181
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CABD030032962 Genomic DNA No translation available.
RefSeqiXP_004040363.2, XM_004040315.2

Genome annotation databases

EnsembliENSGGOT00000002830; ENSGGOP00000002772; ENSGGOG00000002810
GeneIDi101143452
KEGGiggo:101143452

Similar proteinsi

Entry informationi

Entry nameiG3QK11_GORGO
AccessioniPrimary (citable) accession number: G3QK11
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: February 28, 2018
Last modified: July 18, 2018
This is version 58 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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