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Entry version 48 (02 Jun 2021)
Sequence version 1 (16 Nov 2011)
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Protein
Submitted name:

AT rich interactive domain 2 (ARID, RFX-like)

Gene
N/A
Organism
Gasterosteus aculeatus (Three-spined stickleback)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
AT rich interactive domain 2 (ARID, RFX-like)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiGasterosteus aculeatus (Three-spined stickleback)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri69293 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataEupercariaPerciformesCottioideiGasterostealesGasterosteidaeGasterosteus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000007635 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
69293.ENSGACP00000025804

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini13 – 105ARIDInterPro annotationAdd BLAST93
Domaini523 – 602RFX-type winged-helixInterPro annotationAdd BLAST80

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni620 – 648DisorderedSequence analysisAdd BLAST29
Regioni701 – 723DisorderedSequence analysisAdd BLAST23
Regioni926 – 983DisorderedSequence analysisAdd BLAST58
Regioni1203 – 1257DisorderedSequence analysisAdd BLAST55
Regioni1278 – 1365DisorderedSequence analysisAdd BLAST88
Regioni1446 – 1490DisorderedSequence analysisAdd BLAST45
Regioni1567 – 1595DisorderedSequence analysisAdd BLAST29

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi703 – 717Polar residuesSequence analysisAdd BLAST15
Compositional biasi937 – 983Polar residuesSequence analysisAdd BLAST47
Compositional biasi1349 – 1365Polar residuesSequence analysisAdd BLAST17
Compositional biasi1567 – 1585Polar residuesSequence analysisAdd BLAST19

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2312, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000016138

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
G3Q7E4

Identification of Orthologs from Complete Genome Data

More...
OMAi
ICDWRNC

TreeFam database of animal gene trees

More...
TreeFami
TF106406

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.10.10, 1 hit
1.10.150.60, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001606, ARID_dom
IPR036431, ARID_dom_sf
IPR016024, ARM-type_fold
IPR003150, DNA-bd_RFX
IPR036388, WH-like_DNA-bd_sf
IPR036390, WH_DNA-bd_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01388, ARID, 1 hit
PF02257, RFX_DNA_binding, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00501, BRIGHT, 1 hit
SM00355, ZnF_C2H2, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46774, SSF46774, 1 hit
SSF46785, SSF46785, 1 hit
SSF48371, SSF48371, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51011, ARID, 1 hit
PS51526, RFX_DBD, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

G3Q7E4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASSTGKNLL DQRRKGQAFL DELRQFHQSR GSPFRKIPVA GGKELDLNAL
60 70 80 90 100
YVRVVSLGGF AKVSDKNQWV ELGDEFHFPR SCSNAAFALK QYYLRYLEKY
110 120 130 140 150
EKVHHFGEDD EEAQPGNPKA SLPIGAIPSS YNYQQHVVSD YLRQSYGLSS
160 170 180 190 200
DFVPPCDYNK LVLSLLSGLP NEVDFAVNVC TLLSNESKHA MQLDKDPKLV
210 220 230 240 250
TLLLAHAGVF DDSLGSFSGV FGTDWKEKSS RDFVRFWKEV VEDVEVRELI
260 270 280 290 300
WDKNSPAKDG TSSEERWQSL FHPPRNQGIG DMEAQRVLQI AVILRNLSFE
310 320 330 340 350
EANVKLLAAN RTCLRFLLLC AHCNLISLRQ LGLDTLGNVA AELQLDPVDF
360 370 380 390 400
RTTHLIFHTI TKCLMSRDRF LKMRAMEILG NLSKAEDNGV LICEYVDQDS
410 420 430 440 450
YREVIMLLTL PDLMLLMASL EVLYLLAQLG DIPCSKMASV DRSIDLLVRL
460 470 480 490 500
VSVDLHTFGP DALTAVRLIE HQASADQAAE VRPQLVEQVP AAVQGAAAPV
510 520 530 540 550
TRVPVQSTQP PAGIVELDGE KFTLQWLNAH FETNAEGSVS RSEMYSEYLA
560 570 580 590 600
TCSKMGRSNI LNSTGFLKCL RTVFPSHTMR RQEEAKANGQ VHILLVGLRR
610 620 630 640 650
RAIPLPIQLY YQQQSAAAAQ TPAARLEAPG DPPAPPPGRT SLGNKGIQDN
660 670 680 690 700
SLNEGAYAGT LRGRLLIHVR AQKTFGRLLC LKPPSLGPQF VRVMGHGLSA
710 720 730 740 750
TGAAPPSAST AQEPPHVSHP TVSRHPVAMQ ASLQLPPNPL AALQQQPGRP
760 770 780 790 800
GPVVQIAASA PAAQNPAAQQ HSPMLPTGPP VTLFQQVPQG HILTARVHGV
810 820 830 840 850
CPPITQHLAG PQGGALQAEP PCAASTPSSS IHVGAGHTFS IAGVTNSQGS
860 870 880 890 900
RGAFQNIAPK PAPSHLGAPA ATIAPPNQLP QPPQQSQSLV IVGPNPQQNP
910 920 930 940 950
AYAPAMHQIV LANPSAIPGP QTIQIAGHPG AASSPCPPPA SHSNTQVQAN
960 970 980 990 1000
QTVSHALSMK RHQQQLQLMS QTPPSQPTST ESSLIKQLLL PKRGPSTPGG
1010 1020 1030 1040 1050
KLILPAPQVP PPNSTMASSP QVIYQTSYST QNPSPQPQQL NVQLVPGQLP
1060 1070 1080 1090 1100
AAGAPTLQTV QLLPGQLIST GSPGAATIIQ GPTSAGVTFT VVPTTGFTTS
1110 1120 1130 1140 1150
TAAVSTGAVA PGVPPPPFLA ASVPHDAPAS PTPPPLPAPL RGDKIICQKE
1160 1170 1180 1190 1200
EEAKDATGLH IHERKIEVME NSSLAEGDSN GKPSNGDVAA GAKLLNGGKC
1210 1220 1230 1240 1250
MESNLPPYNS GKSQGGLNGP ATEGHPANGK QALSSIPNTP LEGNPDPKKT
1260 1270 1280 1290 1300
LVNGVCDFDR SDSGGNLNKN IPNHIASKQY LGNGDVGPSE KSRGSDLPLP
1310 1320 1330 1340 1350
SPPLPQPDTS KAQQAERLVN GPQAAGNRPP SELTNGPLVP GHGVPALRQQ
1360 1370 1380 1390 1400
PLPNSTLPST VTVNSAGAPA NGVACEARGL KRPAESEERG GAAPSGIPNK
1410 1420 1430 1440 1450
VGVRIITISD PNNAGSSATM VAVPAGTDPS TVAKVAIENA TQQRNCLPTM
1460 1470 1480 1490 1500
APGSTTFVPP QPTVTPPPGN HSPHLSAQQG PAAPPEQSRK AGQNFKCLWQ
1510 1520 1530 1540 1550
SCKRWFETPS RVFYHAATQH GGKGLYGGHC QWEGCEPFPR QRLSFITHLQ
1560 1570 1580 1590 1600
DKHCSREALL AGLKLEEQQA QSPNQTSSQT PPTAGSTPTP RAPKAIVNHP
1610 1620 1630 1640 1650
SAALMALRRG SRNLVFRDFT DDKEGPVTKH IRLTAALTLK NIAKHSDCGR
1660 1670 1680
MLVKRHETHL SVLALSNMEV STTLAKCLYE LTRSLQA
Length:1,687
Mass (Da):179,744
Last modified:November 16, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD551DEBA5DAD5EAD
GO

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSGACT00000025855; ENSGACP00000025804; ENSGACG00000019522

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi69293.ENSGACP00000025804

Genome annotation databases

EnsembliENSGACT00000025855; ENSGACP00000025804; ENSGACG00000019522

Phylogenomic databases

eggNOGiKOG2312, Eukaryota
GeneTreeiENSGT00390000016138
InParanoidiG3Q7E4
OMAiICDWRNC
TreeFamiTF106406

Family and domain databases

Gene3Di1.10.10.10, 1 hit
1.10.150.60, 1 hit
InterProiView protein in InterPro
IPR001606, ARID_dom
IPR036431, ARID_dom_sf
IPR016024, ARM-type_fold
IPR003150, DNA-bd_RFX
IPR036388, WH-like_DNA-bd_sf
IPR036390, WH_DNA-bd_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF01388, ARID, 1 hit
PF02257, RFX_DNA_binding, 1 hit
SMARTiView protein in SMART
SM00501, BRIGHT, 1 hit
SM00355, ZnF_C2H2, 2 hits
SUPFAMiSSF46774, SSF46774, 1 hit
SSF46785, SSF46785, 1 hit
SSF48371, SSF48371, 1 hit
PROSITEiView protein in PROSITE
PS51011, ARID, 1 hit
PS51526, RFX_DBD, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG3Q7E4_GASAC
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G3Q7E4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: June 2, 2021
This is version 48 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
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