UniProtKB - G3PRX4 (G3PRX4_GASAC)
Protein
Submitted name:
CBFA2/RUNX1 partner transcriptional co-repressor 3
Gene
N/A
Organism
Gasterosteus aculeatus (Three-spined stickleback)
Status
Functioni
GO - Molecular functioni
- metal ion binding Source: UniProtKB-KW
- transcription corepressor activity Source: InterPro
GO - Biological processi
- negative regulation of transcription, DNA-templated Source: InterPro
- transcription, DNA-templated Source: InterPro
Keywordsi
Molecular function | RepressorARBA annotation |
Biological process | Transcription, Transcription regulationARBA annotation |
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: CBFA2/RUNX1 partner transcriptional co-repressor 3Imported |
Organismi | Gasterosteus aculeatus (Three-spined stickleback)Imported |
Taxonomic identifieri | 69293 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Neoteleostei › Acanthomorphata › Eupercaria › Perciformes › Cottioidei › Gasterosteales › Gasterosteidae › Gasterosteus |
Proteomesi |
|
Subcellular locationi
Nucleus
- nucleus Source: UniProtKB-KW
Keywords - Cellular componenti
NucleusARBA annotationFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 111 – 206 | TAFHInterPro annotationAdd BLAST | 96 | |
Domaini | 511 – 547 | MYND-typeInterPro annotationAdd BLAST | 37 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 43 | DisorderedSequence analysisAdd BLAST | 43 | |
Regioni | 74 – 104 | DisorderedSequence analysisAdd BLAST | 31 | |
Regioni | 227 – 293 | DisorderedSequence analysisAdd BLAST | 67 | |
Regioni | 558 – 601 | DisorderedSequence analysisAdd BLAST | 44 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 315 – 335 | Sequence analysisAdd BLAST | 21 | |
Coiled coili | 442 – 492 | Sequence analysisAdd BLAST | 51 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 28 – 43 | PolarSequence analysisAdd BLAST | 16 | |
Compositional biasi | 227 – 251 | PolyampholyteSequence analysisAdd BLAST | 25 | |
Compositional biasi | 267 – 293 | Pro-richSequence analysisAdd BLAST | 27 | |
Compositional biasi | 572 – 601 | PolarSequence analysisAdd BLAST | 30 |
Keywords - Domaini
Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationARBA annotationPhylogenomic databases
eggNOGi | ENOG502QTD6, Eukaryota |
GeneTreei | ENSGT00950000183176 |
InParanoidi | G3PRX4 |
OMAi | AHREFMP |
TreeFami | TF106303 |
Family and domain databases
Gene3Di | 1.20.120.1110, 1 hit |
InterProi | View protein in InterPro IPR013289, CBFA2T1/2/3 IPR014896, NHR2 IPR037249, TAFH/NHR1_dom_sf IPR003894, TAFH_NHR1 IPR002893, Znf_MYND |
PANTHERi | PTHR10379, PTHR10379, 1 hit |
Pfami | View protein in Pfam PF08788, NHR2, 1 hit PF07531, TAFH, 1 hit PF01753, zf-MYND, 1 hit |
PRINTSi | PR01875, ETOFAMILY |
SMARTi | View protein in SMART SM00549, TAFH, 1 hit |
SUPFAMi | SSF158553, SSF158553, 1 hit |
PROSITEi | View protein in PROSITE PS51119, TAFH, 1 hit PS01360, ZF_MYND_1, 1 hit PS50865, ZF_MYND_2, 1 hit |
i Sequence
Sequence statusi: Complete.
G3PRX4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPDSPADVKT QPRSTPPTMP PPPPAVSQAT NRNASFTPAT SKSTLSKTRI
60 70 80 90 100
QVLHYIGELV WAGITILLNG SSHSPTSLNG APSTPNGFSN GPAMSSTASL
110 120 130 140 150
SNQQLPPACG ARQLCKLKRF LTTLQQFGND ISPEIGERVR SLVLGLVNST
160 170 180 190 200
LTIEEFHSKL HEATNFPLRP FVIPFLKANL PLLQRELLHC ARLAKQTPAQ
210 220 230 240 250
YLAQHEQLLL DANASSPLDS SEIMLEMNDH GKRRTPDRTK DSSEHPDHMA
260 270 280 290 300
KRPCTISPSQ RFSPSTGLPA HPPPNGLPTH PPNGLPHPPN PQVGPQHYRL
310 320 330 340 350
EDMALAHQYR DAYRHNEQRD ARDRLRQTVH GARQEEVIDH RLTDREWAEE
360 370 380 390 400
WKHLDNLLNC IMDMVEKTRR SLTVLRRCQE ADREEMNHWI RRYSDVEEMK
410 420 430 440 450
KGGSNGQHCH NSSSNTELPR LQIHRDFLHR PPSGYLPEEI WRKAAEEAVN
460 470 480 490 500
EVKRQAMSEL QKAVSDAERK AHEMISAERS KMERALAEAK RQASEDALTV
510 520 530 540 550
INQQEDSSES CWNCGRKASE TCSGCNTARY CGSFCQHKDW EKHHHVCGQG
560 570 580 590 600
LQGMPGGQVS VAGGAGGGSG SVSASPKESS SSSVSRSTTP ATPALLDATS
R
Genome annotation databases
Ensembli | ENSGACT00000020399; ENSGACP00000020360; ENSGACG00000015432 |
Similar proteinsi
Cross-referencesi
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 69293.ENSGACP00000020360 |
Genome annotation databases
Ensembli | ENSGACT00000020399; ENSGACP00000020360; ENSGACG00000015432 |
Phylogenomic databases
eggNOGi | ENOG502QTD6, Eukaryota |
GeneTreei | ENSGT00950000183176 |
InParanoidi | G3PRX4 |
OMAi | AHREFMP |
TreeFami | TF106303 |
Family and domain databases
Gene3Di | 1.20.120.1110, 1 hit |
InterProi | View protein in InterPro IPR013289, CBFA2T1/2/3 IPR014896, NHR2 IPR037249, TAFH/NHR1_dom_sf IPR003894, TAFH_NHR1 IPR002893, Znf_MYND |
PANTHERi | PTHR10379, PTHR10379, 1 hit |
Pfami | View protein in Pfam PF08788, NHR2, 1 hit PF07531, TAFH, 1 hit PF01753, zf-MYND, 1 hit |
PRINTSi | PR01875, ETOFAMILY |
SMARTi | View protein in SMART SM00549, TAFH, 1 hit |
SUPFAMi | SSF158553, SSF158553, 1 hit |
PROSITEi | View protein in PROSITE PS51119, TAFH, 1 hit PS01360, ZF_MYND_1, 1 hit PS50865, ZF_MYND_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | G3PRX4_GASAC | |
Accessioni | G3PRX4Primary (citable) accession number: G3PRX4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 16, 2011 |
Last sequence update: | November 16, 2011 | |
Last modified: | December 2, 2020 | |
This is version 56 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |