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Entry version 55 (07 Oct 2020)
Sequence version 1 (16 Nov 2011)
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Protein
Submitted name:

Arginine-glutamic acid dipeptide (RE) repeats b

Gene
N/A
Organism
Gasterosteus aculeatus (Three-spined stickleback)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Arginine-glutamic acid dipeptide (RE) repeats bImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiGasterosteus aculeatus (Three-spined stickleback)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri69293 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataEupercariaPerciformesCottioideiGasterostealesGasterosteidaeGasterosteus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000007635 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

NucleusARBA annotation

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Keywords - PTMi

AcetylationARBA annotation, PhosphoproteinARBA annotation

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
69293.ENSGACP00000001963

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini13 – 111ELM2InterPro annotationAdd BLAST99
Domaini115 – 167SANTInterPro annotationAdd BLAST53

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 38DisorderedSequence analysisAdd BLAST38
Regioni170 – 237DisorderedSequence analysisAdd BLAST68
Regioni278 – 645DisorderedSequence analysisAdd BLAST368
Regioni657 – 708DisorderedSequence analysisAdd BLAST52
Regioni727 – 751DisorderedSequence analysisAdd BLAST25
Regioni1151 – 1176DisorderedSequence analysisAdd BLAST26

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 17PolarSequence analysisAdd BLAST17
Compositional biasi186 – 208PolarSequence analysisAdd BLAST23
Compositional biasi303 – 337PolarSequence analysisAdd BLAST35
Compositional biasi338 – 423PolyampholyteSequence analysisAdd BLAST86
Compositional biasi424 – 452PolarSequence analysisAdd BLAST29
Compositional biasi527 – 557PolarSequence analysisAdd BLAST31
Compositional biasi581 – 595Pro-richSequence analysisAdd BLAST15
Compositional biasi609 – 645Pro-richSequence analysisAdd BLAST37
Compositional biasi664 – 693PolarSequence analysisAdd BLAST30

Keywords - Domaini

Zinc-fingerARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2133, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153615

Identification of Orthologs from Complete Genome Data

More...
OMAi
QRMAMEQ

TreeFam database of animal gene trees

More...
TreeFami
TF328554

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00202, ZnF_GATA, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.50.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002951, Atrophin-like
IPR000949, ELM2_dom
IPR009057, Homeobox-like_sf
IPR001005, SANT/Myb
IPR017884, SANT_dom
IPR000679, Znf_GATA
IPR013088, Znf_NHR/GATA

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03154, Atrophin-1, 1 hit
PF01448, ELM2, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01189, ELM2, 1 hit
SM00717, SANT, 1 hit
SM00401, ZnF_GATA, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46689, SSF46689, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51156, ELM2, 1 hit
PS51293, SANT, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

G3N9H3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
PSHRCRSLNS TQGEIRVGPS HQAKLPEMQP RSAPSLQTQT QSEELMWTPG
60 70 80 90 100
VNDSFLLLRS MAAFAGMCDG GSTEDGCLAA SRDDTTLNAL NMLHASHYDA
110 120 130 140 150
AKALQRLVKK PLPKLIEKCW SEDDVKRFIK GLRQYGKNFF RIRKDFLPTK
160 170 180 190 200
KTGELITFYY HWKKTPEAAG TRAYRQQRRQ PSSRKAKTRS AAAPVTPSRN
210 220 230 240 250
YSVDASSASE DDLDSEDSEQ DVKSCSRCGT TSSKDWHQGR RDNALLCTTC
260 270 280 290 300
RTYENKHGCL PPAPKCAGAP FMFKPVKEEE EVNSKHGMRT RRSRAPLSTL
310 320 330 340 350
RSGHRRLTGS PTNEDHQSSQ PSPSVTTSNS LRSSSTDIKN ESSKKTNKKL
360 370 380 390 400
KEELTSPKTT KRARESPAQE PDEAEKAAPK RPKTRDPRSS RSDGEAEVEE
410 420 430 440 450
ESSSESRSAQ DDGSSDTKDI DQDNRSSSPS IPSPQQGNES DSDSSAQPNG
460 470 480 490 500
VQSDPGAVAA AVSADPPTPQ APPSHGRPIT PMQSTPLLIL PEPPPAPQTP
510 520 530 540 550
SASCCQLAAQ RRSGRPQLAP HSLSAPPCLP SASSQDSPLS AAFQPPPVLN
560 570 580 590 600
STHPRGQSPQ GPPRPAPFFR ESQLPQSALS GPQVKPPPTT PIPPSHKQMP
610 620 630 640 650
HQSATPFPQM PANLPPPPAL KPLNILPNQH PPGAPPPPLQ LMPQPLPMQL
660 670 680 690 700
LPTQLPVISP VPNHPGKSMT SSHPPASASH PLTSVTPSNI GPVPSLQPSF
710 720 730 740 750
PPLPLRPSSI TMAGGCQIQI KEEPLDEIEE AESSPSPPRS PSPEPTVVSV
760 770 780 790 800
ASHASQSARF IKHLDRGYNS CARTDLFFTP LSSSKLAKKR EEAVEKSRRE
810 820 830 840 850
AELCARQERE SFPSCFKRLQ SYSCLERASS SSHDSRMSDV QMTVQGHGRP
860 870 880 890 900
SFEQPPTTVA AVPPYIGPDT PALRTLSEYA RPHVMSPSNR SHPFYVSLSP
910 920 930 940 950
GDPLLAYHMP GLYSAEPSHR ERELRNMRER ELRERMKPGF EVKPPDMETL
960 970 980 990 1000
HPSANPMEHF ARHGAIGLPH IPGPPHHFAS FHPGLNQMER ERMMLAGPQL
1010 1020 1030 1040 1050
RPELSYAERL TAERLHAERM ASVATDPAVR LQMLNVTPHH HQHSHIHSHL
1060 1070 1080 1090 1100
HLHQQDPLGQ GSGPHPLVDP LATGPRLARF PFPGGPIHNQ LLSDLPHDHE
1110 1120 1130 1140 1150
MLRHPLFGGA YPRELQGPIP QMSAAHQLQA MHAQSAELQR MAMEQQWLHG
1160 1170
HHLHGGPLPS QEDYYSRLKK EGDKPS
Length:1,176
Mass (Da):129,002
Last modified:November 16, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3747B8B7DC1A957B
GO

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSGACT00000001966; ENSGACP00000001963; ENSGACG00000001510

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi69293.ENSGACP00000001963

Genome annotation databases

EnsembliENSGACT00000001966; ENSGACP00000001963; ENSGACG00000001510

Phylogenomic databases

eggNOGiKOG2133, Eukaryota
GeneTreeiENSGT00940000153615
OMAiQRMAMEQ
TreeFamiTF328554

Family and domain databases

CDDicd00202, ZnF_GATA, 1 hit
Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR002951, Atrophin-like
IPR000949, ELM2_dom
IPR009057, Homeobox-like_sf
IPR001005, SANT/Myb
IPR017884, SANT_dom
IPR000679, Znf_GATA
IPR013088, Znf_NHR/GATA
PfamiView protein in Pfam
PF03154, Atrophin-1, 1 hit
PF01448, ELM2, 1 hit
SMARTiView protein in SMART
SM01189, ELM2, 1 hit
SM00717, SANT, 1 hit
SM00401, ZnF_GATA, 1 hit
SUPFAMiSSF46689, SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS51156, ELM2, 1 hit
PS51293, SANT, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG3N9H3_GASAC
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G3N9H3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: October 7, 2020
This is version 55 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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