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Protein
Submitted name:

HRas proto-oncogene, GTPase

Gene

HRAS

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandGTP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-BTA-1169092 Activation of RAS in B cells
R-BTA-1250347 SHC1 events in ERBB4 signaling
R-BTA-1433557 Signaling by SCF-KIT
R-BTA-171007 p38MAPK events
R-BTA-179812 GRB2 events in EGFR signaling
R-BTA-180336 SHC1 events in EGFR signaling
R-BTA-186763 Downstream signal transduction
R-BTA-1963640 GRB2 events in ERBB2 signaling
R-BTA-210993 Tie2 Signaling
R-BTA-2179392 EGFR Transactivation by Gastrin
R-BTA-2424491 DAP12 signaling
R-BTA-2871796 FCERI mediated MAPK activation
R-BTA-375165 NCAM signaling for neurite out-growth
R-BTA-3928662 EPHB-mediated forward signaling
R-BTA-442982 Ras activation upon Ca2+ influx through NMDA receptor
R-BTA-5218921 VEGFR2 mediated cell proliferation
R-BTA-5621575 CD209 (DC-SIGN) signaling
R-BTA-5654688 SHC-mediated cascade:FGFR1
R-BTA-5654693 FRS-mediated FGFR1 signaling
R-BTA-5654699 SHC-mediated cascade:FGFR2
R-BTA-5654700 FRS-mediated FGFR2 signaling
R-BTA-5654704 SHC-mediated cascade:FGFR3
R-BTA-5654706 FRS-mediated FGFR3 signaling
R-BTA-5654712 FRS-mediated FGFR4 signaling
R-BTA-5654719 SHC-mediated cascade:FGFR4
R-BTA-5658442 Regulation of RAS by GAPs
R-BTA-5673000 RAF activation
R-BTA-5673001 RAF/MAP kinase cascade
R-BTA-5674135 MAP2K and MAPK activation
R-BTA-5675221 Negative regulation of MAPK pathway
R-BTA-8849471 PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
R-BTA-8851805 MET activates RAS signaling

Names & Taxonomyi

Protein namesi
Submitted name:
HRas proto-oncogene, GTPaseImported
Gene namesi
Name:HRASImported
OrganismiBos taurus (Bovine)Imported
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 29

Organism-specific databases

VGNCiVGNC:29951 HRAS

Subcellular locationi

Expressioni

Gene expression databases

BgeeiENSBTAG00000046644
ExpressionAtlasiG3MXH2 baseline

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0395 Eukaryota
COG1100 LUCA
GeneTreeiENSGT00860000133672
KOiK02833

Family and domain databases

InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR001806 Small_GTPase
IPR020849 Small_GTPase_Ras-type
PANTHERiPTHR24070 PTHR24070, 1 hit
PfamiView protein in Pfam
PF00071 Ras, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS51421 RAS, 1 hit

Sequencei

Sequence statusi: Complete.

G3MXH2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET
60 70 80 90 100
CLLDILDTAG QEEYSAMRDQ YMRTGEGFLC VFAINHVKSF EDIHQYREQI
110 120 130 140 150
KRVKDSDDVP MVLVGNKCDL AARTVESRQA QDLARSYGIP YIETSAKTRQ
160 170 180
GVEDAFYTLV REIRQHKVRK LSPPDEGGPG CLSCRCLLS
Length:189
Mass (Da):21,272
Last modified:November 16, 2011 - v1
Checksum:iD3A360BFEC4C225B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02063775 Genomic DNA No translation available.
RefSeqiNP_001229275.1, NM_001242346.1
UniGeneiBt.16397

Genome annotation databases

EnsembliENSBTAT00000063375; ENSBTAP00000054239; ENSBTAG00000046644
GeneIDi100298939
KEGGibta:100298939

Similar proteinsi

Entry informationi

Entry nameiG3MXH2_BOVIN
AccessioniPrimary (citable) accession number: G3MXH2
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: May 23, 2018
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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