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Protein

DNA polymerase alpha subunit B

Gene

I79_023790

Organism
Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

May play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processDNA replicationUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
DNA polymerase alpha subunit BUniRule annotation
Gene namesi
ORF Names:I79_023790Imported
OrganismiCricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)Imported
Taxonomic identifieri10029 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaCricetidaeCricetinaeCricetulus
Proteomesi
  • UP000001075 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusUniRule annotation

PTM / Processingi

Proteomic databases

PRIDEiG3IIW2

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini23 – 239Pol_alpha_B_NInterPro annotationAdd BLAST217
Domaini342 – 549DNA_pol_E_BInterPro annotationAdd BLAST208

Sequence similaritiesi

Belongs to the DNA polymerase alpha subunit B family.UniRule annotation

Phylogenomic databases

InParanoidiG3IIW2
KOiK02321

Family and domain databases

InterProiView protein in InterPro
IPR007185 DNA_pol_alpha/epsilon_bsu
IPR016722 DNA_pol_alpha_bsu
IPR013627 Pol_alpha_B_N
PANTHERiPTHR23061 PTHR23061, 1 hit
PfamiView protein in Pfam
PF04042 DNA_pol_E_B, 1 hit
PF08418 Pol_alpha_B_N, 1 hit
PIRSFiPIRSF018300 DNA_pol_alph_2, 1 hit

Sequencei

Sequence statusi: Complete.

G3IIW2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAVSTQQLAE ELQIFGLDCE DALMEKLAEL CVLYRQTEEG MVSELIAFCT
60 70 80 90 100
STGKVCLTAE ILNSFEHEVL NKKLSKAWHN ASKDSGHAGA RDIVSIQELI
110 120 130 140 150
EAEEEEETLL NSYTTPSKGP HKRSSSTPET PLTKRSVSTR SPHQLLSPSS
160 170 180 190 200
FSPSAAPSQK YSSRTNRGEV VTTFGSAQGV SWSGRGGSAS VSLKVIGYPE
210 220 230 240 250
PLTSSYKTMF QQLSDVREVL TCKIEELGSE LKEHYKIEAF TPLLEPAQEP
260 270 280 290 300
VILLGQIGCD SNGKLNSKSV ILEGDREHSS GTQIPVDLSD LKEYSLFPGQ
310 320 330 340 350
VVIMEGFNTT GRRFTATKLY EGVPLPFYQP TEEDADFEQT MVLVACGPYT
360 370 380 390 400
TSDSITYDPL LDLITIINHD RPDVCILFGP FLDAKHEQVE NCQLTSPFED
410 420 430 440 450
VFKQCLRTVI EGTRSSGSHL VFVPSLRDVQ HEPVYPQPPF TFSELPREDK
460 470 480 490 500
KRVQFVSEPC SLSINGVIFG LTSTDLLFHI GAEEICSSSG TPDRFSRILK
510 520 530 540 550
HILTQRSYYP LYPPHEDMSI DYENFYTYAQ MPVTPDVFIV PSELRYFVKD
560 570 580 590 600
ILGCVCMNPG RLTKGQVGGT YGRLYFRRQP RAMDSKGRQG LSVAAQVVRI
Length:600
Mass (Da):66,719
Last modified:November 16, 2011 - v1
Checksum:i7761573420CF42C1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JH003119 Genomic DNA Translation: EGW14747.1
RefSeqiXP_003514589.1, XM_003514541.3
XP_007608850.1, XM_007610660.2

Genome annotation databases

GeneIDi100768307
KEGGicge:100768307

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JH003119 Genomic DNA Translation: EGW14747.1
RefSeqiXP_003514589.1, XM_003514541.3
XP_007608850.1, XM_007610660.2

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiG3IIW2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi100768307
KEGGicge:100768307

Organism-specific databases

CTDi23649

Phylogenomic databases

InParanoidiG3IIW2
KOiK02321

Family and domain databases

InterProiView protein in InterPro
IPR007185 DNA_pol_alpha/epsilon_bsu
IPR016722 DNA_pol_alpha_bsu
IPR013627 Pol_alpha_B_N
PANTHERiPTHR23061 PTHR23061, 1 hit
PfamiView protein in Pfam
PF04042 DNA_pol_E_B, 1 hit
PF08418 Pol_alpha_B_N, 1 hit
PIRSFiPIRSF018300 DNA_pol_alph_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiG3IIW2_CRIGR
AccessioniPrimary (citable) accession number: G3IIW2
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: June 20, 2018
This is version 29 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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