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Protein
Submitted name:

UQCRC2 isoform 1

Gene

UQCRC2

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • metal ion binding Source: InterPro
  • metalloendopeptidase activity Source: GO_Central

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
UQCRC2 isoform 1Imported
Submitted name:
Ubiquinol-cytochrome c reductase core protein 2Imported
Submitted name:
Ubiquinol-cytochrome c reductase core protein IIImported
Submitted name:
Ubiquinol-cytochrome-c reductase complex core protein 2Imported
Gene namesi
Name:UQCRC2Imported
ORF Names:CK820_G0053876Imported
OrganismiPan troglodytes (Chimpanzee)Imported
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
Proteomesi
  • UP000002277 Componenti: Chromosome 16

Organism-specific databases

VGNCiVGNC:9404 UQCRC2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSPTRG00000007871 Expressed in 6 organ(s), highest expression level in heart

Interactioni

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000013431

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini49 – 194Peptidase_M16InterPro annotationAdd BLAST146
Domaini199 – 378Peptidase_M16_CInterPro annotationAdd BLAST180

Sequence similaritiesi

Belongs to the peptidase M16 family.UniRule annotation

Phylogenomic databases

eggNOGiKOG2583 Eukaryota
COG0612 LUCA
GeneTreeiENSGT00550000074666
KOiK00415
OMAiQFVQNNF
OrthoDBiEOG091G0A7X
TreeFamiTF105033

Family and domain databases

InterProiView protein in InterPro
IPR011249 Metalloenz_LuxS/M16
IPR011765 Pept_M16_N
IPR001431 Pept_M16_Zn_BS
IPR007863 Peptidase_M16_C
PfamiView protein in Pfam
PF00675 Peptidase_M16, 1 hit
PF05193 Peptidase_M16_C, 1 hit
SUPFAMiSSF63411 SSF63411, 2 hits
PROSITEiView protein in PROSITE
PS00143 INSULINASE, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

G2HJF6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKLLTRAGSF SRFYSLKVAP KVKATAAPAG APPQPQDLEF TKLPNGLVIA
60 70 80 90 100
SLENYSPISR IGLFIKAGSR YEDFNNLGTT HLLRLTSSLT TKGASSFKIT
110 120 130 140 150
RGIEAVGGKL SVTATRENMA YTVECLRGDV DILMEFLLNV TTAPEFRRWE
160 170 180 190 200
VADLQPQLKI DKAVAFQNPQ THVIENLHAA AYRNALANPL YCPDYRIGKV
210 220 230 240 250
TSEELHYFVQ NHFTSARMAL IGLGVSHPVL KQVAEQFLNM RGGLGLSGAK
260 270 280 290 300
ANYRGGEIRE QNGDSLVHAA FVAESAVAGS AEANAFSVLQ HVLGAGPHVK
310 320 330 340 350
RGSNTTSHLH QAVAKATQQP FDVSAFNASY SDSGLFGIYT ISQATAAGDV
360 370 380 390 400
IKAAYNQVKT IAQGNLSNTD VQAAKNKLKA GYLMSVESSE CFLEEVGSQA
410 420 430 440 450
LVAGSYVPPS TVLQQIDSVA NADIINAAKK FVSGQKSMAA SGNLGHTPFV

DEL
Length:453
Mass (Da):48,452
Last modified:November 16, 2011 - v1
Checksum:i34A3AF1666FDEBC0
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2I3TR23A0A2I3TR23_PANTR
UQCRC2 isoform 4
UQCRC2 CK820_G0053876
412Annotation score:
A0A2I3RVP0A0A2I3RVP0_PANTR
Ubiquinol-cytochrome c reductase co...
UQCRC2
437Annotation score:
A0A2J8IRB8A0A2J8IRB8_PANTR
UQCRC2 isoform 10
UQCRC2 CK820_G0053876
132Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC182429 Genomic DNA No translation available.
AK306870 mRNA Translation: BAK63864.1
GABC01010719 mRNA Translation: JAA00619.1
GABF01001605 mRNA Translation: JAA20540.1
GABD01004987 mRNA Translation: JAA28113.1
GABE01006529 mRNA Translation: JAA38210.1
NBAG03000621 Genomic DNA Translation: PNI13044.1
RefSeqiNP_001233459.1, NM_001246530.1

Genome annotation databases

EnsembliENSPTRT00000014499; ENSPTRP00000013431; ENSPTRG00000007871
GeneIDi468094
KEGGiptr:468094

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC182429 Genomic DNA No translation available.
AK306870 mRNA Translation: BAK63864.1
GABC01010719 mRNA Translation: JAA00619.1
GABF01001605 mRNA Translation: JAA20540.1
GABD01004987 mRNA Translation: JAA28113.1
GABE01006529 mRNA Translation: JAA38210.1
NBAG03000621 Genomic DNA Translation: PNI13044.1
RefSeqiNP_001233459.1, NM_001246530.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000013431

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSPTRT00000014499; ENSPTRP00000013431; ENSPTRG00000007871
GeneIDi468094
KEGGiptr:468094

Organism-specific databases

CTDi7385
VGNCiVGNC:9404 UQCRC2

Phylogenomic databases

eggNOGiKOG2583 Eukaryota
COG0612 LUCA
GeneTreeiENSGT00550000074666
KOiK00415
OMAiQFVQNNF
OrthoDBiEOG091G0A7X
TreeFamiTF105033

Gene expression databases

BgeeiENSPTRG00000007871 Expressed in 6 organ(s), highest expression level in heart

Family and domain databases

InterProiView protein in InterPro
IPR011249 Metalloenz_LuxS/M16
IPR011765 Pept_M16_N
IPR001431 Pept_M16_Zn_BS
IPR007863 Peptidase_M16_C
PfamiView protein in Pfam
PF00675 Peptidase_M16, 1 hit
PF05193 Peptidase_M16_C, 1 hit
SUPFAMiSSF63411 SSF63411, 2 hits
PROSITEiView protein in PROSITE
PS00143 INSULINASE, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiG2HJF6_PANTR
AccessioniPrimary (citable) accession number: G2HJF6
Secondary accession number(s): A0A2J8IR92
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: November 7, 2018
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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