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Entry version 68 (07 Oct 2020)
Sequence version 1 (19 Oct 2011)
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Protein

40S ribosomal protein S18

Gene
N/A
Organism
Oryctolagus cuniculus (Rabbit)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA.ARBA annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRibonucleoprotein, Ribosomal proteinUniRule annotationARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
40S ribosomal protein S18ARBA annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiOryctolagus cuniculus (Rabbit)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9986 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresLagomorphaLeporidaeOryctolagus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001811 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSOCUG00000014699, Expressed in left lung and 16 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9986.ENSOCUP00000018898

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
G1TPG3

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the universal ribosomal protein uS13 family.UniRule annotationARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3311, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000012691

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_103849_0_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
G1TPG3

KEGG Orthology (KO)

More...
KOi
K02964

Identification of Orthologs from Complete Genome Data

More...
OMAi
HKRGQKV

Database of Orthologous Groups

More...
OrthoDBi
1343043at2759

TreeFam database of animal gene trees

More...
TreeFami
TF317649

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
4.10.910.10, 1 hit

HAMAP database of protein families

More...
HAMAPi
MF_01315, Ribosomal_S13_S18, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR027437, 30s_Rbsml_prot_S13_C
IPR001892, Ribosomal_S13
IPR010979, Ribosomal_S13-like_H2TH
IPR018269, Ribosomal_S13_CS

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00416, Ribosomal_S13, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF002134, Ribosomal_S13, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46946, SSF46946, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00646, RIBOSOMAL_S13_1, 1 hit
PS50159, RIBOSOMAL_S13_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

G1TPG3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSLVIPEKFQ HILRVLNTNI DGRRKIAFAI TAIKGVGRRY AHVVLRKADI
60 70 80 90 100
DLTKRAGELT EDEVERVITI MQNPRQYKIP DWFLNRQKDV KDGKYSQVLA
110 120 130 140 150
NGLDNKLRED LERLKKIRAH RGLRHFWGLR VRGQHTKTTG RRGRTVGVSK

KK
Length:152
Mass (Da):17,719
Last modified:October 19, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4DAF0662C3F37F22
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
G1SZI5G1SZI5_RABIT
40S ribosomal protein S18
156Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A5F9CV23A0A5F9CV23_RABIT
40S ribosomal protein S18
166Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A5F9DBD5A0A5F9DBD5_RABIT
40S ribosomal protein S18
310Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AAGW02017742 Genomic DNA No translation available.

NCBI Reference Sequences

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RefSeqi
XP_002714578.1, XM_002714532.3
XP_002720764.1, XM_002720718.3
XP_017200532.1, XM_017345043.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSOCUT00000014693; ENSOCUP00000018898; ENSOCUG00000014699
ENSOCUT00000052459; ENSOCUP00000028190; ENSOCUG00000010546

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
100349921
100356144

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ocu:100349921
ocu:100356144

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAGW02017742 Genomic DNA No translation available.
RefSeqiXP_002714578.1, XM_002714532.3
XP_002720764.1, XM_002720718.3
XP_017200532.1, XM_017345043.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4D5Lelectron microscopy9.00S1-152[»]
4D61electron microscopy9.00S1-152[»]
4KZXX-ray7.81S1-152[»]
4KZYX-ray7.01S1-152[»]
4KZZX-ray7.03S1-152[»]
5K0Yelectron microscopy5.80L6-142[»]
5LZSelectron microscopy3.31SS1-152[»]
5LZTelectron microscopy3.65SS1-152[»]
5LZUelectron microscopy3.75SS1-152[»]
5LZVelectron microscopy3.35SS1-152[»]
5LZWelectron microscopy3.53SS1-152[»]
5LZXelectron microscopy3.67SS1-152[»]
5LZYelectron microscopy3.99SS1-152[»]
5LZZelectron microscopy3.47SS1-152[»]
6D90electron microscopy3.20TT1-152[»]
6D9Jelectron microscopy3.20TT1-152[»]
6GZ3electron microscopy3.60BS4-142[»]
6HCFelectron microscopy3.90T11-152[»]
6HCJelectron microscopy3.80T21-152[»]
6HCMelectron microscopy6.80T11-152[»]
6HCQelectron microscopy6.50T21-152[»]
6MTBelectron microscopy3.60SS2-145[»]
6MTCelectron microscopy3.40SS2-145[»]
6MTDelectron microscopy3.30SS2-145[»]
6MTEelectron microscopy3.40SS2-145[»]
6P4Gelectron microscopy3.10T1-152[»]
6P4Helectron microscopy3.20T1-152[»]
6P5Ielectron microscopy3.10T1-152[»]
6P5Jelectron microscopy3.10T1-152[»]
6P5Kelectron microscopy3.10T1-152[»]
6P5Nelectron microscopy3.20T1-152[»]
6R5Qelectron microscopy3.00II2-145[»]
6R6Gelectron microscopy3.70II2-145[»]
6R6Pelectron microscopy3.10II2-145[»]
6R7Qelectron microscopy3.90II2-145[»]
6SGCelectron microscopy2.80T11-152[»]
6W2Selectron microscopy3.00T1-152[»]
6W2Telectron microscopy3.36T1-152[»]
6YALelectron microscopy3.00U1-152[»]
6YAMelectron microscopy3.60U1-152[»]
6YANelectron microscopy3.48U6-147[»]
SMRiG1TPG3
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

STRINGi9986.ENSOCUP00000018898

Genome annotation databases

EnsembliENSOCUT00000014693; ENSOCUP00000018898; ENSOCUG00000014699
ENSOCUT00000052459; ENSOCUP00000028190; ENSOCUG00000010546
GeneIDi100349921
100356144
KEGGiocu:100349921
ocu:100356144

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
6222

Phylogenomic databases

eggNOGiKOG3311, Eukaryota
GeneTreeiENSGT00390000012691
HOGENOMiCLU_103849_0_1_1
InParanoidiG1TPG3
KOiK02964
OMAiHKRGQKV
OrthoDBi1343043at2759
TreeFamiTF317649

Gene expression databases

BgeeiENSOCUG00000014699, Expressed in left lung and 16 other tissues

Family and domain databases

Gene3Di4.10.910.10, 1 hit
HAMAPiMF_01315, Ribosomal_S13_S18, 1 hit
InterProiView protein in InterPro
IPR027437, 30s_Rbsml_prot_S13_C
IPR001892, Ribosomal_S13
IPR010979, Ribosomal_S13-like_H2TH
IPR018269, Ribosomal_S13_CS
PfamiView protein in Pfam
PF00416, Ribosomal_S13, 1 hit
PIRSFiPIRSF002134, Ribosomal_S13, 1 hit
SUPFAMiSSF46946, SSF46946, 1 hit
PROSITEiView protein in PROSITE
PS00646, RIBOSOMAL_S13_1, 1 hit
PS50159, RIBOSOMAL_S13_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG1TPG3_RABIT
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G1TPG3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: October 7, 2020
This is version 68 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Reference proteomeImported
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