UniProtKB - G1TGK6 (G1TGK6_RABIT)
Protein
Submitted name:
E2F transcription factor 2
Gene
E2F2
Organism
Oryctolagus cuniculus (Rabbit)
Status
Functioni
GO - Molecular functioni
- DNA binding Source: UniProtKB-KW
- DNA-binding transcription factor activity Source: InterPro
- protein dimerization activity Source: InterPro
Keywordsi
Molecular function | DNA-bindingUniRule annotationARBA annotation |
Biological process | Transcription, Transcription regulationUniRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: E2F transcription factor 2Imported |
Gene namesi | Name:E2F2Imported |
Organismi | Oryctolagus cuniculus (Rabbit)Imported |
Taxonomic identifieri | 9986 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Lagomorpha › Leporidae › Oryctolagus |
Proteomesi |
|
Subcellular locationi
Nucleus
- Nucleus UniRule annotationARBA annotation
Nucleus
- nucleus Source: UniProtKB-SubCell
Other locations
- transcription regulator complex Source: InterPro
Keywords - Cellular componenti
NucleusUniRule annotationExpressioni
Gene expression databases
Bgeei | ENSOCUG00000023896, Expressed in blood and 17 other tissues |
Interactioni
GO - Molecular functioni
- protein dimerization activity Source: InterPro
Protein-protein interaction databases
STRINGi | 9986.ENSOCUP00000016056 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 131 – 196 | E2F_TDPInterPro annotationAdd BLAST | 66 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 36 | DisorderedSequence analysisAdd BLAST | 36 | |
Regioni | 310 – 370 | DisorderedSequence analysisAdd BLAST | 61 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 209 – 229 | Sequence analysisAdd BLAST | 21 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 324 – 350 | PolarSequence analysisAdd BLAST | 27 | |
Compositional biasi | 351 – 369 | Pro-richSequence analysisAdd BLAST | 19 |
Sequence similaritiesi
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
eggNOGi | KOG2577, Eukaryota |
GeneTreei | ENSGT00940000160992 |
HOGENOMi | CLU_032091_0_0_1 |
InParanoidi | G1TGK6 |
OMAi | YLWGMDE |
OrthoDBi | 1087250at2759 |
TreeFami | TF105566 |
Family and domain databases
CDDi | cd14660, E2F_DD, 1 hit |
Gene3Di | 1.10.10.10, 1 hit |
InterProi | View protein in InterPro IPR015633, E2F IPR037241, E2F-DP_heterodim IPR032198, E2F_CC-MB IPR003316, E2F_WHTH_DNA-bd_dom IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
PANTHERi | PTHR12081, PTHR12081, 1 hit |
Pfami | View protein in Pfam PF16421, E2F_CC-MB, 1 hit PF02319, E2F_TDP, 1 hit |
SMARTi | View protein in SMART SM01372, E2F_TDP, 1 hit |
SUPFAMi | SSF144074, SSF144074, 1 hit SSF46785, SSF46785, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
G1TGK6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLSGSRVLAP AAGQPLKGAS AMSPTEPWPP GLSSPQLGPA TTTTTYYTAL
60 70 80 90 100
YPQTVPPAAA AGTCLDATPH GPEGQAVRCV PAGRLPAKRK LDLEGIGRPA
110 120 130 140 150
VPEFRTPKGK CISLEGLPSP KTPKSPGEKT RYDTSLGLLT KKFIYLLSES
160 170 180 190 200
ADGVLDLNWA AEVLAVQKRR IYDITNVLEG IQLIRKKAKN HVQWVGRGMF
210 220 230 240 250
EDPTRPGTQQ QLRQELKELT STEQALDQLI QGCSLSLKDL TEDKANQRLA
260 270 280 290 300
YVTYQDIRAV GNFKEQTVIA VKAPPQTRLE VPDKTEDNLQ IYLKSTQGPI
310 320 330 340 350
EVYLCPEEVQ EPDSPATERL PSPARSPSPD STHPSSTSPG REEPTSSSAP
360 370 380 390 400
APVPQQVPPP PPPPPLVPLE ATDSMLELPH PLLQQTEDQF LSPSLACSSP
410 420 430
LISFSPPLEQ DDYLWSLDGG EGISDLFDSY DLGDLLIN
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A5F9CKS5 | A0A5F9CKS5_RABIT | E2F transcription factor 2 | E2F2 | 440 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAGW02059828 Genomic DNA No translation available. AAGW02059829 Genomic DNA No translation available. AAGW02059830 Genomic DNA No translation available. |
RefSeqi | XP_008263913.1, XM_008265691.2 |
Genome annotation databases
Ensembli | ENSOCUT00000029930; ENSOCUP00000016056; ENSOCUG00000023896 |
GeneIDi | 100346379 |
KEGGi | ocu:100346379 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAGW02059828 Genomic DNA No translation available. AAGW02059829 Genomic DNA No translation available. AAGW02059830 Genomic DNA No translation available. |
RefSeqi | XP_008263913.1, XM_008265691.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 9986.ENSOCUP00000016056 |
Genome annotation databases
Ensembli | ENSOCUT00000029930; ENSOCUP00000016056; ENSOCUG00000023896 |
GeneIDi | 100346379 |
KEGGi | ocu:100346379 |
Organism-specific databases
CTDi | 1870 |
Phylogenomic databases
eggNOGi | KOG2577, Eukaryota |
GeneTreei | ENSGT00940000160992 |
HOGENOMi | CLU_032091_0_0_1 |
InParanoidi | G1TGK6 |
OMAi | YLWGMDE |
OrthoDBi | 1087250at2759 |
TreeFami | TF105566 |
Gene expression databases
Bgeei | ENSOCUG00000023896, Expressed in blood and 17 other tissues |
Family and domain databases
CDDi | cd14660, E2F_DD, 1 hit |
Gene3Di | 1.10.10.10, 1 hit |
InterProi | View protein in InterPro IPR015633, E2F IPR037241, E2F-DP_heterodim IPR032198, E2F_CC-MB IPR003316, E2F_WHTH_DNA-bd_dom IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
PANTHERi | PTHR12081, PTHR12081, 1 hit |
Pfami | View protein in Pfam PF16421, E2F_CC-MB, 1 hit PF02319, E2F_TDP, 1 hit |
SMARTi | View protein in SMART SM01372, E2F_TDP, 1 hit |
SUPFAMi | SSF144074, SSF144074, 1 hit SSF46785, SSF46785, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | G1TGK6_RABIT | |
Accessioni | G1TGK6Primary (citable) accession number: G1TGK6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 19, 2011 |
Last sequence update: | November 13, 2013 | |
Last modified: | December 2, 2020 | |
This is version 56 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |