UniProtKB - G1T276 (G1T276_RABIT)
Protein
Aldehyde dehydrogenase
Gene
ALDH3A2
Organism
Oryctolagus cuniculus (Rabbit)
Status
Functioni
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 207 | UniRule annotation | 1 | |
Active sitei | 241 | UniRule annotation | 1 |
GO - Molecular functioni
- oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor Source: InterPro
GO - Biological processi
- cellular aldehyde metabolic process Source: InterPro
Keywordsi
Molecular function | OxidoreductaseUniRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Aldehyde dehydrogenaseUniRule annotation |
Gene namesi | Name:ALDH3A2Imported |
Organismi | Oryctolagus cuniculus (Rabbit)Imported |
Taxonomic identifieri | 9986 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Lagomorpha › Leporidae › Oryctolagus |
Proteomesi |
|
Subcellular locationi
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 464 – 484 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | ENSOCUG00000011906, Expressed in liver and 15 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 4 – 421 | AldedhInterPro annotationAdd BLAST | 418 |
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisPhylogenomic databases
eggNOGi | KOG2456, Eukaryota |
GeneTreei | ENSGT00940000157944 |
HOGENOMi | CLU_005391_3_0_1 |
InParanoidi | G1T276 |
OMAi | RHGKRWM |
OrthoDBi | 646662at2759 |
TreeFami | TF314264 |
Family and domain databases
Gene3Di | 3.40.309.10, 1 hit 3.40.605.10, 1 hit |
InterProi | View protein in InterPro IPR016161, Ald_DH/histidinol_DH IPR016163, Ald_DH_C IPR016160, Ald_DH_CS_CYS IPR029510, Ald_DH_CS_GLU IPR016162, Ald_DH_N IPR015590, Aldehyde_DH_dom IPR012394, Aldehyde_DH_NAD(P) |
Pfami | View protein in Pfam PF00171, Aldedh, 1 hit |
PIRSFi | PIRSF036492, ALDH, 1 hit |
SUPFAMi | SSF53720, SSF53720, 1 hit |
PROSITEi | View protein in PROSITE PS00070, ALDEHYDE_DEHYDR_CYS, 1 hit PS00687, ALDEHYDE_DEHYDR_GLU, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All
G1T276-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEREVQRLRR AFRSGRSRPL RFRLQQLEAL RRMVQEREAD ILAAIAADLC
60 70 80 90 100
KSELNAYSQE VITILGEIDF MLNNLADWVT AKPVKKNLFT MLDEAYVQAE
110 120 130 140 150
PLGVVLIIGA WNYPFVLTIQ PLIGAIAAGN AVILKPSELS EHTAQVLAKL
160 170 180 190 200
LPQYLDQDLY AVVNGGVKET TELLKERFDH ILYTGNAAVG RVVMEAAAKH
210 220 230 240 250
LTPVTLELGG KSPCYIDKDC DLDTVCRRIT WGKYMNCGQT CIAPDYVLCE
260 270 280 290 300
ASLQNHIVQK IKETVQEFYG ENIKESPDYE RIINLRHFKR IQSLLEGQKI
310 320 330 340 350
AFGGETDEAT RYIAPTVLTD VDPEAKVMQE EIFGPVLPIV PVKNADEAIQ
360 370 380 390 400
FINEREKPLA LYIFSHNDKL IRRMIDETSS GGVTGNDVIM HFTLNSLPFG
410 420 430 440 450
GVGHSGMGAY HGKHTFDTFS HQRPCLLKSL KGESANKLRY PPNSQSKVDW
460 470 480
AKFFLLKQFH KGKLGLLLLA VLGIVAALLV KTGYY
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A5F9D390 | A0A5F9D390_RABIT | Aldehyde dehydrogenase | ALDH3A2 | 507 | Annotation score: | ||
A0A5F9CPG0 | A0A5F9CPG0_RABIT | Aldehyde dehydrogenase 3 family mem... | ALDH3A2 | 393 | Annotation score: | ||
A0A5F9DSF3 | A0A5F9DSF3_RABIT | Aldehyde dehydrogenase 3 family mem... | ALDH3A2 | 183 | Annotation score: |
Sequence databases
RefSeqi | XP_008248572.1, XM_008250350.2 |
Genome annotation databases
Ensembli | ENSOCUT00000011904; ENSOCUP00000010232; ENSOCUG00000011906 |
GeneIDi | 100338784 |
Similar proteinsi
Cross-referencesi
Sequence databases
RefSeqi | XP_008248572.1, XM_008250350.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 9986.ENSOCUP00000010232 |
Genome annotation databases
Ensembli | ENSOCUT00000011904; ENSOCUP00000010232; ENSOCUG00000011906 |
GeneIDi | 100338784 |
Organism-specific databases
CTDi | 224 |
Phylogenomic databases
eggNOGi | KOG2456, Eukaryota |
GeneTreei | ENSGT00940000157944 |
HOGENOMi | CLU_005391_3_0_1 |
InParanoidi | G1T276 |
OMAi | RHGKRWM |
OrthoDBi | 646662at2759 |
TreeFami | TF314264 |
Gene expression databases
Bgeei | ENSOCUG00000011906, Expressed in liver and 15 other tissues |
Family and domain databases
Gene3Di | 3.40.309.10, 1 hit 3.40.605.10, 1 hit |
InterProi | View protein in InterPro IPR016161, Ald_DH/histidinol_DH IPR016163, Ald_DH_C IPR016160, Ald_DH_CS_CYS IPR029510, Ald_DH_CS_GLU IPR016162, Ald_DH_N IPR015590, Aldehyde_DH_dom IPR012394, Aldehyde_DH_NAD(P) |
Pfami | View protein in Pfam PF00171, Aldedh, 1 hit |
PIRSFi | PIRSF036492, ALDH, 1 hit |
SUPFAMi | SSF53720, SSF53720, 1 hit |
PROSITEi | View protein in PROSITE PS00070, ALDEHYDE_DEHYDR_CYS, 1 hit PS00687, ALDEHYDE_DEHYDR_GLU, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | G1T276_RABIT | |
Accessioni | G1T276Primary (citable) accession number: G1T276 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 19, 2011 |
Last sequence update: | November 13, 2013 | |
Last modified: | August 12, 2020 | |
This is version 55 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |