Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

BRCA1 interacting protein C-terminal helicase 1

Gene

BRIP1

Organism
Oryctolagus cuniculus (Rabbit)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Catalytic activityi

ATP + H2O = ADP + phosphate.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHelicaseSAAS annotation, Hydrolase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
BRCA1 interacting protein C-terminal helicase 1Imported
Gene namesi
Name:BRIP1Imported
OrganismiOryctolagus cuniculus (Rabbit)Imported
Taxonomic identifieri9986 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresLagomorphaLeporidaeOryctolagus
Proteomesi
  • UP000001811 Componenti: Chromosome 19

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusSAAS annotation

Expressioni

Gene expression databases

BgeeiENSOCUG00000006683 Expressed in 2 organ(s), highest expression level in adult mammalian kidney

Interactioni

Protein-protein interaction databases

STRINGi9986.ENSOCUP00000005779

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 443Helicase ATP-bindingInterPro annotationAdd BLAST433

Phylogenomic databases

eggNOGiKOG1132 Eukaryota
COG1199 LUCA
GeneTreeiENSGT00530000063199
InParanoidiG1SRI0
OMAiTNNDMNQ
OrthoDBiEOG091G00LK
TreeFamiTF329449

Family and domain databases

InterProiView protein in InterPro
IPR006555 ATP-dep_Helicase_C
IPR010614 DEAD_2
IPR014013 Helic_SF1/SF2_ATP-bd_DinG/Rad3
IPR006554 Helicase-like_DEXD_c2
IPR014001 Helicase_ATP-bd
IPR027417 P-loop_NTPase
IPR013020 Rad3/Chl1-like
PfamiView protein in Pfam
PF06733 DEAD_2, 1 hit
PF13307 Helicase_C_2, 1 hit
SMARTiView protein in SMART
SM00487 DEXDc, 1 hit
SM00488 DEXDc2, 1 hit
SM00491 HELICc2, 1 hit
SUPFAMiSSF52540 SSF52540, 6 hits
TIGRFAMsiTIGR00604 rad3, 1 hit
PROSITEiView protein in PROSITE
PS51193 HELICASE_ATP_BIND_2, 1 hit

Sequencei

Sequence statusi: Complete.

G1SRI0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSVGSEYTI GGVKINFPCK AYPSQLAMMN SIVRGLNSKQ HCLLESPTGS
60 70 80 90 100
GKSLALLCSA LAWQQSLLNG KPVDEGSHKK AEEPLSCCCT CHSKTFTNND
110 120 130 140 150
MNQRTSRHFN SPSKLPSERS GASSTCQDSS EKNTLAAKLS AKKQASKSRD
160 170 180 190 200
GNDDFQVDKK RIRPLKLHSR IRKRHCFEKE EIHLNAKVVS EETVTLNSPS
210 220 230 240 250
EKINSFSPQN PPGYCSRCGC STKQGSDQES SNTIKKDQGG KSKRPKIYFG
260 270 280 290 300
TRTHKQIAQI TRELRRTAYS GVPMTILSSR DHTCVHPEVV GNFNRKEKCM
310 320 330 340 350
ELLDGKNGKS CYFYHGVHKM SDQHTLQTLQ GMCKAWEIED LVSLGKKLKA
360 370 380 390 400
CPYYTARELV EDADIIFCPY NYLLDAQIRE SMDINLKEQV VILDEAHNIE
410 420 430 440 450
DCARESASYS VTEVQLRFAR DELDSLVNNN IRKKDHEPLR AVCYSLINWL
460 470 480 490 500
EANTEHLVER DYESSCKIWS GKEMLLNLHK MGITTATFPI LQGHFSTVLQ
510 520 530 540 550
KEEKVSQIRG IEEAVEVPVI SASTQVMLKG LFMVLDYLFR QNSRFADDYK
560 570 580 590 600
IAIQQTYSWI NQTDISDKNG ILVLPKNNKR SRQKAAVHVL SFWCLNPAVA
610 620 630 640 650
FSDINGKVRT IVLTSGTLSP MKSFSSELGV TFTIQLEANH VINNSQLWVG
660 670 680 690 700
TIGSGPSGRN LCATFQHTET FEFQDEVGAL VLSVCQTVSQ GILCFLPSYK
710 720 730 740 750
LLEKLKERWL YTGLWHNLEL VKTVIVEPQG EKTDFDELLQ LYYDAIKYKG
760 770 780 790 800
GKDGALLVAV CRGKVSEGLD FSDDNARAVI TIGIPFPNVK DLQVELKREY
810 820 830 840 850
NDHHSKLRGL LPGRQWYEIQ AYRALNQALG RCIRHKNDWG ALILVDDRFG
860 870 880 890 900
NNPSRYISGL PKWVRQQIQH HSTFESALES LAEFSKKHQK EIDVTRKYVK
910 920 930 940 950
DQESTLEVAC LKDSAPAYLL DLASHLSPEN PKEDDTEMCI QELQCPKKVT
960 970 980 990 1000
ENPSLPSGII SRKRGSDPVL LEESVQTRKE KRIISRSTSP TFGKQTNRVS
1010 1020 1030 1040 1050
WSNFHSLGQF VTGKIQTTTP ELRSPKNCTS SPCTFKTENT ENKTLLPLSD
1060 1070
KPESSTPTVK TSFGSCPQSE TIVSSVKIE
Length:1,079
Mass (Da):121,324
Last modified:October 19, 2011 - v1
Checksum:iD49FC93525969EF7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAGW02039280 Genomic DNA No translation available.
AAGW02039281 Genomic DNA No translation available.
AAGW02039282 Genomic DNA No translation available.
AAGW02039283 Genomic DNA No translation available.
AAGW02039284 Genomic DNA No translation available.
AAGW02039285 Genomic DNA No translation available.
AAGW02039286 Genomic DNA No translation available.
AAGW02039287 Genomic DNA No translation available.
AAGW02039288 Genomic DNA No translation available.
AAGW02039289 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSOCUT00000006687; ENSOCUP00000005779; ENSOCUG00000006683

Similar proteinsi

Entry informationi

Entry nameiG1SRI0_RABIT
AccessioniPrimary (citable) accession number: G1SRI0
Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: September 12, 2018
This is version 38 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again