UniProtKB - G1SLA8 (G1SLA8_RABIT)
Protein
Submitted name:
GS homeobox 2
Gene
GSX2
Organism
Oryctolagus cuniculus (Rabbit)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 189 – 248 | HomeoboxPROSITE-ProRule annotationAdd BLAST | 60 |
GO - Molecular functioni
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: Ensembl
- sequence-specific double-stranded DNA binding Source: Ensembl
GO - Biological processi
- forebrain dorsal/ventral pattern formation Source: Ensembl
- forebrain morphogenesis Source: Ensembl
- hindbrain morphogenesis Source: Ensembl
- neuron fate specification Source: Ensembl
- olfactory bulb interneuron differentiation Source: Ensembl
- positive regulation of Notch signaling pathway Source: Ensembl
- positive regulation of oligodendrocyte differentiation Source: Ensembl
- regulation of cell migration Source: Ensembl
- regulation of respiratory gaseous exchange by nervous system process Source: Ensembl
- spinal cord association neuron differentiation Source: Ensembl
- subpallium neuron fate commitment Source: Ensembl
- telencephalon regionalization Source: Ensembl
Keywordsi
Molecular function | DNA-bindingPROSITE-ProRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: GS homeobox 2Imported |
Gene namesi | Name:GSX2Imported |
Organismi | Oryctolagus cuniculus (Rabbit)Imported |
Taxonomic identifieri | 9986 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Lagomorpha › Leporidae › Oryctolagus |
Proteomesi |
|
Subcellular locationi
Nucleus
- Nucleus PROSITE-ProRule annotation
Keywords - Cellular componenti
NucleusPROSITE-ProRule annotationARBA annotationExpressioni
Gene expression databases
Bgeei | ENSOCUG00000004209, Expressed in embryo and 5 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 187 – 247 | HomeoboxInterPro annotationAdd BLAST | 61 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 72 – 92 | DisorderedSequence analysisAdd BLAST | 21 | |
Regioni | 109 – 138 | DisorderedSequence analysisAdd BLAST | 30 | |
Regioni | 270 – 291 | DisorderedSequence analysisAdd BLAST | 22 |
Keywords - Domaini
HomeoboxPROSITE-ProRule annotationARBA annotationPhylogenomic databases
eggNOGi | KOG0489, Eukaryota |
GeneTreei | ENSGT00940000156043 |
HOGENOMi | CLU_077153_0_0_1 |
InParanoidi | G1SLA8 |
OMAi | PRRYHCL |
OrthoDBi | 1341872at2759 |
TreeFami | TF315938 |
Family and domain databases
CDDi | cd00086, homeodomain, 1 hit |
InterProi | View protein in InterPro IPR042191, GSH2 IPR009057, Homeobox-like_sf IPR017970, Homeobox_CS IPR001356, Homeobox_dom IPR020479, Homeobox_metazoa |
PANTHERi | PTHR47421, PTHR47421, 1 hit |
Pfami | View protein in Pfam PF00046, Homeodomain, 1 hit |
PRINTSi | PR00024, HOMEOBOX |
SMARTi | View protein in SMART SM00389, HOX, 1 hit |
SUPFAMi | SSF46689, SSF46689, 1 hit |
PROSITEi | View protein in PROSITE PS00027, HOMEOBOX_1, 1 hit PS50071, HOMEOBOX_2, 1 hit |
i Sequence
Sequence statusi: Complete.
G1SLA8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSRSFYVDSL IIKDSARPAP SLPEPHPGPD FFLPLGMQSP LVMSVPGPGC
60 70 80 90 100
PSRKSGAFCV CPLCVTSHLH SSRGPAGAGG GGGPGAGGGG AAGAAAALPL
110 120 130 140 150
LKGQFPSGPG DSQFCPRVSH GHHHHHQPQQ PGSAASAAAA AAAAAAAAAL
160 170 180 190 200
GHPQHHAPVC AATSYNVADP RRFHCLAMGG SDASQVPNGK RMRTAFTSTQ
210 220 230 240 250
LLELEREFSS NMYLSRLRRI EIATYLNLSE KQVKIWFQNR RVKHKKEGKG
260 270 280 290
TQRNSHAGCK CVSSQGLYAR SEGEDSLSPA SASEDKDISP L
Sequence databases
RefSeqi | XP_002721828.1, XM_002721782.3 |
Genome annotation databases
Ensembli | ENSOCUT00000004209; ENSOCUP00000003640; ENSOCUG00000004209 |
GeneIDi | 100340797 |
KEGGi | ocu:100340797 |
Similar proteinsi
Cross-referencesi
Sequence databases
RefSeqi | XP_002721828.1, XM_002721782.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 9986.ENSOCUP00000003640 |
Genome annotation databases
Ensembli | ENSOCUT00000004209; ENSOCUP00000003640; ENSOCUG00000004209 |
GeneIDi | 100340797 |
KEGGi | ocu:100340797 |
Organism-specific databases
CTDi | 170825 |
Phylogenomic databases
eggNOGi | KOG0489, Eukaryota |
GeneTreei | ENSGT00940000156043 |
HOGENOMi | CLU_077153_0_0_1 |
InParanoidi | G1SLA8 |
OMAi | PRRYHCL |
OrthoDBi | 1341872at2759 |
TreeFami | TF315938 |
Gene expression databases
Bgeei | ENSOCUG00000004209, Expressed in embryo and 5 other tissues |
Family and domain databases
CDDi | cd00086, homeodomain, 1 hit |
InterProi | View protein in InterPro IPR042191, GSH2 IPR009057, Homeobox-like_sf IPR017970, Homeobox_CS IPR001356, Homeobox_dom IPR020479, Homeobox_metazoa |
PANTHERi | PTHR47421, PTHR47421, 1 hit |
Pfami | View protein in Pfam PF00046, Homeodomain, 1 hit |
PRINTSi | PR00024, HOMEOBOX |
SMARTi | View protein in SMART SM00389, HOX, 1 hit |
SUPFAMi | SSF46689, SSF46689, 1 hit |
PROSITEi | View protein in PROSITE PS00027, HOMEOBOX_1, 1 hit PS50071, HOMEOBOX_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | G1SLA8_RABIT | |
Accessioni | G1SLA8Primary (citable) accession number: G1SLA8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 19, 2011 |
Last sequence update: | October 19, 2011 | |
Last modified: | December 2, 2020 | |
This is version 60 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |