Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Uncharacterized protein

Gene

PKD2

Organism
Oryctolagus cuniculus (Rabbit)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Calcium bindingi765 – 776PROSITE-ProRule annotationAdd BLAST12

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandCalciumPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:PKD2Imported
OrganismiOryctolagus cuniculus (Rabbit)Imported
Taxonomic identifieri9986 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresLagomorphaLeporidaeOryctolagus
Proteomesi
  • UP000001811 Componenti: Chromosome 15

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei226 – 244HelicalSequence analysisAdd BLAST19
Transmembranei473 – 491HelicalSequence analysisAdd BLAST19
Transmembranei511 – 528HelicalSequence analysisAdd BLAST18
Transmembranei558 – 579HelicalSequence analysisAdd BLAST22
Transmembranei599 – 621HelicalSequence analysisAdd BLAST23
Transmembranei661 – 682HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSOCUG00000002396 Expressed in 3 organ(s), highest expression level in adult mammalian kidney

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9986.ENSOCUP00000002070

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini752 – 787EF-handInterPro annotationAdd BLAST36

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili770 – 794Sequence analysisAdd BLAST25

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3599 Eukaryota
ENOG410XTGE LUCA
GeneTreeiENSGT00700000104221
InParanoidiG1SHG5
KOiK04986
OMAiGVIPSWQ
OrthoDBiEOG091G034F
TreeFamiTF316484

Family and domain databases

Gene3Di1.20.120.350, 1 hit
InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR002048 EF_hand_dom
IPR013122 PKD1_2_channel
IPR003915 PKD_2
IPR027359 Volt_channel_dom_sf
PfamiView protein in Pfam
PF08016 PKD_channel, 1 hit
PRINTSiPR01433 POLYCYSTIN2
SUPFAMiSSF47473 SSF47473, 1 hit
PROSITEiView protein in PROSITE
PS50222 EF_HAND_2, 1 hit

Sequencei

Sequence statusi: Complete.

G1SHG5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVNSSRVQPQ QPGDAKRPPA PRAQGPGRLA AGVTAAGAGL AAPGGLREQR
60 70 80 90 100
GLEIEMERIR QAAARDPPAG ASASPSPPLS SCSRQAWSRD NPGFEAEEDE
110 120 130 140 150
DEEEVEGEEG GMVVEMDVEW RPGSRRSAAS SAVSSAGARG RGLGGYHGAG
160 170 180 190 200
HPSGRRRRRE DQGPPCPSPA GGGDPLHRHL ALDGQPPRVA WAERLVRGLR
210 220 230 240 250
GLWGTRLMEE SSTNREKYLK SVLRELVTYL LFLIVLCILT YGMMSSNVYY
260 270 280 290 300
YTRIMSQLFL DTPISKSEKT NFKTLASMED FWKFTEGSLL DGLYWKIQPD
310 320 330 340 350
NATEADNRSF IFYENLLLGV PRIRQLKVRN GSCSIPQDLR DEIKECYDVY
360 370 380 390 400
SVSSEDRAPF GPRNGTAWTY TSEKDLNGSS HWGMIATYSG AGYYLDLSRT
410 420 430 440 450
REETAAQLAG LKKNVWLDRG TRATFIDFSV YNANINLFCV VRLLVEFPAT
460 470 480 490 500
GGVVPSWQFQ PVKLIRYVST FDFFLAACEI IFCFFILYYV VEEILEIRIH
510 520 530 540 550
KLHYFRSFWN CLDVVIIVLS VVAIGINIHR TSNVEALLQF LEDQNTFPNF
560 570 580 590 600
EHLAYWEIQF NNIAAVVVFF VWIKLFKFIN FNRTMSQLST TMSRCAKDLF
610 620 630 640 650
GFAIMFFIIF LAYAQLAYLV FGTQVDDFST FQECIFTQFR IILGDINFAE
660 670 680 690 700
IEEANRVLGP LYFTTFVFFM FFILLNMFLA IINDTYSEVK SDLAQQKAEM
710 720 730 740 750
ELSDLIRKGY HKALVKLKLK KNTVDDISES LRQGGGKLNF DELRQDLKGK
760 770 780 790 800
GHTDAEIEAI FTKYDQDGDQ ELTEHEHQQM RDDLEKERED LDLDHSSLPR
810 820 830 840 850
PMSSRSFPRS LDDSEEDDDE DSGHSSRRRG SISSGVSYEE FQVLVRRVDR
860 870 880 890 900
MEHSIGSIVS KIDAVIVKLE IMERAKLKRR EVLGRLLDGV AEDERLGRES
910 920 930 940 950
DVHREQMERL VREELERWES DDAASQLSHG LGTPVGLNGQ PRPRTSRPSS
960 970
SQSTEGVEGG GGNGSSNVHV
Length:970
Mass (Da):109,464
Last modified:October 19, 2011 - v1
Checksum:i74EAA0D9ED4BA47C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAGW02022593 Genomic DNA No translation available.
RefSeqiXP_002717056.1, XM_002717010.3
UniGeneiOcu.1798

Genome annotation databases

EnsembliENSOCUT00000002395; ENSOCUP00000002070; ENSOCUG00000002396
GeneIDi100008872
KEGGiocu:100008872

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAGW02022593 Genomic DNA No translation available.
RefSeqiXP_002717056.1, XM_002717010.3
UniGeneiOcu.1798

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9986.ENSOCUP00000002070

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSOCUT00000002395; ENSOCUP00000002070; ENSOCUG00000002396
GeneIDi100008872
KEGGiocu:100008872

Organism-specific databases

CTDi5311

Phylogenomic databases

eggNOGiKOG3599 Eukaryota
ENOG410XTGE LUCA
GeneTreeiENSGT00700000104221
InParanoidiG1SHG5
KOiK04986
OMAiGVIPSWQ
OrthoDBiEOG091G034F
TreeFamiTF316484

Gene expression databases

BgeeiENSOCUG00000002396 Expressed in 3 organ(s), highest expression level in adult mammalian kidney

Family and domain databases

Gene3Di1.20.120.350, 1 hit
InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR002048 EF_hand_dom
IPR013122 PKD1_2_channel
IPR003915 PKD_2
IPR027359 Volt_channel_dom_sf
PfamiView protein in Pfam
PF08016 PKD_channel, 1 hit
PRINTSiPR01433 POLYCYSTIN2
SUPFAMiSSF47473 SSF47473, 1 hit
PROSITEiView protein in PROSITE
PS50222 EF_HAND_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiG1SHG5_RABIT
AccessioniPrimary (citable) accession number: G1SHG5
Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: November 7, 2018
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again