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Protein
Submitted name:

Mitochondrial brown fat uncoupling protein 1

Gene

UCP1

Organism
Oryctolagus cuniculus (Rabbit)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransportUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Mitochondrial brown fat uncoupling protein 1Imported
Gene namesi
Name:UCP1Imported
OrganismiOryctolagus cuniculus (Rabbit)Imported
Taxonomic identifieri9986 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresLagomorphaLeporidaeOryctolagus
Proteomesi
  • UP000001811 Componenti: Chromosome 15

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSOCUG00000002297 Expressed in 1 organ(s), highest expression level in liver

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati11 – 102SolcarPROSITE-ProRule annotationAdd BLAST92
Repeati111 – 201SolcarPROSITE-ProRule annotationAdd BLAST91
Repeati210 – 295SolcarPROSITE-ProRule annotationAdd BLAST86

Sequence similaritiesi

Belongs to the mitochondrial carrier (TC 2.A.29) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiKOG0753 Eukaryota
ENOG410XRV1 LUCA
GeneTreeiENSGT00760000119170
OMAiTSVPNCA
OrthoDBiEOG091G0BQ7
TreeFamiTF323211

Family and domain databases

Gene3Di1.50.40.10, 1 hit
InterProiView protein in InterPro
IPR002030 Mit_uncoupling_UCP-like
IPR040062 Mitochondrial_carrier_protein
IPR018108 Mitochondrial_sb/sol_carrier
IPR023395 Mt_carrier_dom_sf
IPR040011 UCP1
PANTHERiPTHR24089 PTHR24089, 1 hit
PTHR24089:SF372 PTHR24089:SF372, 1 hit
PfamiView protein in Pfam
PF00153 Mito_carr, 3 hits
PRINTSiPR00784 MTUNCOUPLING
SUPFAMiSSF103506 SSF103506, 1 hit
PROSITEiView protein in PROSITE
PS50920 SOLCAR, 3 hits

Sequencei

Sequence statusi: Complete.

G1SH82-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVGTTTTDVP PTMGVKIFSA GVAACLADVI TFPLDTAKVR QQIQGEFPIT
60 70 80 90 100
SGIRYKGVLG TITTLAKTEG PLKLYSGLPA GLQRQISFAS LRIGLYDTVQ
110 120 130 140 150
EFFTSGEETA PSLGSKISAG LTTGGVAVFI GQPTEVVKVR LQAQSHLHGL
160 170 180 190 200
KPRYTGTYNA YRIIATTESL TSLWKGTTPN LLRNVIINCT ELVTYDLMKG
210 220 230 240 250
GLTRNEILAD DVPCHLLSAL IAGFCTTLLS SPVDVVKTRF INSPPGQYTS
260 270 280 290 300
VPNCAMTMFT KEGPTAFFKG FVPSFLRLGS WNVIMFVCFE KLKGELMRSR

QTVDCAT
Length:307
Mass (Da):33,153
Last modified:October 19, 2011 - v1
Checksum:iEFE42B576F36FFF3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAGW02045633 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSOCUT00000002294; ENSOCUP00000001977; ENSOCUG00000002297

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAGW02045633 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSOCUT00000002294; ENSOCUP00000001977; ENSOCUG00000002297

Phylogenomic databases

eggNOGiKOG0753 Eukaryota
ENOG410XRV1 LUCA
GeneTreeiENSGT00760000119170
OMAiTSVPNCA
OrthoDBiEOG091G0BQ7
TreeFamiTF323211

Gene expression databases

BgeeiENSOCUG00000002297 Expressed in 1 organ(s), highest expression level in liver

Family and domain databases

Gene3Di1.50.40.10, 1 hit
InterProiView protein in InterPro
IPR002030 Mit_uncoupling_UCP-like
IPR040062 Mitochondrial_carrier_protein
IPR018108 Mitochondrial_sb/sol_carrier
IPR023395 Mt_carrier_dom_sf
IPR040011 UCP1
PANTHERiPTHR24089 PTHR24089, 1 hit
PTHR24089:SF372 PTHR24089:SF372, 1 hit
PfamiView protein in Pfam
PF00153 Mito_carr, 3 hits
PRINTSiPR00784 MTUNCOUPLING
SUPFAMiSSF103506 SSF103506, 1 hit
PROSITEiView protein in PROSITE
PS50920 SOLCAR, 3 hits
ProtoNetiSearch...

Entry informationi

Entry nameiG1SH82_RABIT
AccessioniPrimary (citable) accession number: G1SH82
Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: November 7, 2018
This is version 42 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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