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Entry version 40 (05 Jun 2019)
Sequence version 2 (13 Nov 2013)
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Protein
Submitted name:

Uncharacterized protein

Gene
N/A
Organism
Oryctolagus cuniculus (Rabbit)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiOryctolagus cuniculus (Rabbit)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9986 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresLagomorphaLeporidaeOryctolagus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001811 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 14

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSOCUG00000000996 Expressed in 3 organ(s), highest expression level in prefrontal cortex

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9986.ENSOCUP00000000861

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 164TOGInterPro annotationAdd BLAST164
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati100 – 138HEATPROSITE-ProRule annotationAdd BLAST39
Domaini249 – 482TOGInterPro annotationAdd BLAST234
Domaini741 – 995TOGInterPro annotationAdd BLAST255
Domaini1118 – 1354TOGInterPro annotationAdd BLAST237

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni176 – 227DisorderedSequence analysisAdd BLAST52
Regioni479 – 533DisorderedSequence analysisAdd BLAST55
Regioni584 – 618DisorderedSequence analysisAdd BLAST35
Regioni641 – 669DisorderedSequence analysisAdd BLAST29
Regioni711 – 739DisorderedSequence analysisAdd BLAST29
Regioni988 – 1038DisorderedSequence analysisAdd BLAST51
Regioni1062 – 1105DisorderedSequence analysisAdd BLAST44

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1170 – 1194Sequence analysisAdd BLAST25

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi587 – 618PolarSequence analysisAdd BLAST32
Compositional biasi641 – 658PolarSequence analysisAdd BLAST18
Compositional biasi717 – 739PolarSequence analysisAdd BLAST23
Compositional biasi1068 – 1083PolyampholyteSequence analysisAdd BLAST16

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155574

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
G1SEI1

Identification of Orthologs from Complete Genome Data

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OMAi
EESFGVW

TreeFam database of animal gene trees

More...
TreeFami
TF101155

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.10.10, 4 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR024395 CLASP_N_dom
IPR021133 HEAT_type_2
IPR034085 TOG

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12348 CLASP_N, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01349 TOG, 4 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371 SSF48371, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50077 HEAT_REPEAT, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

G1SEI1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGLEILSAFV DKLTTRFKSY VAMVIEALID RMGDAKDKVR DEAQTLILKL
60 70 80 90 100
MDEVAPPMYV WGLLASGFKH KNYRSREGVC LCLIETLNTF GTQPLVLSKL
110 120 130 140 150
VPHLCVLFGD SNSQVRDAAI LAIVEIYRHV GEKVRVDLYT RGIPSARLKM
160 170 180 190 200
IFAKFDEVQN SGGMILSACK DKSFDDEESV DGNRPSSAAS AFKVPAPKTS
210 220 230 240 250
GNPVNSARKP GSAGGPKAGG ASKEGGAGAV DEDDFIKAFT DVPSIQIYSS
260 270 280 290 300
RELEETLNKI REILSDDKHD WDQRANALKK IRSLLVAGAA QYDCFFQHLR
310 320 330 340 350
LLDGALKLSA KDLRSQVVRE ACITVAHLST VLGNKFDHGA EAIVPTLFNL
360 370 380 390 400
VPNSAKVMAT SGCAAIRFII RHTHVPRLIP LITSNCTSKS VPVRRRSFEF
410 420 430 440 450
LDLLLQEWQT HSLERHAAVL VETIKKGIHD ADAEARVEAR KTYMGLRNHF
460 470 480 490 500
PGEAETLYNS LEPSYQKSLQ TYLKSSGSVA SLPQSDRSSS SSQESLNRPF
510 520 530 540 550
SSKWSTANPS AVAGRVSAGS SKASSLPGSL QRSRSDIDVN AAAGAKAHHA
560 570 580 590 600
SGQSVRSGRL GAGALNPGSY ASLGRVRAKL SAPLTGIGNA KTDSRGRSRT
610 620 630 640 650
KMVSQSQPGS RSGSPGRVLT TTALSTVSSG VQRVLVNSAP VQKRSKIPRS
660 670 680 690 700
QGCSREASPS RLSVGPGYGI SQSSRLSSSV SAMRVLNTGS DVEEAVADAL
710 720 730 740 750
KKPARRRYES YGMHSDDDAN SDASSACSER SYSSRNGSIP TYMRQTEDVA
760 770 780 790 800
EVLNRCASSN WSERKEGLLG LQNLLKNQRT LSRVELKRLC EIFTRMFADP
810 820 830 840 850
HGKVFSMFLE TLVDFIQVHK DDLQDWLFVL LTQLLKKMGA DLLGSVQAKV
860 870 880 890 900
QKALDVTRES FPNDLQFNIL MRFTVDQTQT PSLKTVKPAL RDQLHSFWSS
910 920 930 940 950
KVKVAILKYI ETLAKQMDPG DFINSSETRL AVSRVITWTT EPKSSDVRKA
960 970 980 990 1000
AQSVLISLFE LNTPEFTMLL GALPKTFQDG ATKLLHNHLR NTGNGTQNSM
1010 1020 1030 1040 1050
GSPLTRPTPR SPANWSSPLT SPTNTSQNTL SPSAFDYDTE NMNSEDIYSS
1060 1070 1080 1090 1100
LRGVTEAIQN FSFRSQEDMN EPLKRDSKRE DGDSMCGGPG IADPRAGGDA
1110 1120 1130 1140 1150
TDSSQTALDN KASLLHSMPA HSSPRSRDYN PYNYSDSISP FNKSALKEAM
1160 1170 1180 1190 1200
FDDDADQFPD DLSLDHSDLV AELLKELSNH NERVEERKIA LYELMKLTQE
1210 1220 1230 1240 1250
ESFSVWDEHF KTILLLLLET LGDKEVVRSA EEAASVLATS ISPEQCIKVL
1260 1270 1280 1290 1300
CPIIQTADYP INLAAIKMQT KVIERVSRET LNLLLPEIMP GLIQGYDNSE
1310 1320 1330 1340 1350
SSVRKACVFC LVAVHAVIGD ELKPHLSQLT GSKMKLLNLY IKRAQTGSGG
1360
ADPTADVPGQ S
Length:1,361
Mass (Da):148,802
Last modified:November 13, 2013 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5D59005CDF9FE37A
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AAGW02047673 Genomic DNA No translation available.
AAGW02047674 Genomic DNA No translation available.
AAGW02047675 Genomic DNA No translation available.
AAGW02047676 Genomic DNA No translation available.
AAGW02047677 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSOCUT00000000997; ENSOCUP00000000861; ENSOCUG00000000996

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAGW02047673 Genomic DNA No translation available.
AAGW02047674 Genomic DNA No translation available.
AAGW02047675 Genomic DNA No translation available.
AAGW02047676 Genomic DNA No translation available.
AAGW02047677 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi9986.ENSOCUP00000000861

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSOCUT00000000997; ENSOCUP00000000861; ENSOCUG00000000996

Phylogenomic databases

GeneTreeiENSGT00940000155574
InParanoidiG1SEI1
OMAiEESFGVW
TreeFamiTF101155

Gene expression databases

BgeeiENSOCUG00000000996 Expressed in 3 organ(s), highest expression level in prefrontal cortex

Family and domain databases

Gene3Di1.25.10.10, 4 hits
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR024395 CLASP_N_dom
IPR021133 HEAT_type_2
IPR034085 TOG
PfamiView protein in Pfam
PF12348 CLASP_N, 2 hits
SMARTiView protein in SMART
SM01349 TOG, 4 hits
SUPFAMiSSF48371 SSF48371, 2 hits
PROSITEiView protein in PROSITE
PS50077 HEAT_REPEAT, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG1SEI1_RABIT
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G1SEI1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: November 13, 2013
Last modified: June 5, 2019
This is version 40 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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