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Protein
Submitted name:

Uncharacterized protein

Gene

SERPINA1

Organism
Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:SERPINA1Imported
OrganismiNomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys)Imported
Taxonomic identifieri61853 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHylobatidaeNomascus
Proteomesi
  • UP000001073 Componenti: Chromosome 22a

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_501417846225 – 418Sequence analysisAdd BLAST394

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi61853.ENSNLEP00000020982

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini59 – 415SERPINInterPro annotationAdd BLAST357

Sequence similaritiesi

Belongs to the serpin family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG2392 Eukaryota
COG4826 LUCA
GeneTreeiENSGT00760000118839
InParanoidiG1S644
KOiK03984
OrthoDBiEOG091G0ION
TreeFamiTF343201

Family and domain databases

InterProiView protein in InterPro
IPR023795 Serpin_CS
IPR023796 Serpin_dom
IPR000215 Serpin_fam
IPR036186 Serpin_sf
PANTHERiPTHR11461 PTHR11461, 1 hit
PfamiView protein in Pfam
PF00079 Serpin, 1 hit
SMARTiView protein in SMART
SM00093 SERPIN, 1 hit
SUPFAMiSSF56574 SSF56574, 1 hit
PROSITEiView protein in PROSITE
PS00284 SERPIN, 1 hit

Sequencei

Sequence statusi: Complete.

G1S644-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPSSVSWGIL LLAGLCCLVP VSLAEDPQGD AAQKTDTSHH DQDHPTFNKI
60 70 80 90 100
APKLAEFAFS LYRQLAHQSN SSNIFFSPVS IATAFAMLSL GTKADTHDEI
110 120 130 140 150
LEGLNFNVTE IPEAQVHEGF QELLRTLNQP DSQLQLNTGN GLFLNKSLKL
160 170 180 190 200
VDKFLEDVKK LYHSEAFSVN FGDTEEAKKQ INDYVEKGTQ GKIVDSVKEL
210 220 230 240 250
DRDTVFALVN YIFFKGKWER PFEVKDTKEE DFHVDQATTV KVPMMRRLGM
260 270 280 290 300
FNIHHCEKLS SWVLLMKYLG NATAIFFLPD EGKLQHLENE LTHDIITKFL
310 320 330 340 350
ENENRRSASL YLPKLSITGT YDLKTVLGQL GITKVFGNGA DLSGVTEEAP
360 370 380 390 400
LKLSKALHKA VLTIDEKGTE AAGVMFLEAI PMSIPPEVKF NKPFVFLMIE
410
QNTKSPLFMG KVVNPTQK
Length:418
Mass (Da):46,768
Last modified:February 28, 2018 - v3
Checksum:i737B9AB8324E2AED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ADFV01193660 Genomic DNA No translation available.
ADFV01193661 Genomic DNA No translation available.
RefSeqiXP_003260972.1, XM_003260924.3
XP_004091886.1, XM_004091838.2
XP_004091889.1, XM_004091841.2
XP_004091890.1, XM_004091842.2
XP_004091891.1, XM_004091843.2
XP_012353535.1, XM_012498081.1
XP_012353536.1, XM_012498082.1

Genome annotation databases

EnsembliENSNLET00000022037; ENSNLEP00000020982; ENSNLEG00000017269
GeneIDi100585221
KEGGinle:100585221

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ADFV01193660 Genomic DNA No translation available.
ADFV01193661 Genomic DNA No translation available.
RefSeqiXP_003260972.1, XM_003260924.3
XP_004091886.1, XM_004091838.2
XP_004091889.1, XM_004091841.2
XP_004091890.1, XM_004091842.2
XP_004091891.1, XM_004091843.2
XP_012353535.1, XM_012498081.1
XP_012353536.1, XM_012498082.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi61853.ENSNLEP00000020982

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSNLET00000022037; ENSNLEP00000020982; ENSNLEG00000017269
GeneIDi100585221
KEGGinle:100585221

Organism-specific databases

CTDi5265

Phylogenomic databases

eggNOGiKOG2392 Eukaryota
COG4826 LUCA
GeneTreeiENSGT00760000118839
InParanoidiG1S644
KOiK03984
OrthoDBiEOG091G0ION
TreeFamiTF343201

Family and domain databases

InterProiView protein in InterPro
IPR023795 Serpin_CS
IPR023796 Serpin_dom
IPR000215 Serpin_fam
IPR036186 Serpin_sf
PANTHERiPTHR11461 PTHR11461, 1 hit
PfamiView protein in Pfam
PF00079 Serpin, 1 hit
SMARTiView protein in SMART
SM00093 SERPIN, 1 hit
SUPFAMiSSF56574 SSF56574, 1 hit
PROSITEiView protein in PROSITE
PS00284 SERPIN, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiG1S644_NOMLE
AccessioniPrimary (citable) accession number: G1S644
Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: February 28, 2018
Last modified: November 7, 2018
This is version 51 of the entry and version 3 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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