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Protein

BMP and activin membrane-bound inhibitor homolog

Gene

BAMBI

Organism
Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Negatively regulates TGF-beta signaling.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
BMP and activin membrane-bound inhibitor homologUniRule annotation
Gene namesi
Name:BAMBIImported
OrganismiNomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys)Imported
Taxonomic identifieri61853 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHylobatidaeNomascus
Proteomesi
  • UP000001073 Componenti: Chromosome 18

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei135 – 160HelicalSequence analysisAdd BLAST26

Keywords - Cellular componenti

Membrane

Interactioni

GO - Molecular functioni

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili160 – 180Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the BAMBI family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG4110R2C LUCA
GeneTreeiENSGT00390000014168
InParanoidiG1S5A1
KOiK10162
OrthoDBiEOG091G0PAE
TreeFamiTF333466

Family and domain databases

InterProiView protein in InterPro
IPR009345 BAMBI
PANTHERiPTHR15505:SF1 PTHR15505:SF1, 1 hit
PfamiView protein in Pfam
PF06211 BAMBI, 1 hit
PIRSFiPIRSF037456 BAMBI, 1 hit

Sequencei

Sequence statusi: Complete.

G1S5A1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MELCTMAGLL TKGEIRCYCD AAHCVATGYM CKSELSACFS RLLDPQNSNS
60 70 80 90 100
PLTHGCLDSL ASTTDICQAK QSRNHSGTTM PTLECCHEDM CNYRGLHDVL
110 120 130 140 150
SPPRGEASGQ GNRYQHDGSR NLITKVQELT SSKELWFRAA VIAVPIAGGL
160 170 180 190 200
ILVLLIMLAL RMLRSENKRL QDQRQQMLSR LHYSFHGHHS KKGQVAKLDL
210 220 230 240
ECMVPVSGHE NCCLTCDKMR QADLSNDKVL SLVHWGMYSG HGKLEFV
Length:247
Mass (Da):27,456
Last modified:February 28, 2018 - v2
Checksum:i0DD3825D3DDFA6C9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ADFV01050114 Genomic DNA No translation available.
RefSeqiXP_003269451.1, XM_003269403.2

Genome annotation databases

EnsembliENSNLET00000021722; ENSNLEP00000020689; ENSNLEG00000017028
GeneIDi100606459
KEGGinle:100606459

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ADFV01050114 Genomic DNA No translation available.
RefSeqiXP_003269451.1, XM_003269403.2

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSNLET00000021722; ENSNLEP00000020689; ENSNLEG00000017028
GeneIDi100606459
KEGGinle:100606459

Organism-specific databases

CTDi25805

Phylogenomic databases

eggNOGiENOG4110R2C LUCA
GeneTreeiENSGT00390000014168
InParanoidiG1S5A1
KOiK10162
OrthoDBiEOG091G0PAE
TreeFamiTF333466

Family and domain databases

InterProiView protein in InterPro
IPR009345 BAMBI
PANTHERiPTHR15505:SF1 PTHR15505:SF1, 1 hit
PfamiView protein in Pfam
PF06211 BAMBI, 1 hit
PIRSFiPIRSF037456 BAMBI, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiG1S5A1_NOMLE
AccessioniPrimary (citable) accession number: G1S5A1
Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: February 28, 2018
Last modified: June 20, 2018
This is version 34 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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