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Protein
Submitted name:

Serine protease 8

Gene

PRSS8

Organism
Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protease, Serine proteaseUniRule annotation

Protein family/group databases

MEROPSiS01.159

Names & Taxonomyi

Protein namesi
Submitted name:
Serine protease 8Imported
Gene namesi
Name:PRSS8Imported
OrganismiNomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys)Imported
Taxonomic identifieri61853 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHylobatidaeNomascus
Proteomesi
  • UP000001073 Componenti: Chromosome 2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 29Sequence analysisAdd BLAST29
ChainiPRO_500342135930 – 343Sequence analysisAdd BLAST314

Keywords - PTMi

Disulfide bondSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi61853.ENSNLEP00000019629

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini45 – 286Peptidase S1InterPro annotationAdd BLAST242

Sequence similaritiesi

Belongs to the peptidase S1 family.SAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3627 Eukaryota
COG5640 LUCA
GeneTreeiENSGT00900000140825
InParanoidiG1S291
KOiK08664
OMAiSYASWIH
OrthoDBiEOG091G0AH5
TreeFamiTF351676

Family and domain databases

CDDicd00190 Tryp_SPc, 1 hit
InterProiView protein in InterPro
IPR009003 Peptidase_S1_PA
IPR001314 Peptidase_S1A
IPR001254 Trypsin_dom
IPR018114 TRYPSIN_HIS
IPR033116 TRYPSIN_SER
PfamiView protein in Pfam
PF00089 Trypsin, 1 hit
PRINTSiPR00722 CHYMOTRYPSIN
SMARTiView protein in SMART
SM00020 Tryp_SPc, 1 hit
SUPFAMiSSF50494 SSF50494, 1 hit
PROSITEiView protein in PROSITE
PS50240 TRYPSIN_DOM, 1 hit
PS00134 TRYPSIN_HIS, 1 hit
PS00135 TRYPSIN_SER, 1 hit

Sequencei

Sequence statusi: Complete.

G1S291-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQKGVLGPG QLGTVAILLY LGLLRSGTGA EGAEAPCGVA PQARITGGSS
60 70 80 90 100
AEPGQWPWQV SITYDGVHVC GGSLVSEQWV LSAAHCFPSE HSKEGYEVKL
110 120 130 140 150
GAHQLDSYSE DAKVSTLKNI IPHPSYLQEG SQGDIALLQL SSPVTFSRYI
160 170 180 190 200
RPICLPAANA SFPNGLHCTV TGWGHVASSV SLMTPRPLQQ LEVPLISRET
210 220 230 240 250
CNCLYNIDAK PEEPHFVQED MVCAGYVEGG KDACQGDSGG PLSCPVEGLW
260 270 280 290 300
YLTGIVSWGD ACGARNRPGV YTLASSYASW IQSQATELQP RVVPQTQESQ
310 320 330 340
PDSNLCGSRL AFSSAPAQGL LRPILFLPLG LALGLLSPWL SEH
Length:343
Mass (Da):36,382
Last modified:October 19, 2011 - v1
Checksum:i105E53BF5370E44F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ADFV01124635 Genomic DNA No translation available.
RefSeqiXP_003280506.1, XM_003280458.3

Genome annotation databases

EnsembliENSNLET00000020619; ENSNLEP00000019629; ENSNLEG00000016193
GeneIDi100592978
KEGGinle:100592978

Similar proteinsi

Entry informationi

Entry nameiG1S291_NOMLE
AccessioniPrimary (citable) accession number: G1S291
Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: June 20, 2018
This is version 46 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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