Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 49 (11 Dec 2019)
Sequence version 2 (28 Feb 2018)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

ARID domain-containing protein

Gene

ARID1A

Organism
Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processTranscription, Transcription regulationSAAS annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
ARID domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ARID1AImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiNomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri61853 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHylobatidaeNomascus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001073 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 24

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusSAAS annotation

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
61853.ENSNLEP00000011400

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini690 – 781ARIDInterPro annotationAdd BLAST92

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 493DisorderedSequence analysisAdd BLAST493
Regioni651 – 678DisorderedSequence analysisAdd BLAST28
Regioni786 – 1020DisorderedSequence analysisAdd BLAST235
Regioni1167 – 1194DisorderedSequence analysisAdd BLAST28
Regioni1279 – 1327DisorderedSequence analysisAdd BLAST49

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi43 – 59PolarSequence analysisAdd BLAST17
Compositional biasi69 – 84PolarSequence analysisAdd BLAST16
Compositional biasi91 – 154PolarSequence analysisAdd BLAST64
Compositional biasi165 – 191PolarSequence analysisAdd BLAST27
Compositional biasi206 – 314PolarSequence analysisAdd BLAST109
Compositional biasi330 – 358PolarSequence analysisAdd BLAST29
Compositional biasi374 – 389PolarSequence analysisAdd BLAST16
Compositional biasi401 – 472PolarSequence analysisAdd BLAST72
Compositional biasi800 – 830PolarSequence analysisAdd BLAST31
Compositional biasi846 – 896PolarSequence analysisAdd BLAST51
Compositional biasi979 – 1020PolarSequence analysisAdd BLAST42
Compositional biasi1180 – 1194AcidicSequence analysisAdd BLAST15

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2510 Eukaryota
ENOG410Y034 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155194

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
G1RDV1

TreeFam database of animal gene trees

More...
TreeFami
TF320364

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.150.60, 1 hit
1.25.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001606 ARID_dom
IPR036431 ARID_dom_sf
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR021906 BAF250/Osa
IPR033388 BAF250_C
IPR030094 BAF250a

The PANTHER Classification System

More...
PANTHERi
PTHR12656 PTHR12656, 2 hits
PTHR12656:SF12 PTHR12656:SF12, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01388 ARID, 1 hit
PF12031 BAF250_C, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00501 BRIGHT, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46774 SSF46774, 1 hit
SSF48371 SSF48371, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51011 ARID, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

G1RDV1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
QDEGAGKGPA DMASQSAAAV AASGGAQQRS HHAPMSPGSS GGGGQPLART
60 70 80 90 100
PQPSSPMDQM GKMRPQPYGG TNPYSQQQGP PSGPQQGHGY PGQPYGSQTP
110 120 130 140 150
QRYPMTMQGR AQSAMGGLSY TQQIPPYGQQ GPSGYGQQGQ TPYYNQQSPH
160 170 180 190 200
PQQQQPPYSQ QPPSQTPHAQ PSYQQQPQSQ PPQLQSSQPP YSQQPSQPPH
210 220 230 240 250
QQSPAPYPSQ QSTTQQHPQS QPPYSQPQAQ SPYQQQQPQQ PAPSTLSQQA
260 270 280 290 300
AYPQPQSQQS QQTAYSQQRF PPPQELSQDS FGSQASSAPS MTSSKGGQED
310 320 330 340 350
MNLSLQSRPS SLPDLSGSID DLPMGTEGAL SPGVSTSGIS SSQGEQSNPA
360 370 380 390 400
QSPFSPHTSP HLPGIRGPSP SPVGSPASVA QSRSGPLSPA AVPGNQMPPR
410 420 430 440 450
PPSGQSDSIM HPSMNQSSIA QDRGYMQRNP QMPQYSSPQP GSALSPRQPS
460 470 480 490 500
GGQIHTGMGS YQQNSMGSYG PQGGQYGPQG GYPRQPNYNA LPNANYPSAG
510 520 530 540 550
MAGGINPMGA GGQMHGQPGI PPYGTLPPGR MSHASMGNRP YGPNMANMPP
560 570 580 590 600
QVGSGMCPPP GGMNRKTQET AVAMHVTANS IQNRPPGYPN MNQGGMMGTG
610 620 630 640 650
PPYGQGINSM AGMINPQGPP YSMGGTMANN SAGMAASPEM MGLGDVKLTP
660 670 680 690 700
ATKMNNKADG TPKTESKSKK SSSSTTTNEK ITKLYELGGE PERKMWVDRY
710 720 730 740 750
LAFTEEKAMG MTNLPAVGRK PLDLYRLYVS VKEIGGLTQV NKNKKWRELA
760 770 780 790 800
TNLNVGTSSS AASSLKKQYI QCLYAFECKI ERGEDPPPDI FAAADSKKSQ
810 820 830 840 850
PKIQPPSPAG SGSMQGPQTP QSTSSSMAEG GDLKPPTPAS TPHSQIPPLP
860 870 880 890 900
GMSRSNSVGI QDAFNDGSDS TFQKRNSMTP NPGYQPSMNT SDMMGRMSYE
910 920 930 940 950
PNKDPYGSMR KAPGSDPFMS SGQGPNGGMG DPYSRAAGPG LGNVAMGPRQ
960 970 980 990 1000
HYPYGGPYDR VRTDPGIRPE GNMITGAPHR YPPQQQQQQQ QQHDSYGNQF
1010 1020 1030 1040 1050
STQGTPSGSP FPSQQTTMYQ QQQQVRRVAG NRLACWFALK KAGPPVPASH
1060 1070 1080 1090 1100
IPPMIRRDIT FPPGSVEATQ PVLKQRRRLT MKDIGTPEAW RVMMSLKSGL
1110 1120 1130 1140 1150
LAESTWALDT INILLYDDNS IMTFNLSQLP GLLELLVEYF RRCLIEIFGI
1160 1170 1180 1190 1200
LKEYEVGDPG QRTLLDPGRF SKVSSPAPME GGEEEEELLG PKLEEEEEEE
1210 1220 1230 1240 1250
VVENDEEIAF SGKDKPASEN SEEKLISKFD KLPVKIVQKN DPFVVDCSDK
1260 1270 1280 1290 1300
LGRVQEFDSG LLHWRIGGGD TTEHIQTHFE SKTELLPSRP HAPCPPAPRK
1310 1320 1330 1340 1350
HVTTAEGTPG TTDQEGPPPD GPPEKRITAT MDDMLSTRSS TLTEDGAKSS
1360 1370 1380 1390 1400
EAIKESSKFP FGISPAQSHR NIKILEDEPH SKDETPLCTL LDWQDSLAKR
1410 1420 1430 1440 1450
CVCVSNTIRS LSFVPGNDFE MSKHPGLLLI LGKLILLHHK HPERKQAPLT
1460 1470 1480 1490 1500
YEKEEEQDQG VSCNKVEWWW DCLEMLRENT LVTLANISGQ LDLSPYPESI
1510 1520 1530 1540 1550
CLPVLDGLLH WAVCPSAEAQ DPFSTLGPNA VLSPQRLVLE TLSKLSIQDN
1560 1570 1580 1590 1600
NVDLILATPP FSRLEKLYST MVRFLSDRKN PVCREMAVVL LANLAQGDSL
1610 1620 1630 1640 1650
AARAIAVQKG SIGNLLGFLE DSLAATQFQQ SQASLLHMQN PPFEPTSVDM
1660 1670 1680 1690 1700
MRRAARALLA LAKVDENHSE FTLYESRLLD ISVSPLMNSL VSQVICDVLF

LIGQS
Length:1,705
Mass (Da):183,893
Last modified:February 28, 2018 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i445B805572C3B891
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2I3HV62A0A2I3HV62_NOMLE
ARID domain-containing protein
ARID1A
1,934Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2I3GUF0A0A2I3GUF0_NOMLE
ARID domain-containing protein
ARID1A
1,077Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2I3GXB5A0A2I3GXB5_NOMLE
ARID domain-containing protein
ARID1A
1,849Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
ADFV01067331 Genomic DNA No translation available.
ADFV01067332 Genomic DNA No translation available.
ADFV01067333 Genomic DNA No translation available.
ADFV01067334 Genomic DNA No translation available.
ADFV01067335 Genomic DNA No translation available.
ADFV01067336 Genomic DNA No translation available.
ADFV01067337 Genomic DNA No translation available.
ADFV01067338 Genomic DNA No translation available.
ADFV01067339 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSNLET00000011959; ENSNLEP00000011400; ENSNLEG00000009343

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ADFV01067331 Genomic DNA No translation available.
ADFV01067332 Genomic DNA No translation available.
ADFV01067333 Genomic DNA No translation available.
ADFV01067334 Genomic DNA No translation available.
ADFV01067335 Genomic DNA No translation available.
ADFV01067336 Genomic DNA No translation available.
ADFV01067337 Genomic DNA No translation available.
ADFV01067338 Genomic DNA No translation available.
ADFV01067339 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi61853.ENSNLEP00000011400

Genome annotation databases

EnsembliENSNLET00000011959; ENSNLEP00000011400; ENSNLEG00000009343

Phylogenomic databases

eggNOGiKOG2510 Eukaryota
ENOG410Y034 LUCA
GeneTreeiENSGT00940000155194
InParanoidiG1RDV1
TreeFamiTF320364

Family and domain databases

Gene3Di1.10.150.60, 1 hit
1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR001606 ARID_dom
IPR036431 ARID_dom_sf
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR021906 BAF250/Osa
IPR033388 BAF250_C
IPR030094 BAF250a
PANTHERiPTHR12656 PTHR12656, 2 hits
PTHR12656:SF12 PTHR12656:SF12, 2 hits
PfamiView protein in Pfam
PF01388 ARID, 1 hit
PF12031 BAF250_C, 1 hit
SMARTiView protein in SMART
SM00501 BRIGHT, 1 hit
SUPFAMiSSF46774 SSF46774, 1 hit
SSF48371 SSF48371, 1 hit
PROSITEiView protein in PROSITE
PS51011 ARID, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG1RDV1_NOMLE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G1RDV1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: February 28, 2018
Last modified: December 11, 2019
This is version 49 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again