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Protein
Submitted name:

Kallikrein B1

Gene

KLK4

Organism
Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Protease, Serine proteaseUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Kallikrein B1Imported
Submitted name:
Kallikrein related peptidase 4Imported
Gene namesi
Name:KLK4Imported
Synonyms:KLNB1Imported
OrganismiNomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys)Imported
Taxonomic identifieri61853 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHylobatidaeNomascus
Proteomesi
  • UP000001073 Componenti: Chromosome 10

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26Sequence analysisAdd BLAST26
ChainiPRO_501409147727 – 254Sequence analysisAdd BLAST228

Keywords - PTMi

Disulfide bondSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi61853.ENSNLEP00000006997

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini31 – 252Peptidase S1InterPro annotationAdd BLAST222

Sequence similaritiesi

Belongs to the peptidase S1 family.SAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

GeneTreeiENSGT00920000149034
KOiK08666
OMAiNGEDCSP
OrthoDBiEOG091G0DF7

Family and domain databases

CDDicd00190 Tryp_SPc, 1 hit
InterProiView protein in InterPro
IPR009003 Peptidase_S1_PA
IPR001314 Peptidase_S1A
IPR001254 Trypsin_dom
IPR018114 TRYPSIN_HIS
IPR033116 TRYPSIN_SER
PfamiView protein in Pfam
PF00089 Trypsin, 1 hit
PRINTSiPR00722 CHYMOTRYPSIN
SMARTiView protein in SMART
SM00020 Tryp_SPc, 1 hit
SUPFAMiSSF50494 SSF50494, 1 hit
PROSITEiView protein in PROSITE
PS50240 TRYPSIN_DOM, 1 hit
PS00134 TRYPSIN_HIS, 1 hit
PS00135 TRYPSIN_SER, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

G1R1C5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MATAGNPWGR FLGYLILGVT GSLVSGSGSQ IINGEDCSPH SQPWQVALVM
60 70 80 90 100
EDELFCSGVL VHPQWVLSAA HCFQNSYTIG LGLHSLEADR EPGSQMVEAS
110 120 130 140 150
HSVQHPEYNR PLLANDLMLI KLDESVSESD TIRNISIASQ CPTAGNSCLV
160 170 180 190 200
SGWGLLANGR MPTVLQCVNV SVVSEELCSE LYDPLYHPSM FCAGGGQDQK
210 220 230 240 250
DSCNGDSGGP LICNGYLQGL VSFGKAPCGQ VGVPGVYTNL CKFTEWIEKT

VQAS
Length:254
Mass (Da):27,072
Last modified:October 19, 2011 - v1
Checksum:iEB5AD8ED5769932B
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2I3H2W5A0A2I3H2W5_NOMLE
Uncharacterized protein
KLK4
110Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ADFV01052218 Genomic DNA No translation available.
LT631570 Genomic DNA Translation: SFW93217.1
RefSeqiXP_003269865.1, XM_003269817.3

Genome annotation databases

EnsembliENSNLET00000049675; ENSNLEP00000025435; ENSNLEG00000027940
GeneIDi100586166
KEGGinle:100586166

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ADFV01052218 Genomic DNA No translation available.
LT631570 Genomic DNA Translation: SFW93217.1
RefSeqiXP_003269865.1, XM_003269817.3

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi61853.ENSNLEP00000006997

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSNLET00000049675; ENSNLEP00000025435; ENSNLEG00000027940
GeneIDi100586166
KEGGinle:100586166

Organism-specific databases

CTDi9622

Phylogenomic databases

GeneTreeiENSGT00920000149034
KOiK08666
OMAiNGEDCSP
OrthoDBiEOG091G0DF7

Family and domain databases

CDDicd00190 Tryp_SPc, 1 hit
InterProiView protein in InterPro
IPR009003 Peptidase_S1_PA
IPR001314 Peptidase_S1A
IPR001254 Trypsin_dom
IPR018114 TRYPSIN_HIS
IPR033116 TRYPSIN_SER
PfamiView protein in Pfam
PF00089 Trypsin, 1 hit
PRINTSiPR00722 CHYMOTRYPSIN
SMARTiView protein in SMART
SM00020 Tryp_SPc, 1 hit
SUPFAMiSSF50494 SSF50494, 1 hit
PROSITEiView protein in PROSITE
PS50240 TRYPSIN_DOM, 1 hit
PS00134 TRYPSIN_HIS, 1 hit
PS00135 TRYPSIN_SER, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiG1R1C5_NOMLE
AccessioniPrimary (citable) accession number: G1R1C5
Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: June 20, 2018
This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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