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Entry version 56 (26 Feb 2020)
Sequence version 2 (28 Feb 2018)
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Protein
Submitted name:

PKHD1 ciliary IPT domain containing fibrocystin/polyductin

Gene

PKHD1

Organism
Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
PKHD1 ciliary IPT domain containing fibrocystin/polyductinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PKHD1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiNomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri61853 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHylobatidaeNomascus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001073 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 22a

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei3846 – 3869HelicalSequence analysisAdd BLAST24

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 17Sequence analysisAdd BLAST17
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_501412861118 – 4061Sequence analysisAdd BLAST4044

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
61853.ENSNLEP00000004786

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini310 – 473PA14InterPro annotationAdd BLAST164
Domaini1919 – 2040G8InterPro annotationAdd BLAST122
Domaini2734 – 2860G8InterPro annotationAdd BLAST127

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni3877 – 3915DisorderedSequence analysisAdd BLAST39

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi3895 – 3915PolyampholyteSequence analysisAdd BLAST21

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IEIF Eukaryota
ENOG410XQ01 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160697

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000057_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
G1QV16

TreeFam database of animal gene trees

More...
TreeFami
TF329582

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.160.20.10, 1 hit
2.60.40.10, 6 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR039448 Beta_helix
IPR019316 G8_domain
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
IPR002909 IPT_dom
IPR037524 PA14/GLEYA
IPR006626 PbH1
IPR012334 Pectin_lyas_fold
IPR011050 Pectin_lyase_fold/virulence
IPR028839 PKHD1

The PANTHER Classification System

More...
PANTHERi
PTHR46769:SF1 PTHR46769:SF1, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13229 Beta_helix, 2 hits
PF10162 G8, 2 hits
PF01833 TIG, 7 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01225 G8, 2 hits
SM00429 IPT, 7 hits
SM00710 PbH1, 9 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF51126 SSF51126, 2 hits
SSF81296 SSF81296, 7 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51484 G8, 2 hits
PS51820 PA14, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

G1QV16-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTAWLISLMS IEVLLLAVPH LSLHIEPEEG SLGGGTWITV IFDGLELGVL
60 70 80 90 100
YPNNGSQLEI HLVNVNMVVP ALRSIPCDVF PVFLDLPVVT CRTRSVLSEA
110 120 130 140 150
HEGLYSLEAY FGGQLVSSPN PGPRDRCTFK FSKAQTPIVH QVYPPSGVPG
160 170 180 190 200
KLIHIYGWII TGRLESFDFD AEYIDSPVIL EAQGDKWVTP CSLVNKQTGS
210 220 230 240 250
CYPIQEDHGL GTLQCHVEGD YIGLSMVHKK AWLISAKQDL FLYQTHSEIL
260 270 280 290 300
SVFPETGSLG GRTDITITGD FFHSSAQVTI AGIPCDIRHV SPRKIECTTR
310 320 330 340 350
APGKDARLTT PQPGNRGLLF EVGDAVEGLE LTEATPGYRW QIVPNASSPF
360 370 380 390 400
GFWSKEGQPF RARLSGFFVA PETNNYTFWI QADSQASLHF SWSEEPRTKV
410 420 430 440 450
KVASISVGTA DWFDSWEQNG DEGTWQQKSP KLELLGGAKY YLEAEHHGIA
460 470 480 490 500
PSRGMRIGVQ IHNTWLNPDV VTTYLREKHQ IRVRAQRLPE VQVLNVSGRG
510 520 530 540 550
NFFLTWDNVS SQPIPANATA HLIQTTIEEL LAVKCKLEPL WANILLRLGF
560 570 580 590 600
EGGPEVANSD GDLTSGMEPF CGRFSLCQPR HLVLTPPAAQ KGYRLDQYTH
610 620 630 640 650
LCLAYKGHMN KILKMTVSFT VGFQNMVKNT TCDWTLKRTS PESWQFHCTD
660 670 680 690 700
LWETCVRRSG DLQPPPANSP VLVHQIDLLP LAQETGLFYL DEIIIADTNV
710 720 730 740 750
TVSQADSGTA RPGGNLVESV SVVGSPPVYS VTSWLAGCGM EPPLITARSV
760 770 780 790 800
PTEGTEEGAG LVLVTAQRRQ RTSPPLGGHF RIQLPNTVIS DVPVQISAHH
810 820 830 840 850
LHQLLQNNAN DFTSRYLNAS DFTVKEDLYT CYEHLWTLSW STQIGDLPNF
860 870 880 890 900
IRVSDENLTG VNPAAATRVV YDGGVFLGPI FGDMLATANQ HSQVVVRVND
910 920 930 940 950
VPAHCPGSCS FQYLQGSTPC VHSVWYSVDG DINLTIYITG TGFSGDSQFL
960 970 980 990 1000
QVTVNKTNCK VIFSNQTNVV CQTDLLPVGV HRILMLVRPS GLAISATGED
1010 1020 1030 1040 1050
LFLNVEPRLD MVEPSRAADI GGLWATIRGS SLEGVSLILF GSYSCAINVT
1060 1070 1080 1090 1100
TSNSSRIQCK VPPRGEDGHI VNVTVIRGDH SAVLPRAFTY VSSLNPVIVT
1110 1120 1130 1140 1150
LSRNTSNIAG GETLVIGVAS LVNYTDLDVE VHVQDALAPV HTQSAWGLEV
1160 1170 1180 1190 1200
ALPPLPAGRH RISVSINGVS IRSQGVDLHI QYLTEVFSIE PCCGSLLGGT
1210 1220 1230 1240 1250
ILSISGIGFS RDPALVWVLV GNRSCDIVNI TEASIWCETL PAPQIPYAGA
1260 1270 1280 1290 1300
PTVPAAVEVW AGNRSFAHGP SPSLVGKGFT FMYQAAATPV VTAMQGEITN
1310 1320 1330 1340 1350
SSLSLHVGGS NLSNSIILLG NLNCDVETQS FQGNTSLSGC SIPLHSLEAG
1360 1370 1380 1390 1400
IYPLQVRQKR MGFANMSAVP QQFAVMPRIM AIFPSQGSAC GGTILTVRGV
1410 1420 1430 1440 1450
LLNSRRRSVR VDLSGPFTCG ILSLEDHTIL CQVSLEGDPL PGASFSLNVT
1460 1470 1480 1490 1500
VLVNGLTSEC QGNCTLFIRE EASPVVDALS TNTSGCLTTV LIRGQRLATT
1510 1520 1530 1540 1550
GDEPMVFVDD QLPCNVTFFN ASHVVCQTRD LAAGPHYLSV FYTRNGYACS
1560 1570 1580 1590 1600
TNVSRLFYIM PQVFHYFPKN FSIHGGSLLT IEGTGLRGQN TTSVYIDQQA
1610 1620 1630 1640 1650
CLTVNIGAEL IRCIVPTGNG SVALEIEVDG LWYHIGVISY NNAFTPELIS
1660 1670 1680 1690 1700
VSQSDDLLTF AVAQISGAAN IDIFIGMSPC MGVSGNHTVL QCVVPSLPAG
1710 1720 1730 1740 1750
EYHVRGYDCI RGWASSALVF TSRVIITAVT ENFGCLGGSL VHVFGAGFSP
1760 1770 1780 1790 1800
GNVSAAVCGA PCRVLANATV SAFSCLVLPL DASLAFLCGL KHEEDSCEAA
1810 1820 1830 1840 1850
RNTYVQCDLT VAVGTEQLLE SWPYLYICEE SSQCLFVPDH WAESMFPSFS
1860 1870 1880 1890 1900
GLFISPKVER DEVLIYNSSC NITMETEAEM ECETPNQPIT VKITEIRKRW
1910 1920 1930 1940 1950
GQNTQGNFLQ FCRRWSRTHS WFPERLPQDG DNITVESGQS LLLDANTSIL
1960 1970 1980 1990 2000
NLLHIKGGKL IFMAPGPIEL RAHAILVSDG GELRIGSEDK PFQGRAQITL
2010 2020 2030 2040 2050
YGSSYSTPFF PYGVKFLAVR NGTLSLHGSL PEVIVTRLRA TAHARDAVLA
2060 2070 2080 2090 2100
LEDAVDWHPG DEVVIISGTG VEGAKPMEEI VTVETVQDTD LYLKSPLRYS
2110 2120 2130 2140 2150
HNFTENWVAG EHHIFKATVA LLSRRITIQG TLTNEREKLL VSCQEANAPE
2160 2170 2180 2190 2200
GNLQHCLYSM SEKTLGSRDM GARVIVQSFP EEPSQVQLKG VQFRVLGQAF
2210 2220 2230 2240 2250
HKRLSSLTLV GAMRESFIQG CTVRSSFSRG LSMCGTLGLK VDSNVFYNIL
2260 2270 2280 2290 2300
GHALLVGTCM EMRYISWEAI HGRKDDWSGH GNIIRNNVII RVSGAEGLSN
2310 2320 2330 2340 2350
PEMLTPSGIY ILSPTNVIEG NRVCGAGYGY FFHLMTNKTS QAPLLSFTQN
2360 2370 2380 2390 2400
IAHSCTRYGL FVYPKFQPPW DNVTGTTLFQ SFTVWESAGG AQIFRSSNLR
2410 2420 2430 2440 2450
LKNFQVYSCR DFGIDVLESD ANTSVTDSLL LGHFAHKGSL CMSSGIKTPK
2460 2470 2480 2490 2500
RWELMVSNTT FVNFDLINCV AIRTCSDCSQ GQGGFTVKTS QLKFTNSSNL
2510 2520 2530 2540 2550
VAFPFPHAAI LEDLDGSLSG KNRSHILASM ETLSASCLVN ASFGRVVHGS
2560 2570 2580 2590 2600
ACGEGVLFRR MSIGLANTPE VSYDLTMTDS RNKTTTVNYV RDTLSNPHGW
2610 2620 2630 2640 2650
MALLLDQETY SLQSENLWIN RSLQYSATFD NFAPGNYLLL VHTDLPPYPD
2660 2670 2680 2690 2700
ILLRCGSRVG LSFPFLPSPG QNQGCDWFFN SQLRQLTYLV SGEGQVQVIL
2710 2720 2730 2740 2750
RVKEGVPPTI SASTSASESA FKWSLPETWQ GVEEGWGGYN NTIPGPGDDV
2760 2770 2780 2790 2800
LILPNRTVLV DTDLPFFKGL YVMGTLDFPV DRSNVLSVAC MVVAGGELKV
2810 2820 2830 2840 2850
GTLENPLEKE QKLLILLRAS EGVFCDRMSG IHVDPGTIGV YGKVQLCSAY
2860 2870 2880 2890 2900
PKNSWTHLGA DIASGNERII VEDAVDWRPH DKIVLSSSSY EPHEAEVLTV
2910 2920 2930 2940 2950
KEVKGHHVRI YERLKHRHIG SVHVTEDGRH IRLAAEVGLL TRNIQIQPDV
2960 2970 2980 2990 3000
SCRGRLFVGS FRKSSREEFS GVLQLLNVEI QNFGSPLYSS IEFSNVSAGS
3010 3020 3030 3040 3050
WIISSTLHQS CGGGIHAAAS HGVLLNDNIV FGTAGHGIDL EGQAYTVTNN
3060 3070 3080 3090 3100
LVVLMTQPAW STIWVAGIKV NQVKDINLHG NVVAGSERLG FHIRGHKCSS
3110 3120 3130 3140 3150
CELLWSDNVA HSSLHGLHLY KESGLDNCTR ISGFLAFKNF DYGAMLHVEN
3160 3170 3180 3190 3200
SVEIENITLV DNTIGLLAVV YVFSAPQNSI KKVQIVLRNS VIVATSSSFD
3210 3220 3230 3240 3250
CIQDKVKPHS ANLTSTDRAP SNPRGGRIGI LWPVFTSEPN QWPQEPWHKV
3260 3270 3280 3290 3300
KNDHSISGIM KLQDVTFSSF VKSCYSDDLD VCILPNAENT GILHPITAER
3310 3320 3330 3340 3350
TRMLKIKDKN KFYFSPLQPR KDLGKVVCPE LDCASPRKYL FKDLDGRALG
3360 3370 3380 3390 3400
LPPPVSVFPK TEAEWTASFF NAGTFREEQK CTYRFLMQGF ICKQTDQVVL
3410 3420 3430 3440 3450
ILDSADAIWA IQKLYPVVSV TSGFVDVFSS VNANIPCSTS GSVSTFYSIL
3460 3470 3480 3490 3500
PTRQITKVCF MDQTPQVLRF FLLGNKSTSK LLLAVFYHEL QSPHVFLGES
3510 3520 3530 3540 3550
FIPPTLVQSA SLLLNESIGA NYFNIMDNLL YVVLQGEEPI EIRSGVSIHL
3560 3570 3580 3590 3600
ALTVMVSVLE KGWEIVIVER LTNFLQIGQN QIRFIHEMPG HEETLKAIAD
3610 3620 3630 3640 3650
SRAKRKRNCP TVTCASHYRR VGQRRPLMME MNSYRASPPT TVETISKVIV
3660 3670 3680 3690 3700
IEIGDSPTVR STGMISSLSS NKLQNLAHQV ITAQQTGVLE NVLNMTIGAL
3710 3720 3730 3740 3750
LVTQSKGVTG YGNTSSFKTG NLIYIRPYAL SIVVQPSDGE VGNELPVQPQ
3760 3770 3780 3790 3800
LVFLDEQNRR VESLGPPSEP WTISASLEGA SDSVLKGCTQ AETQDGYVSF
3810 3820 3830 3840 3850
YNLAVLISGS NWHFIFTVTS PPGVNFTARS KPFAVLPVTR KEKSTIILAA
3860 3870 3880 3890 3900
CLSSVASWLA LSCLVCCWLK RSKSRKTKPE EIPESQTNNQ NNHIHISSKR
3910 3920 3930 3940 3950
RESQGPKKED TAVGEDVRMK VMLGRVNQYP HQLMNGVSRR KVSRHIVQEE
3960 3970 3980 3990 4000
EAAVPAPGTS GITSHGHICA PGAPAQQVYL QETGNWKEGQ EQLLRYQVAG
4010 4020 4030 4040 4050
QDQLLLLCPD FRQERQQLPG QSQLSKQSGS LGLSQEKKAS CGATEAFCLH
4060
SVHPETIQEQ L
Length:4,061
Mass (Da):444,495
Last modified:February 28, 2018 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC931F6C4DA4480C4
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2I3FR50A0A2I3FR50_NOMLE
PKHD1 ciliary IPT domain containing...
PKHD1
4,073Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2I3GIY6A0A2I3GIY6_NOMLE
PKHD1 ciliary IPT domain containing...
PKHD1
3,395Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
ADFV01058202 Genomic DNA No translation available.
ADFV01058203 Genomic DNA No translation available.
ADFV01058204 Genomic DNA No translation available.
ADFV01058205 Genomic DNA No translation available.
ADFV01058206 Genomic DNA No translation available.
ADFV01058207 Genomic DNA No translation available.
ADFV01058208 Genomic DNA No translation available.
ADFV01058209 Genomic DNA No translation available.
ADFV01058210 Genomic DNA No translation available.
ADFV01058211 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSNLET00000005032; ENSNLEP00000004786; ENSNLEG00000003892

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ADFV01058202 Genomic DNA No translation available.
ADFV01058203 Genomic DNA No translation available.
ADFV01058204 Genomic DNA No translation available.
ADFV01058205 Genomic DNA No translation available.
ADFV01058206 Genomic DNA No translation available.
ADFV01058207 Genomic DNA No translation available.
ADFV01058208 Genomic DNA No translation available.
ADFV01058209 Genomic DNA No translation available.
ADFV01058210 Genomic DNA No translation available.
ADFV01058211 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi61853.ENSNLEP00000004786

Genome annotation databases

EnsembliENSNLET00000005032; ENSNLEP00000004786; ENSNLEG00000003892

Phylogenomic databases

eggNOGiENOG410IEIF Eukaryota
ENOG410XQ01 LUCA
GeneTreeiENSGT00940000160697
HOGENOMiCLU_000057_1_0_1
InParanoidiG1QV16
TreeFamiTF329582

Family and domain databases

Gene3Di2.160.20.10, 1 hit
2.60.40.10, 6 hits
InterProiView protein in InterPro
IPR039448 Beta_helix
IPR019316 G8_domain
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
IPR002909 IPT_dom
IPR037524 PA14/GLEYA
IPR006626 PbH1
IPR012334 Pectin_lyas_fold
IPR011050 Pectin_lyase_fold/virulence
IPR028839 PKHD1
PANTHERiPTHR46769:SF1 PTHR46769:SF1, 1 hit
PfamiView protein in Pfam
PF13229 Beta_helix, 2 hits
PF10162 G8, 2 hits
PF01833 TIG, 7 hits
SMARTiView protein in SMART
SM01225 G8, 2 hits
SM00429 IPT, 7 hits
SM00710 PbH1, 9 hits
SUPFAMiSSF51126 SSF51126, 2 hits
SSF81296 SSF81296, 7 hits
PROSITEiView protein in PROSITE
PS51484 G8, 2 hits
PS51820 PA14, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG1QV16_NOMLE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G1QV16
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: February 28, 2018
Last modified: February 26, 2020
This is version 56 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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