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Protein
Submitted name:

Nuclear receptor subfamily 3 group C member 2

Gene

NR3C2

Organism
Myotis lucifugus (Little brown bat)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi598 – 673Nuclear receptorPROSITE-ProRule annotationAdd BLAST76

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorSAAS annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear receptor subfamily 3 group C member 2Imported
Gene namesi
Name:NR3C2Imported
OrganismiMyotis lucifugus (Little brown bat)Imported
Taxonomic identifieri59463 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaChiropteraMicrochiropteraVespertilionidaeMyotis
Proteomesi
  • UP000001074 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi59463.ENSMLUP00000007404

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini598 – 673Nuclear receptorInterPro annotationAdd BLAST76
Domaini724 – 962NR LBDInterPro annotationAdd BLAST239

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.SAAS annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3575 Eukaryota
ENOG410XRZC LUCA
GeneTreeiENSGT00760000118887
InParanoidiG1PAS1
OMAiSKICLVC
OrthoDBiEOG091G0166
TreeFamiTF106510

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR035500 NHR_like_dom_sf
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00104 Hormone_recep, 1 hit
PF00105 zf-C4, 1 hit
PRINTSiPR00047 STROIDFINGER
SMARTiView protein in SMART
SM00430 HOLI, 1 hit
SM00399 ZnF_C4, 1 hit
SUPFAMiSSF48508 SSF48508, 1 hit
PROSITEiView protein in PROSITE
PS51843 NR_LBD, 1 hit
PS00031 NUCLEAR_REC_DBD_1, 1 hit
PS51030 NUCLEAR_REC_DBD_2, 1 hit

Sequencei

Sequence statusi: Complete.

G1PAS1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
METKGYHSLP EGLDMERRWG QVSQAVDHSS LGPTERTDEN NYMEIVNVSC
60 70 80 90 100
VSGAIPNNST QGSSKEKHEL LPCLQQDNNR SGILTSDIKT ELESKELSVT
110 120 130 140 150
VAESMGLYMD SIRDAEYTYD PQNQQGSLSP AKIYQNVEQL VKFYKENGHC
160 170 180 190 200
PSTAGMSRPL RSFMADSGSS VNGGVMRAIV KSPLLCHEKS SSVCSPLNMT
210 220 230 240 250
SSACSPAGLS SVSSTSASFG NFTVHSPITQ GTPLTCSPNI ETRGSRSHSP
260 270 280 290 300
AHASNVGSPL SSPLSSMKSP VSSPPSHCSV KSPVSSPNVT LRSAVSSPAN
310 320 330 340 350
INNSRCSVSS PSNTNNRSTL SSPTASTVGS ICSPVSNAFS YTASGTPLGS
360 370 380 390 400
SAARDLVSSP DTQEKGAHEV SFPKIEEAEN ATSNGVTGQL NIVQYIKPEP
410 420 430 440 450
DGVFSSSCLR GNSKMNPASP FSVPIKQEST KHSCSGTSFK GNPTVNPFPF
460 470 480 490 500
MDSSYFSFMD DKDYYSLSGI LGPPVPGFDG SCEGSGFPVG IKQEPDDGSY
510 520 530 540 550
YPEASIPSSA IVGVNSGGQS FHYRIGAQGT ISLSRAARDQ SFQHLSSFPP
560 570 580 590 600
VNTLVESWKS HSDLASRRSD GYPVLEYIPE NVSSSTLRSV STGSSRPSKI
610 620 630 640 650
CLVCGDEASG CHYGVVTCGS CKVFFKRAVE GQHNYLCAGR NDCIIDKIRR
660 670 680 690 700
KNCPACRLQK CLQAGMNLGA RKSKKLGKLK GIHEEQSQQQ QPPPPPPPPQ
710 720 730 740 750
SPEEGTTYIA PAKEPSVNTA LVPQLSTISR ALTPSPGMIL ETIEPEIVYA
760 770 780 790 800
GYDGSKPDTA EGLLSTLNRL AGKQMIQVVK WAKVIPGFKN LPLEDQITLI
810 820 830 840 850
QYSWMCLSSF ALSWRSYKHT NSQFLYFAPD LVFNEEKMHQ SAMYELCQGM
860 870 880 890 900
HQVSLQFVRL QLTFEEYTIM KVLLLLSTVP KDGLKSQAAF EEMRTNYIKE
910 920 930 940 950
LRKMVTKCPN NSGQSWQRFY QLTKLLDSMH DLVSDLLEFC FYTFRESQAL
960 970 980
KVEFPAMLVE IISDQLPKVE SGNAKPLYFH RK
Length:982
Mass (Da):106,689
Last modified:October 19, 2011 - v1
Checksum:i347AEEFFDCB974C0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAPE02001536 Genomic DNA No translation available.
AAPE02001537 Genomic DNA No translation available.
AAPE02001538 Genomic DNA No translation available.
AAPE02001539 Genomic DNA No translation available.
AAPE02001540 Genomic DNA No translation available.
RefSeqiXP_006081825.1, XM_006081763.2

Genome annotation databases

EnsembliENSMLUT00000008109; ENSMLUP00000007404; ENSMLUG00000008108
GeneIDi102439464

Similar proteinsi

Entry informationi

Entry nameiG1PAS1_MYOLU
AccessioniPrimary (citable) accession number: G1PAS1
Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: September 12, 2018
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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