UniProtKB - G1NX56 (G1NX56_MYOLU)
Protein
Submitted name:
MYB proto-oncogene, transcription factor
Gene
MYB
Organism
Myotis lucifugus (Little brown bat)
Status
Functioni
GO - Molecular functioni
- DNA-binding transcription activator activity, RNA polymerase II-specific Source: Ensembl
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: Ensembl
GO - Biological processi
- chromatin remodeling Source: Ensembl
- negative regulation of transcription by RNA polymerase II Source: Ensembl
- positive regulation of histone H3-K4 methylation Source: Ensembl
- positive regulation of histone H3-K9 methylation Source: Ensembl
- positive regulation of T-helper cell differentiation Source: Ensembl
Keywordsi
Molecular function | DNA-bindingARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: MYB proto-oncogene, transcription factorImported |
Gene namesi | Name:MYBImported |
Organismi | Myotis lucifugus (Little brown bat)Imported |
Taxonomic identifieri | 59463 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Chiroptera › Microchiroptera › Vespertilionidae › Myotis |
Proteomesi |
|
Subcellular locationi
Nucleus
- Nucleus ARBA annotation
Cytosol
- cytosol Source: Ensembl
Nucleus
- nucleoplasm Source: Ensembl
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 35 – 86 | HTH myb-typeInterPro annotationAdd BLAST | 52 | |
Domaini | 87 – 142 | HTH myb-typeInterPro annotationAdd BLAST | 56 | |
Domaini | 143 – 193 | HTH myb-typeInterPro annotationAdd BLAST | 51 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 423 – 465 | DisorderedSequence analysisAdd BLAST | 43 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 295 – 315 | Sequence analysisAdd BLAST | 21 |
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
eggNOGi | KOG0048, Eukaryota |
GeneTreei | ENSGT00940000156248 |
HOGENOMi | CLU_015440_2_2_1 |
InParanoidi | G1NX56 |
OMAi | CGKTEEH |
TreeFami | TF326257 |
Family and domain databases
CDDi | cd00167, SANT, 3 hits |
InterProi | View protein in InterPro IPR015395, C-myb_C IPR009057, Homeobox-like_sf IPR017930, Myb_dom IPR001005, SANT/Myb IPR012642, Tscrpt_reg_Wos2-domain |
Pfami | View protein in Pfam PF09316, Cmyb_C, 1 hit PF07988, LMSTEN, 1 hit PF00249, Myb_DNA-binding, 3 hits |
SMARTi | View protein in SMART SM00717, SANT, 3 hits |
SUPFAMi | SSF46689, SSF46689, 2 hits |
PROSITEi | View protein in PROSITE PS51294, HTH_MYB, 3 hits |
i Sequence
Sequence statusi: Complete.
G1NX56-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
VGRLPANSIY SSDEDDEDIE MCDHDYDGLL PKSGKRHLGK TRWTREEDEK
60 70 80 90 100
LKKLVEQNGT DDWKVIANYL PNRTDVQCQH RWQKVLNPEL IKGPWTKEED
110 120 130 140 150
QRVIELVQKY GPKRWSVIAK HLKGRIGKQC RERWHNHLNP EVKKTSWTEE
160 170 180 190 200
EDRIIYQAHK RLGNRWAEIA KLLPGRTDNA IKNHWNSTMR RKVEQEGYLQ
210 220 230 240 250
ESSKASQPAV AASFQKNSHL MGFAHAPPSA HLPPTGQPSV NNDYSYYHIS
260 270 280 290 300
EAQNVSSHVP YPVALHVNIV NVPQPAAAAI QRHYNDEDPE KEKRIKELEL
310 320 330 340 350
LLMSTENELK GQQALPTQNH TCSYPGWHST TIADHTRPHG DSAPVSCLEE
360 370 380 390 400
HHSTPSLPVD PGCLPEESAS PARCMIVHQG AILDNVKNLL EFAETLQFID
410 420 430 440 450
SDSSSWCDLS NFELFGEAEF SPSQQHAGKA LQLQQREGNV DRPAREPSKR
460 470 480 490 500
TLSEGSLGPL KPVPPARHST IPLVILRTKR RQASPLATGD PRSFIFADVS
510 520 530 540 550
SSTPNRSPVK SLSFSPSQFL NTSSNHENLD LEMPSLTATP LSGHKLTVTT
560 570 580 590 600
PFHRDQTVKA QKENTIFRTP AIKKSILESS PRTPTPFKHA LAAQEIKYGP
610 620 630 640 650
LKMLPQTPSH LVEDLQDVIK QESDESGIVT EFQGNGPLLK KIKQEVESPT
660 670 680 690 700
DKAGNFFCSN HWEGENLNTQ LFTQASPVAD MPPLIFTSEI FLCQYIKLVK
710 720 730 740 750
LSFLKMYLVP KNRSLASPLQ PCSGAWEAAS CGKMEDQVTA SGQARKYGNA
FSTRTLVM
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAPE02007447 Genomic DNA No translation available. AAPE02007448 Genomic DNA No translation available. AAPE02007449 Genomic DNA No translation available. AAPE02007450 Genomic DNA No translation available. AAPE02007451 Genomic DNA No translation available. AAPE02007452 Genomic DNA No translation available. AAPE02007453 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENSMLUT00000002130; ENSMLUP00000001942; ENSMLUG00000002125 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAPE02007447 Genomic DNA No translation available. AAPE02007448 Genomic DNA No translation available. AAPE02007449 Genomic DNA No translation available. AAPE02007450 Genomic DNA No translation available. AAPE02007451 Genomic DNA No translation available. AAPE02007452 Genomic DNA No translation available. AAPE02007453 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 59463.ENSMLUP00000001942 |
Genome annotation databases
Ensembli | ENSMLUT00000002130; ENSMLUP00000001942; ENSMLUG00000002125 |
Phylogenomic databases
eggNOGi | KOG0048, Eukaryota |
GeneTreei | ENSGT00940000156248 |
HOGENOMi | CLU_015440_2_2_1 |
InParanoidi | G1NX56 |
OMAi | CGKTEEH |
TreeFami | TF326257 |
Family and domain databases
CDDi | cd00167, SANT, 3 hits |
InterProi | View protein in InterPro IPR015395, C-myb_C IPR009057, Homeobox-like_sf IPR017930, Myb_dom IPR001005, SANT/Myb IPR012642, Tscrpt_reg_Wos2-domain |
Pfami | View protein in Pfam PF09316, Cmyb_C, 1 hit PF07988, LMSTEN, 1 hit PF00249, Myb_DNA-binding, 3 hits |
SMARTi | View protein in SMART SM00717, SANT, 3 hits |
SUPFAMi | SSF46689, SSF46689, 2 hits |
PROSITEi | View protein in PROSITE PS51294, HTH_MYB, 3 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | G1NX56_MYOLU | |
Accessioni | G1NX56Primary (citable) accession number: G1NX56 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 19, 2011 |
Last sequence update: | October 19, 2011 | |
Last modified: | October 7, 2020 | |
This is version 55 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |