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Entry version 52 (12 Aug 2020)
Sequence version 1 (19 Oct 2011)
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Protein
Submitted name:

EH domain binding protein 1

Gene

EHBP1

Organism
Meleagris gallopavo (Wild turkey)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
EH domain binding protein 1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:EHBP1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMeleagris gallopavo (Wild turkey)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9103 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaeMeleagridinaeMeleagris
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001645 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini8 – 158C2 NT-typeInterPro annotationAdd BLAST151
Domaini447 – 554Calponin-homology (CH)InterPro annotationAdd BLAST108
Domaini1068 – 1175BMERBInterPro annotationAdd BLAST108

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni263 – 445DisorderedSequence analysisAdd BLAST183
Regioni620 – 685DisorderedSequence analysisAdd BLAST66
Regioni709 – 773DisorderedSequence analysisAdd BLAST65
Regioni786 – 823DisorderedSequence analysisAdd BLAST38
Regioni852 – 874DisorderedSequence analysisAdd BLAST23
Regioni903 – 954DisorderedSequence analysisAdd BLAST52
Regioni971 – 1007DisorderedSequence analysisAdd BLAST37
Regioni1031 – 1077DisorderedSequence analysisAdd BLAST47

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili186 – 213Sequence analysisAdd BLAST28
Coiled coili1090 – 1110Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi392 – 406PolyampholyteSequence analysisAdd BLAST15
Compositional biasi410 – 433PolarSequence analysisAdd BLAST24
Compositional biasi639 – 685PolarSequence analysisAdd BLAST47
Compositional biasi709 – 734PolyampholyteSequence analysisAdd BLAST26
Compositional biasi971 – 991PolarSequence analysisAdd BLAST21
Compositional biasi992 – 1007PolyampholyteSequence analysisAdd BLAST16
Compositional biasi1039 – 1077PolyampholyteSequence analysisAdd BLAST39

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000157597

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_004178_1_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
G1N0A2

Identification of Orthologs from Complete Genome Data

More...
OMAi
GNCRIAF

TreeFam database of animal gene trees

More...
TreeFami
TF105382

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00014, CH, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.418.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR022735, bMERB_dom
IPR001715, CH-domain
IPR036872, CH_dom_sf
IPR029944, EHBP1
IPR019448, NT-C2

The PANTHER Classification System

More...
PANTHERi
PTHR23167:SF43, PTHR23167:SF43, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00307, CH, 1 hit
PF12130, DUF3585, 1 hit
PF10358, NT-C2, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00033, CH, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47576, SSF47576, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51848, BMERB, 1 hit
PS51840, C2_NT, 1 hit
PS50021, CH, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

G1N0A2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASVWKRLQR VGKHASKFQF VASYQELMVE CTKKWQPDKL VVVWTRRSRR
60 70 80 90 100
KSSKAHSWQP GIKNPYRGVV VWPVPENVEI TVTLFKDPHA EEFEDKEWTF
110 120 130 140 150
VIENESPSGR RKALATSSIN MKQYASPMPT QTDVKLKFKP LSKKVVSATL
160 170 180 190 200
QFSLSCIFLR EGKATDEDMQ SLASLMSMKQ ADIGNLDDFE EDNEEDEENR
210 220 230 240 250
VNQEEKAAKI TEIVNQLNAL SSLDEDQDDC IKQANMPSAK SASSSEELIN
260 270 280 290 300
KLNFLDKEEQ DLADSSMNPF GDPDAAELNP FGDPDVEELD SEIASSSKAE
310 320 330 340 350
EGFYVDSYNP FKDEDAPEYL NPFDEPDPDP ETFVTIRDSP PQPAKRKNVR
360 370 380 390 400
PVDMSKYLYA DTSKAEEEEL DESNPFYEPK SSPALIKVGP LQEPEKKMKR
410 420 430 440 450
RAPEPPNLLP KTETNMSENV SAIPASRELS SSPKPSPIPS PVLGRKPNAS
460 470 480 490 500
QSLLVWCKEV TKNYRGVKIT NFTTSWRNGL SFCAILHHFR PDLINIQHRT
510 520 530 540 550
LHKKQISVRF RKAYDGFASL GISRLLEPSD MVLLAIPDKL TVMTYLYQIR
560 570 580 590 600
AHFCGQELNV VQIEENSSKS TYKVGNYETD TNSSVDQEKF YAELSDLKRQ
610 620 630 640 650
PELQAPDGGL ADFASQDDSV FVNDSGVGES ESEHQTPDDH LSPSTASPSS
660 670 680 690 700
RRTRSDTDPQ KSQQSSGRTS ASEEVGKCSS TDTAQAQPVV GRKKLLKADT
710 720 730 740 750
LDLSDLAHVS DQKEDVSPTI ACEDNDKKRH QSSDNTVGFS EQKRLGHMGS
760 770 780 790 800
PESVREDPGS RGMKQSLSPT SNLGYFYKDM DLAKKTCTSP RQAESDSDSD
810 820 830 840 850
ARMTSNHADP AAKAAQQRML SRQEELKERA RVLLEQARRD AALKAGNKQL
860 870 880 890 900
TNTIIPARSK QLNDQQDEER RRQLRERARQ LIAEARSGVK MSELPSYTEM
910 920 930 940 950
AAEKLKERSK ASGDEDEDDD NIEIDTNEEV PECSVTGGGD ELTNLENDLD
960 970 980 990 1000
STEQNSKLVD LKLKKTLETQ PQVANSLSSA AQKAVTDSSE QDVKNGTEEH
1010 1020 1030 1040 1050
RAERLQKSAE RFRNPVVFSK DSTVRKTQLQ SFSQYVESRP EMKRQRSIQE
1060 1070 1080 1090 1100
DTKRGNEEKA AITETQRKPS EDEVLNKGFK DTSQYVVGEL AALENEQKQI
1110 1120 1130 1140 1150
DTRAALVEKR LRYLMDTGRN TEEEEAMMQE WFMLVNKKNA LIRRMNQLSL
1160 1170
LEKEHDLERR YELLNRELRA MLAIE
Length:1,175
Mass (Da):132,674
Last modified:October 19, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC56B5F7D27163008
GO

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMGAT00000005537; ENSMGAP00000004815; ENSMGAG00000004927

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsembliENSMGAT00000005537; ENSMGAP00000004815; ENSMGAG00000004927

Phylogenomic databases

GeneTreeiENSGT00940000157597
HOGENOMiCLU_004178_1_1_1
InParanoidiG1N0A2
OMAiGNCRIAF
TreeFamiTF105382

Family and domain databases

CDDicd00014, CH, 1 hit
Gene3Di1.10.418.10, 1 hit
InterProiView protein in InterPro
IPR022735, bMERB_dom
IPR001715, CH-domain
IPR036872, CH_dom_sf
IPR029944, EHBP1
IPR019448, NT-C2
PANTHERiPTHR23167:SF43, PTHR23167:SF43, 1 hit
PfamiView protein in Pfam
PF00307, CH, 1 hit
PF12130, DUF3585, 1 hit
PF10358, NT-C2, 1 hit
SMARTiView protein in SMART
SM00033, CH, 1 hit
SUPFAMiSSF47576, SSF47576, 1 hit
PROSITEiView protein in PROSITE
PS51848, BMERB, 1 hit
PS51840, C2_NT, 1 hit
PS50021, CH, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG1N0A2_MELGA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G1N0A2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: August 12, 2020
This is version 52 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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