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Protein

O-acyltransferase

Gene

SOAT1

Organism
Ailuropoda melanoleuca (Giant panda)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei459UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferaseUniRule annotation, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
O-acyltransferaseUniRule annotation
Gene namesi
Name:SOAT1Imported
OrganismiAiluropoda melanoleuca (Giant panda)Imported
Taxonomic identifieri9646 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaUrsidaeAiluropoda
Proteomesi
  • UP000008912 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei140 – 161HelicalSequence analysisAdd BLAST22
Transmembranei181 – 202HelicalSequence analysisAdd BLAST22
Transmembranei223 – 247HelicalSequence analysisAdd BLAST25
Transmembranei319 – 340HelicalSequence analysisAdd BLAST22
Transmembranei360 – 388HelicalSequence analysisAdd BLAST29
Transmembranei446 – 463HelicalSequence analysisAdd BLAST18
Transmembranei469 – 488HelicalSequence analysisAdd BLAST20
Transmembranei500 – 519HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Endoplasmic reticulumUniRule annotation, Membrane

Interactioni

Protein-protein interaction databases

STRINGi9646.ENSAMEP00000015448

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili6 – 26Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG0380 Eukaryota
COG5056 LUCA
GeneTreeiENSGT00530000063122
InParanoidiG1M7X8
KOiK00637
OMAiRLCIPQF
OrthoDBiEOG091G0991
TreeFamiTF105767

Family and domain databases

InterProiView protein in InterPro
IPR004299 MBOAT_fam
IPR014371 Oat_ACAT_DAG_ARE
IPR030687 Sterol_acyltranf_meta
PANTHERiPTHR10408 PTHR10408, 1 hit
PfamiView protein in Pfam
PF03062 MBOAT, 1 hit
PIRSFiPIRSF000439 Oat_ACAT_DAG_ARE, 1 hit
PIRSF500230 Sterol_acyltranf_ACAT, 1 hit

Sequencei

Sequence statusi: Complete.

G1M7X8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVGEEKTSLR NRLSKSRENS EEKEDQRSPP KESLETPSNG RINLKQLMAK
60 70 80 90 100
KIKLTAEAEE LKPFFMKEVG SHFDDFVTNL IEKSASLDNG GCAITSFSVL
110 120 130 140 150
EGENNHRAKD LRAPPEHGKI FVVRQSLLDE LFEVDHIRTI YHMFIALLIL
160 170 180 190 200
FILSTLVVDY IDEGRLVLEF HLMSYAFGKL PVAMWTWWTM FLSTLAVPYF
210 220 230 240 250
LFQRWARGYS RSSHPLVHSL FHCFLFMIFQ IAVLGLGPTY VVLAYTLPPA
260 270 280 290 300
SRCIVILEQI RFIMKAHSFV RENVPRVLNS AKEKSKTVPI PTVNQYLYFL
310 320 330 340 350
FAPTLIYRDN YPRTPTVRWG YVAMQFLQVF GCFFYVYYIF ERLCAPLFRN
360 370 380 390 400
IKQEPFSARV LVLCVFNSIL PGVLMLLLMF FAFLHCWLNA FAEMLRFGDR
410 420 430 440 450
MFYKDWWNST SYSNYYRTWN VVVHDWLYYY AYKDFLWFFT KRFKSAAMLS
460 470 480 490 500
VFAVSAVVHE YALAVILNFF YPVLFVLFMF FGMAFNFIVN DSRKRPIWNV
510 520 530 540
MVWTSLFAGN GVILCFYSQE WYARQHCPLK NPTFLDYIRP RSWTCRYVF
Length:549
Mass (Da):64,766
Last modified:October 19, 2011 - v1
Checksum:iBA15F531E0DE34E4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ACTA01121605 Genomic DNA No translation available.
ACTA01129605 Genomic DNA No translation available.
RefSeqiXP_011219256.1, XM_011220954.2

Genome annotation databases

EnsembliENSAMET00000016091; ENSAMEP00000015448; ENSAMEG00000014663
GeneIDi100464310
KEGGiaml:100464310

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ACTA01121605 Genomic DNA No translation available.
ACTA01129605 Genomic DNA No translation available.
RefSeqiXP_011219256.1, XM_011220954.2

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9646.ENSAMEP00000015448

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSAMET00000016091; ENSAMEP00000015448; ENSAMEG00000014663
GeneIDi100464310
KEGGiaml:100464310

Organism-specific databases

CTDi6646

Phylogenomic databases

eggNOGiKOG0380 Eukaryota
COG5056 LUCA
GeneTreeiENSGT00530000063122
InParanoidiG1M7X8
KOiK00637
OMAiRLCIPQF
OrthoDBiEOG091G0991
TreeFamiTF105767

Family and domain databases

InterProiView protein in InterPro
IPR004299 MBOAT_fam
IPR014371 Oat_ACAT_DAG_ARE
IPR030687 Sterol_acyltranf_meta
PANTHERiPTHR10408 PTHR10408, 1 hit
PfamiView protein in Pfam
PF03062 MBOAT, 1 hit
PIRSFiPIRSF000439 Oat_ACAT_DAG_ARE, 1 hit
PIRSF500230 Sterol_acyltranf_ACAT, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiG1M7X8_AILME
AccessioniPrimary (citable) accession number: G1M7X8
Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: November 7, 2018
This is version 41 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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