Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 34 (05 Jun 2019)
Sequence version 1 (19 Oct 2011)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein
Submitted name:

Chromatin assembly factor 1 subunit A

Gene

CHAF1A

Organism
Ailuropoda melanoleuca (Giant panda)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Chromatin assembly factor 1 subunit AImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CHAF1AImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAiluropoda melanoleuca (Giant panda)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9646 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaUrsidaeAiluropoda
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000008912 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9646.ENSAMEP00000002117

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 214CAF1-p150_NInterPro annotationAdd BLAST214
Domaini653 – 948CAF1-p150_C2InterPro annotationAdd BLAST296

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni28 – 54DisorderedSequence analysisAdd BLAST27
Regioni159 – 218DisorderedSequence analysisAdd BLAST60
Regioni236 – 420DisorderedSequence analysisAdd BLAST185
Regioni587 – 627DisorderedSequence analysisAdd BLAST41
Regioni752 – 788DisorderedSequence analysisAdd BLAST37
Regioni844 – 865DisorderedSequence analysisAdd BLAST22
Regioni920 – 950DisorderedSequence analysisAdd BLAST31

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi28 – 42PolyampholyteSequence analysisAdd BLAST15
Compositional biasi267 – 307PolarSequence analysisAdd BLAST41
Compositional biasi312 – 420PolyampholyteSequence analysisAdd BLAST109
Compositional biasi587 – 621AcidicSequence analysisAdd BLAST35
Compositional biasi756 – 783PolarSequence analysisAdd BLAST28
Compositional biasi930 – 944PolarSequence analysisAdd BLAST15

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4364 Eukaryota
ENOG4111K9K LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00440000034888

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
G1L5F6

Identification of Orthologs from Complete Genome Data

More...
OMAi
QQFTACL

TreeFam database of animal gene trees

More...
TreeFami
TF350377

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR029105 CAF1-p150_C2
IPR029091 CAF1_asu_N
IPR022043 CAF1A

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15539 CAF1-p150_C2, 1 hit
PF15557 CAF1-p150_N, 1 hit
PF12253 CAF1A, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

G1L5F6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
TAMDCKDRPA FPVKKLIQAR LPFKRLNLVP KEKSEDGLDD TRSSEGTPAQ
60 70 80 90 100
SQVPDLETAL DTLENSCHMG SDIDCSPKLV NGKGPLDNFL RSRVKTNIDQ
110 120 130 140 150
SMVIIDLTED SSDQRDGVAT HSKLDAAACP SEEAVTGVRE EAGGDRGLLE
160 170 180 190 200
ASLEDELMCP EETLSDLPCK TEKEGAGSRG AESNGDGQKG SPPSCPVLTG
210 220 230 240 250
ALRTRSEKDR DGWSEAGGIL FKGKVPVVVL QDILAAKPPQ AKSPPTTPAE
260 270 280 290 300
RGLPSESEML ESGPEEDSVL SHSSRGSSSP TSSPEGQSAS KKQHGSPRPS
310 320 330 340 350
PTSTPIRRIT KKLVKASAEK DKLRLQRDKE RLGKQLKLRA KKEEKEKLKE
360 370 380 390 400
EAKRAKEEAR KKKEEEKELK EKERREKREK DEKEKAEKQR LKEERRKERQ
410 420 430 440 450
EALEAKLEEK RKKEEEKRLR EEEKRIKAEK AEITRFFQKP KTPQAPKTLA
460 470 480 490 500
GSCGKFAPFE IKEHMVLAPR FRTAFDHDLC DQLDQLLQQQ SGEFSFLKDL
510 520 530 540 550
KGRQPLRSGP TMVSNRNTNI HNSDVVIVES GKVDGVPERR KFGRMKLLQF
560 570 580 590 600
SENHRPAYWG TWNKKTTVIH PRDPWAQDRK LLDYEVDSDE EWEEEEPGES
610 620 630 640 650
LSHSEGDDDD EVGEDEDEDD GFFVPHGYLS EDEGVTEECA DPENHKVRQK
660 670 680 690 700
LKAKEWDEFL AKGKRFRVLQ PVKIGCVWAA DRDGGADLKV LQQFTACLLD
710 720 730 740 750
TVPPEEEQTP QASKREKRDQ QILAQLLPLL HGNVNGSKVI IREFQERCRR
760 770 780 790 800
GLLSGDSGSP DSSSASPPSP SSSRPQTPTA SEDAAVPSKA RLKRIISENS
810 820 830 840 850
VYEKRPDFRM CWYVHPQVLK TFDQEHLPVP CQWSYVTMVP SATREDSGSV
860 870 880 890 900
PATGPGQGTP VSLKRKSAGS MCITQFMKKR RHDGQVGAGD LDGFQADTEE
910 920 930 940 950
EEEEDGDCVI LDISDVGEAP APCGTTSGAG GSVAMDTSES PVPASSLGPC
Length:950
Mass (Da):105,461
Last modified:October 19, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC74D49984EFF01B9
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
ACTA01081227 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSAMET00000002207; ENSAMEP00000002117; ENSAMEG00000002002

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ACTA01081227 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi9646.ENSAMEP00000002117

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSAMET00000002207; ENSAMEP00000002117; ENSAMEG00000002002

Phylogenomic databases

eggNOGiKOG4364 Eukaryota
ENOG4111K9K LUCA
GeneTreeiENSGT00440000034888
InParanoidiG1L5F6
OMAiQQFTACL
TreeFamiTF350377

Family and domain databases

InterProiView protein in InterPro
IPR029105 CAF1-p150_C2
IPR029091 CAF1_asu_N
IPR022043 CAF1A
PfamiView protein in Pfam
PF15539 CAF1-p150_C2, 1 hit
PF15557 CAF1-p150_N, 1 hit
PF12253 CAF1A, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG1L5F6_AILME
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G1L5F6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: June 5, 2019
This is version 34 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again