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Entry version 67 (07 Apr 2021)
Sequence version 2 (26 Jun 2013)
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Protein

HECT-type E3 ubiquitin transferase

Gene

HECTD1

Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.ARBA annotation EC:2.3.2.26

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.ARBA annotation
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei2539Glycyl thioester intermediatePROSITE-ProRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTransferaseARBA annotation
Biological processUbl conjugation pathwayPROSITE-ProRule annotationARBA annotation

Enzyme and pathway databases

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00143

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
HECT-type E3 ubiquitin transferaseARBA annotation (EC:2.3.2.26ARBA annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:HECTD1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAnolis carolinensis (Green anole) (American chameleon)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri28377 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiLepidosauriaSquamataBifurcataUnidentataEpisquamataToxicoferaIguaniaDactyloidaeAnolis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001646 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Keywords - PTMi

PhosphoproteinARBA annotation

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSACAG00000015118, Expressed in embryonic post-anal tail and 14 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
28377.ENSACAP00000014864

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini361 – 483ANK_REP_REGIONInterPro annotationAdd BLAST123
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati395 – 427ANKPROSITE-ProRule annotationAdd BLAST33
Repeati426 – 458ANKPROSITE-ProRule annotationAdd BLAST33
Domaini1266 – 1338MIB/HERC2InterPro annotationAdd BLAST73
Domaini2111 – 2570HECTInterPro annotationAdd BLAST460

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni247 – 270DisorderedSequence analysisAdd BLAST24
Regioni450 – 469DisorderedSequence analysisAdd BLAST20
Regioni485 – 515DisorderedSequence analysisAdd BLAST31
Regioni627 – 657DisorderedSequence analysisAdd BLAST31
Regioni707 – 748DisorderedSequence analysisAdd BLAST42
Regioni1340 – 1403DisorderedSequence analysisAdd BLAST64
Regioni1433 – 1473DisorderedSequence analysisAdd BLAST41
Regioni1495 – 1515DisorderedSequence analysisAdd BLAST21
Regioni1674 – 1716DisorderedSequence analysisAdd BLAST43
Regioni1737 – 1761DisorderedSequence analysisAdd BLAST25
Regioni2257 – 2278DisorderedSequence analysisAdd BLAST22

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1245 – 1265Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi252 – 270PolarSequence analysisAdd BLAST19
Compositional biasi489 – 512PolyampholyteSequence analysisAdd BLAST24
Compositional biasi732 – 748PolarSequence analysisAdd BLAST17
Compositional biasi1345 – 1401PolarSequence analysisAdd BLAST57
Compositional biasi1433 – 1456PolarSequence analysisAdd BLAST24
Compositional biasi1675 – 1708AcidicSequence analysisAdd BLAST34

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the UPL family. K-HECT subfamily.ARBA annotation

Keywords - Domaini

ANK repeatPROSITE-ProRule annotation, Coiled coilSequence analysis, RepeatARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4276, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156572

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000869_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
G1KQQ3

Identification of Orthologs from Complete Genome Data

More...
OMAi
AKQWYDL

Database of Orthologous Groups

More...
OrthoDBi
34110at2759

TreeFam database of animal gene trees

More...
TreeFami
TF323674

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00078, HECTc, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.10.10, 1 hit
1.25.40.20, 1 hit
2.30.30.920, 1 hit
2.60.120.260, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002110, Ankyrin_rpt
IPR020683, Ankyrin_rpt-contain_dom
IPR036770, Ankyrin_rpt-contain_sf
IPR011989, ARM-like
IPR016024, ARM-type_fold
IPR041200, FKBP3_BTHB
IPR008979, Galactose-bd-like_sf
IPR000569, HECT_dom
IPR035983, Hect_E3_ubiquitin_ligase
IPR010606, Mib_Herc2
IPR037252, Mib_Herc2_sf
IPR012919, SUN_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12796, Ank_2, 1 hit
PF18410, BTHB, 1 hit
PF00632, HECT, 1 hit
PF06701, MIB_HERC2, 1 hit
PF07738, Sad1_UNC, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00248, ANK, 3 hits
SM00119, HECTc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF159034, SSF159034, 1 hit
SSF48371, SSF48371, 1 hit
SSF48403, SSF48403, 1 hit
SSF49785, SSF49785, 1 hit
SSF56204, SSF56204, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50297, ANK_REP_REGION, 1 hit
PS50088, ANK_REPEAT, 2 hits
PS50237, HECT, 1 hit
PS51416, MIB_HERC2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

G1KQQ3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MADVDPDTLL EWLQMGQGDE RDMQLIALEQ LCMLLLMSDN VDRCFETCPP
60 70 80 90 100
RTFLPALCKI FLDESAPDNV LEVTARAITY YLDVSAERTR RIVGVDGAIK
110 120 130 140 150
ALCNRLVVVE LNNRTSRDLA EQCVKVLELI CTRESGAVFE AGGLNCVLTF
160 170 180 190 200
IRDSGHLVHK DTLHSAMAVV SRLCGKMEPQ DSSLEICVES LSSLLKHEDH
210 220 230 240 250
QVSDGALRCF ASLADRFTRR GVDPAPLAKH GLTEELLSRM AAAGGTASGP
260 270 280 290 300
SSACKPGRSS TGAPSANADS KLSNQVSTIV SLLSTLCRGS PVVTHDLLRS
310 320 330 340 350
ELPDSIESAL QGDERCVLDT MRLVDLLLVL LFEGRKALPK SSAGSTGRIP
360 370 380 390 400
GLRRLDSTGE RSHRQLIDCI RSKDTDALID AIDTGAFEVN FMDDVGQTLL
410 420 430 440 450
NWASAFGTQE MVEFLCERGA DVNRGQRSSS LHYAACFGRP QVAKTLLRHG
460 470 480 490 500
ANPDLRDEDG KTPLDKARER GHSEVVAILQ SPGDWMCPVN KGDEKKKKDA
510 520 530 540 550
NKDEEESNEP KGDPEMAPIY LKRLLPVFAQ TFQQTMLPSI RKASLALIRK
560 570 580 590 600
MIHFCSEALL KEVCDSDAGH NLPTVLVEIT ATVLDQEDDD DGHLLALQII
610 620 630 640 650
RDLVDKGGDL FLDQLARLGV ISKVSTLAGP SSDDENEEES KPEKEDEPQE
660 670 680 690 700
DAKELQQGKP YHWRDWSIIR GRDCLYIWSD AAALELSNGS NGWFRFILDG
710 720 730 740 750
KLATMYSSGS PEGGSDSSES RSEFLEKLQR ARSQVKPSTT SQPILSAPGP
760 770 780 790 800
TKLTVGNWSL TCLKEGEIAI HNSDGQQATI LKEDLPGFVF ESNRGTKHSF
810 820 830 840 850
TAETSLGSEF VTGWTGKRGR KLKSKLEKTK QKVRTMARDL YDDHFKAVES
860 870 880 890 900
MPRGVVVTLR NIATQLESAW ELHTNRQFIE GENTWRDLMK TALENLIVLL
910 920 930 940 950
KDENTISPYE MCSSGLVQAL LTVLNNNVDF DVKQDCSQLV ERINVFKTAF
960 970 980 990 1000
SENEDDESRP AIALIRKLIA VLESIERLPL HLYDTPGSTY NLQILTRRLR
1010 1020 1030 1040 1050
FRLERASGET ALIDRTSRML KMEPLATVES LEQYLLKMVA KQWYDFDRAS
1060 1070 1080 1090 1100
FVFVRKLREG QTFIFRHQHD FDENGIIYWI GTNAKTAYEW VNPAAYGLVV
1110 1120 1130 1140 1150
VTSSEGRNLP YGRLEDILSR DSSALNCHTN DDKNAWFAID LGLWVIPSAY
1160 1170 1180 1190 1200
TLRHARGYGR SALRNWVFQV SKDGQNWTTL YTHVDDCSLN EPGSTATWPL
1210 1220 1230 1240 1250
DPPKDEKQGW RHIRIKQMGK NASGQTHYLS LSGFELYGTV NGVCEDQLGK
1260 1270 1280 1290 1300
AAKEAEANLR RQRRLVRSQV LKYMVPGARV IRGIDWKWRD QDGSPQGEGT
1310 1320 1330 1340 1350
VTGELHNGWI DVTWDAGGSN SYRMGAEGKF DLKLAPGYDP DSAASPKPVS
1360 1370 1380 1390 1400
STVSGTTQSW SSLVKNNCPD KMTAAAGSSS RKGSSSSVCS VASSSDISLG
1410 1420 1430 1440 1450
STKMERRSEN LMEQNIVSGT DVHEPIVVLS SADSMPQTEV GSASSASTST
1460 1470 1480 1490 1500
LTADVGNENV ERKLGPDNSI RATGESNAIS MGIVSVSSPD VSSVSELTNK
1510 1520 1530 1540 1550
EATSQRPLSS SASNRLSVSS LLAAGAPMSS SASVPNLSSR ETSSLESFVR
1560 1570 1580 1590 1600
RVANIARTNA TNNMNLSRSS SDNNTNTLGR NVMSTATSPL MGAQSFPNLT
1610 1620 1630 1640 1650
TTGTTSTVTM STSSVTSSSN VATATTVLSV CQSLSNTLTT SLTSTSSESD
1660 1670 1680 1690 1700
TGQEAEYSLY DFLDSCRAST LLAELDDDED LPEPDEEDDE NEDDNQEDQE
1710 1720 1730 1740 1750
YEEVMEEEEY ETKGGRRRTW DDDYVLKRQF SALVPAFDPR PGRTNVQQTT
1760 1770 1780 1790 1800
DLEIPPPGTP HSELLEEVEC TPSPRLALTL KVTGLGTSRE VELPLTNFRS
1810 1820 1830 1840 1850
TIFYYVQKLL QLSCNGSVKT DKLRRIWEPT YTIVYREMKD SDKEKENGKM
1860 1870 1880 1890 1900
GCWSIEHVEQ YLGTDELPKN DLITYLQKNA DSAFLRHWKL TGTNKSIRKN
1910 1920 1930 1940 1950
RNCSQLIAAY KDFCEHGSKS SLNQGTISTL QNSDILSSIK EQPQAKAGSG
1960 1970 1980 1990 2000
QNSCGVEDVL QLLRILYIVA SDPYSTRTSQ EEGDEQLQFN FPPDEFTSKK
2010 2020 2030 2040 2050
ITTKILQQIE EPLALASGAL PDWCEQITSK CPFLIPFETR QLYFTCTAFG
2060 2070 2080 2090 2100
ASRAIVWLQN RREATVERTR TPSTVRRDDP GEFRVGRLKH ERVKVPRGES
2110 2120 2130 2140 2150
LMEWAENVMQ IHADRKSVLE VEFLGEEGTG LGPTLEFYAL VAAEFQRTEL
2160 2170 2180 2190 2200
GAWLCDDDFP DDESRQVDIG GGLKPPGYYV QRSCGLFTAP FPQDSDELER
2210 2220 2230 2240 2250
ITKLFHFLGI FLAKCIQDNR LVDLPISKPF FKLMCMGDIK SNMSKLIYES
2260 2270 2280 2290 2300
RGDRDLHCTE SQSEASTEEG HDSLSVGSFE EDSKSEFILD PPKPKPPAWF
2310 2320 2330 2340 2350
NGILTWEDFE LVNPHRARFL KEIKDLAIKR RQILSNKGLS EDEKNTKLQE
2360 2370 2380 2390 2400
LMMKNRSGSG PALSIEDLGL NFQFCPSSRV YGFTAVDLKP GGEDELVTMD
2410 2420 2430 2440 2450
NAEEYVDLMF DFCMHTGIQK QMDAFRDGFN RVFPMEKLSS FSHEEVQMIL
2460 2470 2480 2490 2500
CGNQSPSWAA EDIINYTEPK LGYTRDSPGF LRFVRVLCGM SSDERKAFLQ
2510 2520 2530 2540 2550
FTTGCSTLPP GGLANLHPRL TVVRKVDATD ASYPSVNTCV HYLKLPEYSS
2560 2570
EEIMRERLLA ATMEKGFHLN
Length:2,570
Mass (Da):285,354
Last modified:June 26, 2013 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA68AA92B13467E43
GO

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
XP_008101611.1, XM_008103404.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSACAT00000015164; ENSACAP00000014864; ENSACAG00000015118

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
100556040

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_008101611.1, XM_008103404.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi28377.ENSACAP00000014864

Genome annotation databases

EnsembliENSACAT00000015164; ENSACAP00000014864; ENSACAG00000015118
GeneIDi100556040

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
25831

Phylogenomic databases

eggNOGiKOG4276, Eukaryota
GeneTreeiENSGT00940000156572
HOGENOMiCLU_000869_0_0_1
InParanoidiG1KQQ3
OMAiAKQWYDL
OrthoDBi34110at2759
TreeFamiTF323674

Enzyme and pathway databases

UniPathwayiUPA00143

Gene expression databases

BgeeiENSACAG00000015118, Expressed in embryonic post-anal tail and 14 other tissues

Family and domain databases

CDDicd00078, HECTc, 1 hit
Gene3Di1.25.10.10, 1 hit
1.25.40.20, 1 hit
2.30.30.920, 1 hit
2.60.120.260, 1 hit
InterProiView protein in InterPro
IPR002110, Ankyrin_rpt
IPR020683, Ankyrin_rpt-contain_dom
IPR036770, Ankyrin_rpt-contain_sf
IPR011989, ARM-like
IPR016024, ARM-type_fold
IPR041200, FKBP3_BTHB
IPR008979, Galactose-bd-like_sf
IPR000569, HECT_dom
IPR035983, Hect_E3_ubiquitin_ligase
IPR010606, Mib_Herc2
IPR037252, Mib_Herc2_sf
IPR012919, SUN_dom
PfamiView protein in Pfam
PF12796, Ank_2, 1 hit
PF18410, BTHB, 1 hit
PF00632, HECT, 1 hit
PF06701, MIB_HERC2, 1 hit
PF07738, Sad1_UNC, 1 hit
SMARTiView protein in SMART
SM00248, ANK, 3 hits
SM00119, HECTc, 1 hit
SUPFAMiSSF159034, SSF159034, 1 hit
SSF48371, SSF48371, 1 hit
SSF48403, SSF48403, 1 hit
SSF49785, SSF49785, 1 hit
SSF56204, SSF56204, 1 hit
PROSITEiView protein in PROSITE
PS50297, ANK_REP_REGION, 1 hit
PS50088, ANK_REPEAT, 2 hits
PS50237, HECT, 1 hit
PS51416, MIB_HERC2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG1KQQ3_ANOCA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G1KQQ3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: June 26, 2013
Last modified: April 7, 2021
This is version 67 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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