Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 67 (02 Jun 2021)
Sequence version 2 (26 Jun 2013)
Previous versions | rss
Add a publicationFeedback
Protein
Submitted name:

Uncharacterized protein

Gene

SYTL5

Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SYTL5Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAnolis carolinensis (Green anole) (American chameleon)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri28377 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiLepidosauriaSquamataBifurcataUnidentataEpisquamataToxicoferaIguaniaDactyloidaeAnolis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001646 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSACAG00000014773, Expressed in testis and 10 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
28377.ENSACAP00000014552

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini7 – 126RabBDInterPro annotationAdd BLAST120
Domaini456 – 545C2InterPro annotationAdd BLAST90
Domaini623 – 712C2InterPro annotationAdd BLAST90

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni153 – 185DisorderedSequence analysisAdd BLAST33
Regioni250 – 346DisorderedSequence analysisAdd BLAST97

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili32 – 59Sequence analysisAdd BLAST28

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi153 – 171Basic and acidic residuesSequence analysisAdd BLAST19
Compositional biasi256 – 284Polar residuesSequence analysisAdd BLAST29
Compositional biasi292 – 306Polar residuesSequence analysisAdd BLAST15
Compositional biasi313 – 346Polar residuesSequence analysisAdd BLAST34

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1028, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000158618

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_002711_5_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
G1KQC2

Identification of Orthologs from Complete Genome Data

More...
OMAi
SSMRKCN

Database of Orthologous Groups

More...
OrthoDBi
916843at2759

TreeFam database of animal gene trees

More...
TreeFami
TF341184

Family and domain databases

Conserved Domains Database

More...
CDDi
cd04029, C2A_SLP-4_5, 1 hit
cd04020, C2B_SLP_1-2-3-4, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.150, 2 hits
3.30.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000008, C2_dom
IPR035892, C2_domain_sf
IPR041282, FYVE_2
IPR010911, Rab_BD
IPR037303, SLP-4/5_C2A
IPR028702, Slp5
IPR043567, SYTL1-5_C2B
IPR011011, Znf_FYVE_PHD
IPR013083, Znf_RING/FYVE/PHD

The PANTHER Classification System

More...
PANTHERi
PTHR45716:SF6, PTHR45716:SF6, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00168, C2, 2 hits
PF02318, FYVE_2, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00239, C2, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57903, SSF57903, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50004, C2, 2 hits
PS50916, RABBD, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

G1KQC2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSKNLEIINL SFLLDHERET ILGVLKRDEY LKKIEDKRIR KLQNELLEVK
60 70 80 90 100
RKGGRHQQRQ LENSRVCIRC QKNLGLIFDR GDFCPTCGLR VCSQCRVEGM
110 120 130 140 150
GGKWKCTVCD KIGHLRIVTG EWFFEERSKR FKQSKLLGTD VVRRSLLRKL
160 170 180 190 200
PGDSSEQIEG RKTKDELPGN SENTTKQDVL SSLSSGTKVV LSGPRKIGKK
210 220 230 240 250
VFKGISKGDV ANVKAEDGRS ISSDADAQSM NGAERGSILS LDGNDLEDIS
260 270 280 290 300
GSLKRGVDSR NHSSASTPVR PRSPALSTRS MTVDYSMEPG LENGTCLSTS
310 320 330 340 350
GSIPRELAKR NQGKVSRTPS IAISRTSLSS DRSRSEIDLS GSFSEGNDDT
360 370 380 390 400
LSIRSKSVPG ALDQELDYLG ETEEDIDYIM ASSSSKKRAN LASGLSTNSP
410 420 430 440 450
SSDRKWTYLN VPEADGDTTS INSMMSVYSE TGDYGNVKIS GEICLQISYS
460 470 480 490 500
YKTGALNILV KKCKNLAVVD EKKHRTDPYV KAYLLPDKSR QSKRKTKIKS
510 520 530 540 550
NTTNPEFNEM LKYVISHTQL ETRTLQLSVW HYDRFGHNSF LGEVEIPLDS
560 570 580 590 600
WNFENQADEW FVLQPKMEVA ADTGLQYKGE LVVILRYTPP ERNLTLPLGE
610 620 630 640 650
IQGKKSSKKA RKSNSQLLSG GILEVIIKEA KNLMAVKSGG TSDTFVKGYL
660 670 680 690 700
LPDNNKASKH KTHVIKKSVN PHWNHTFTFS GLNPRDIHNV CVELTVWDKE
710 720 730 740 750
SLSSNIFLGG VRLNTGSGLS NGKEVDWMDS QGEEQLLWQQ MIDCSGDSVE
760
GVLMLRSSMG KRRL
Length:764
Mass (Da):85,089
Last modified:June 26, 2013 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6735AC9CA4F84F31
GO

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
XP_008105585.1, XM_008107378.2
XP_016847916.1, XM_016992427.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSACAT00000014847; ENSACAP00000014552; ENSACAG00000014773

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
100562744

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
acs:100562744

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_008105585.1, XM_008107378.2
XP_016847916.1, XM_016992427.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi28377.ENSACAP00000014552

Genome annotation databases

EnsembliENSACAT00000014847; ENSACAP00000014552; ENSACAG00000014773
GeneIDi100562744
KEGGiacs:100562744

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
94122

Phylogenomic databases

eggNOGiKOG1028, Eukaryota
GeneTreeiENSGT00940000158618
HOGENOMiCLU_002711_5_0_1
InParanoidiG1KQC2
OMAiSSMRKCN
OrthoDBi916843at2759
TreeFamiTF341184

Gene expression databases

BgeeiENSACAG00000014773, Expressed in testis and 10 other tissues

Family and domain databases

CDDicd04029, C2A_SLP-4_5, 1 hit
cd04020, C2B_SLP_1-2-3-4, 1 hit
Gene3Di2.60.40.150, 2 hits
3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR000008, C2_dom
IPR035892, C2_domain_sf
IPR041282, FYVE_2
IPR010911, Rab_BD
IPR037303, SLP-4/5_C2A
IPR028702, Slp5
IPR043567, SYTL1-5_C2B
IPR011011, Znf_FYVE_PHD
IPR013083, Znf_RING/FYVE/PHD
PANTHERiPTHR45716:SF6, PTHR45716:SF6, 1 hit
PfamiView protein in Pfam
PF00168, C2, 2 hits
PF02318, FYVE_2, 1 hit
SMARTiView protein in SMART
SM00239, C2, 2 hits
SUPFAMiSSF57903, SSF57903, 1 hit
PROSITEiView protein in PROSITE
PS50004, C2, 2 hits
PS50916, RABBD, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG1KQC2_ANOCA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G1KQC2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: June 26, 2013
Last modified: June 2, 2021
This is version 67 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again