UniProtKB - G1KP36 (G1KP36_ANOCA)
Protein
BHLH domain-containing protein
Gene
MLX
Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Functioni
GO - Molecular functioni
- DNA-binding transcription factor activity Source: GO_Central
- DNA-binding transcription repressor activity, RNA polymerase II-specific Source: Ensembl
- protein heterodimerization activity Source: Ensembl
- protein homodimerization activity Source: Ensembl
- RNA polymerase II transcription regulatory region sequence-specific DNA binding Source: Ensembl
- transcription factor binding Source: Ensembl
GO - Biological processi
- positive regulation of transcription by RNA polymerase II Source: Ensembl
- regulation of transcription by RNA polymerase II Source: GO_Central
Names & Taxonomyi
Protein namesi | Recommended name: BHLH domain-containing proteinInterPro annotation |
Gene namesi | Name:MLXImported |
Organismi | Anolis carolinensis (Green anole) (American chameleon)Imported |
Taxonomic identifieri | 28377 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Lepidosauria › Squamata › Bifurcata › Unidentata › Episquamata › Toxicofera › Iguania › Dactyloidae › Anolis |
Proteomesi |
|
Subcellular locationi
Cytosol
- cytosol Source: Ensembl
Nucleus
- nuclear membrane Source: Ensembl
- nucleoplasm Source: Ensembl
- nucleus Source: GO_Central
Expressioni
Gene expression databases
Bgeei | ENSACAG00000013679, Expressed in dewlap and 15 other tissues |
Interactioni
GO - Molecular functioni
- protein heterodimerization activity Source: Ensembl
- protein homodimerization activity Source: Ensembl
- transcription factor binding Source: Ensembl
Protein-protein interaction databases
STRINGi | 28377.ENSACAP00000013439 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 77 – 135 | BHLHInterPro annotationAdd BLAST | 59 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 91 | DisorderedSequence analysisAdd BLAST | 91 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 132 – 159 | Sequence analysisAdd BLAST | 28 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 39 – 60 | PolarSequence analysisAdd BLAST | 22 | |
Compositional biasi | 67 – 91 | PolyampholyteSequence analysisAdd BLAST | 25 |
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
eggNOGi | KOG1319, Eukaryota |
GeneTreei | ENSGT00940000157377 |
HOGENOMi | CLU_083204_0_0_1 |
InParanoidi | G1KP36 |
OMAi | AHNTEDE |
OrthoDBi | 1234389at2759 |
TreeFami | TF318841 |
Family and domain databases
CDDi | cd00083, HLH, 1 hit |
Gene3Di | 4.10.280.10, 1 hit |
InterProi | View protein in InterPro IPR011598, bHLH_dom IPR036638, HLH_DNA-bd_sf IPR032647, Mlx |
PANTHERi | PTHR15741:SF25, PTHR15741:SF25, 1 hit |
Pfami | View protein in Pfam PF00010, HLH, 1 hit |
SMARTi | View protein in SMART SM00353, HLH, 1 hit |
SUPFAMi | SSF47459, SSF47459, 1 hit |
PROSITEi | View protein in PROSITE PS50888, BHLH, 1 hit |
i Sequence
Sequence statusi: Complete.
G1KP36-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAEPSSVSPE NAWVGKVESS FSDNGLDPAL FVESRRKGSI VSRANSIGST
60 70 80 90 100
SASSVPNTDD EDSDYQQETY KETYKDRRRR AHTQAEQKRR DAIKKGYDDL
110 120 130 140 150
QAIVPTCQHQ DFSLGSQKLS KAIVLQKTID YIQFLHKEKK KQEEEVTTLR
160 170 180 190 200
KDVMALKIMK INYEQIVKAH QDNPNEGKNQ VSDQVKFNVF QGIMDSLFQS
210 220 230 240
FNASISVTSF QELSACVFSW IEEHCKPQTL RDIVIGVLQQ LKSQLY
Genome annotation databases
Ensembli | ENSACAT00000013714; ENSACAP00000013439; ENSACAG00000013679 |
Similar proteinsi
Cross-referencesi
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 28377.ENSACAP00000013439 |
Genome annotation databases
Ensembli | ENSACAT00000013714; ENSACAP00000013439; ENSACAG00000013679 |
Phylogenomic databases
eggNOGi | KOG1319, Eukaryota |
GeneTreei | ENSGT00940000157377 |
HOGENOMi | CLU_083204_0_0_1 |
InParanoidi | G1KP36 |
OMAi | AHNTEDE |
OrthoDBi | 1234389at2759 |
TreeFami | TF318841 |
Gene expression databases
Bgeei | ENSACAG00000013679, Expressed in dewlap and 15 other tissues |
Family and domain databases
CDDi | cd00083, HLH, 1 hit |
Gene3Di | 4.10.280.10, 1 hit |
InterProi | View protein in InterPro IPR011598, bHLH_dom IPR036638, HLH_DNA-bd_sf IPR032647, Mlx |
PANTHERi | PTHR15741:SF25, PTHR15741:SF25, 1 hit |
Pfami | View protein in Pfam PF00010, HLH, 1 hit |
SMARTi | View protein in SMART SM00353, HLH, 1 hit |
SUPFAMi | SSF47459, SSF47459, 1 hit |
PROSITEi | View protein in PROSITE PS50888, BHLH, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | G1KP36_ANOCA | |
Accessioni | G1KP36Primary (citable) accession number: G1KP36 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 19, 2011 |
Last sequence update: | October 19, 2011 | |
Last modified: | August 12, 2020 | |
This is version 56 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |