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UniProtKB - G1KNP1 (G1KNP1_ANOCA)

Entry version 59 (02 Dec 2020)
Sequence version 2 (26 Jun 2013)
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Protein
Submitted name:

Uncharacterized protein

Gene

MMRN1

Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase, ProteaseARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MMRN1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAnolis carolinensis (Green anole) (American chameleon)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri28377 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Lepidosauria › Squamata › Bifurcata › Unidentata › Episquamata › Toxicofera › Iguania › Dactyloidae › Anolis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001646 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 20Sequence analysisAdd BLAST20
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500341363421 – 1200Sequence analysisAdd BLAST1180

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi1039 ↔ 1048PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationARBA annotation

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSACAG00000013371, Expressed in adrenal gland and 12 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		28377.ENSACAP00000013149

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini180 – 255EMIInterPro annotationAdd BLAST76
Domaini1013 – 1049EGF-likeInterPro annotationAdd BLAST37
Domaini1068 – 1200C1qInterPro annotationAdd BLAST133

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni99 – 124DisorderedSequence analysisAdd BLAST26
Regioni147 – 174DisorderedSequence analysisAdd BLAST28
Regioni271 – 297DisorderedSequence analysisAdd BLAST27
Regioni977 – 1007DisorderedSequence analysisAdd BLAST31

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili298 – 318Sequence analysisAdd BLAST21
Coiled coili477 – 497Sequence analysisAdd BLAST21
Coiled coili571 – 609Sequence analysisAdd BLAST39

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi149 – 173PolarSequence analysisAdd BLAST25
Compositional biasi990 – 1007PolarSequence analysisAdd BLAST18

Keywords - Domaini

Coiled coilSequence analysisARBA annotation, EGF-like domainPROSITE-ProRule annotationARBA annotation, SignalSequence analysisARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502QTYP, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT01010000222524

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_011016_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		G1KNP1

Database of Orthologous Groups

More...OrthoDBi		1205089at2759

TreeFam database of animal gene trees

More...TreeFami		TF336041

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.60.120.40, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR001073, C1q_dom
IPR000742, EGF-like_dom
IPR000152, EGF-type_Asp/Asn_hydroxyl_site
IPR011489, EMI_domain
IPR033188, MMRN1
IPR008983, Tumour_necrosis_fac-like_dom

The PANTHER Classification System

More...PANTHERi		PTHR15427:SF3, PTHR15427:SF3, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00386, C1q, 1 hit
PF07546, EMI, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00007, COMPLEMNTC1Q

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00110, C1Q, 1 hit
SM00181, EGF, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF49842, SSF49842, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00010, ASX_HYDROXYL, 1 hit
PS50871, C1Q, 1 hit
PS00022, EGF_1, 1 hit
PS01186, EGF_2, 1 hit
PS50026, EGF_3, 1 hit
PS51041, EMI, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

G1KNP1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKEVFLILVL LCLKWSSTGA NSTGMALITS VDSEMETSRP DLTLTKIKEF 
        60         70         80         90        100
VLTTPLPPAT EKSTVLQNTT QVVDEKHGSP LLVEEIQRLQ MPEATLQKTS 
       110        120        130        140        150
LNRTNPNGGN INSDSSNGKS SVLSNSTKIQ AQIIPRKGPL ERDVLKGATV 
       160        170        180        190        200
SRSSRQSGYN SISSKSNADL KKPSFETTRG KNWCAYVHTR LQPTIVVDNV 
       210        220        230        240        250
QSYASGRSKQ CSWITGPCGS SSQSRTQQAY RIKHMIVTSL EWKCCPGYSG 
       260        270        280        290        300
GTCQPKAQQD QLPTHNNQVE SNAAVNGGAP GNPPQQREQQ DPSDPAVAQK 
       310        320        330        340        350
MNEQISSQEM KLTLLQKKVD NISVVMSDVS KTLSSLEGKI NEDKGRDFQA 
       360        370        380        390        400
FLKGLKSKSI TELVQEIVKE QFKFHQNDMQ ETVAQIFKIV SGLSDDIENT 
       410        420        430        440        450
KELIKSLNVS QQKIVTDIAH RPTRVEIQEI RSEILHIEQD ISFTCDKPIK 
       460        470        480        490        500
VLQEKQRSME VALEHQSSKS NLYYESLNKS LTQMKEVHEQ LLSAEQRSDQ 
       510        520        530        540        550
NIPTAGKSVS DNLTDYMISL HEKVKKQSLM VLQLHDDLRV QDSKISNLTV 
       560        570        580        590        600
TLEIQKDTLE KECNGMLSKC RRDFEMQLKG TEENMHSLNK TLENLVFLLD 
       610        620        630        640        650
EKIDKMNEQI NDLCYDMEIL QPLIEQGVPF SSNSEDEQQI ETEAIKRKLE 
       660        670        680        690        700
NITSIVTGLN STIQELTKNQ KQFKTDAQAH NEISERQINE CFVLVEDGIN 
       710        720        730        740        750
KTLMVINDAI DSIRDNYVLK ETLSTFRNET EACCSWVETV ESVSALVPQF 
       760        770        780        790        800
RQMNESLQIL INGNHKPDFT SKIIRNPSEA SPDENIIPHA SPAHHDQSKI 
       810        820        830        840        850
SLTLQGHQQE IGHLDEKQVH PMQEHKDYEV RLQVVEAKIN KFLANNCVSV 
       860        870        880        890        900
RNVKAAATEN EKVVSGQLQM LSSRIRALEA KSIRLSLSMP LLNKTAYEAW 
       910        920        930        940        950
GLCKDVSGSI QALNASIPRM MKLAHPDTLL FQKGIEELTE SMLEVKAGVI 
       960        970        980        990       1000
LSNLTWYVDR SLADVADRIT KRLKAVPAVS KKPPPAKKMP VNTTANQAGR 
      1010       1020       1030       1040       1050
SQRNTDNTLE TGDYLSCSSS PCNNGGTCVN ERRGFVCACR YPFGGVNCST 
      1060       1070       1080       1090       1100
KMTEENAPAI DFSKGSYRYA PMVAFFASHT YGMNTPGPIR FNNLDVNYGS 
      1110       1120       1130       1140       1150
SYVPANGRFR VPYLGVYVFE YTVESSSPLL SGYLVVDGID KLAFRSENAN 
      1160       1170       1180       1190       1200
DNKYVERVIT GDALLELNYG QEVWLRLATG SIPAKYPPIT TFTGYLLYRT
Length:1,200
Mass (Da):134,112
Last modified:June 26, 2013 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i19CD2214CBDA0A8C
GO

Sequence databases

NCBI Reference Sequences

More...RefSeqi		XP_008109255.1, XM_008111048.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSACAT00000013410; ENSACAP00000013149; ENSACAG00000013371

Database of genes from NCBI RefSeq genomes

More...GeneIDi		100551936

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		acs:100551936

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_008109255.1, XM_008111048.2

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

STRINGi28377.ENSACAP00000013149

Genome annotation databases

EnsembliENSACAT00000013410; ENSACAP00000013149; ENSACAG00000013371
GeneIDi100551936
KEGGiacs:100551936

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		22915

Phylogenomic databases

eggNOGiENOG502QTYP, Eukaryota
GeneTreeiENSGT01010000222524
HOGENOMiCLU_011016_0_0_1
InParanoidiG1KNP1
OrthoDBi1205089at2759
TreeFamiTF336041

Gene expression databases

BgeeiENSACAG00000013371, Expressed in adrenal gland and 12 other tissues

Family and domain databases

Gene3Di2.60.120.40, 1 hit
InterProiView protein in InterPro
IPR001073, C1q_dom
IPR000742, EGF-like_dom
IPR000152, EGF-type_Asp/Asn_hydroxyl_site
IPR011489, EMI_domain
IPR033188, MMRN1
IPR008983, Tumour_necrosis_fac-like_dom
PANTHERiPTHR15427:SF3, PTHR15427:SF3, 1 hit
PfamiView protein in Pfam
PF00386, C1q, 1 hit
PF07546, EMI, 1 hit
PRINTSiPR00007, COMPLEMNTC1Q
SMARTiView protein in SMART
SM00110, C1Q, 1 hit
SM00181, EGF, 1 hit
SUPFAMiSSF49842, SSF49842, 1 hit
PROSITEiView protein in PROSITE
PS00010, ASX_HYDROXYL, 1 hit
PS50871, C1Q, 1 hit
PS00022, EGF_1, 1 hit
PS01186, EGF_2, 1 hit
PS50026, EGF_3, 1 hit
PS51041, EMI, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG1KNP1_ANOCA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G1KNP1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: June 26, 2013
Last modified: December 2, 2020
This is version 59 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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