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UniProtKB - G1KML7 (G1KML7_ANOCA)

Entry version 56 (07 Oct 2020)
Sequence version 2 (26 Jun 2013)
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Protein

CW-type domain-containing protein

Gene

morc3

Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
CW-type domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:morc3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAnolis carolinensis (Green anole) (American chameleon)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri28377 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Lepidosauria › Squamata › Bifurcata › Unidentata › Episquamata › Toxicofera › Iguania › Dactyloidae › Anolis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001646 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSACAG00000012615, Expressed in embryonic post-anal tail and 14 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		28377.ENSACAP00000012415

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini410 – 460CW-typeInterPro annotationAdd BLAST51

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni454 – 477DisorderedSequence analysisAdd BLAST24
Regioni516 – 556DisorderedSequence analysisAdd BLAST41

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili692 – 730Sequence analysisAdd BLAST39
Coiled coili763 – 800Sequence analysisAdd BLAST38
Coiled coili806 – 854Sequence analysisAdd BLAST49

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi516 – 534PolarSequence analysisAdd BLAST19

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysisARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1845, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000168489

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_011516_2_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		G1KML7

KEGG Orthology (KO)

More...KOi		K24135

Database of Orthologous Groups

More...OrthoDBi		193855at2759

TreeFam database of animal gene trees

More...TreeFami		TF329118

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR036890, HATPase_C_sf
IPR041006, Morc_S5
IPR011124, Znf_CW

Pfam protein domain database

More...Pfami		View protein in Pfam
PF17942, Morc6_S5, 1 hit
PF07496, zf-CW, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF55874, SSF55874, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51050, ZF_CW, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

G1KML7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAASSSSVQA QSGILLSALC PKFLHTNSTS HTWPFSAVAE LIDNAYDPDV 
        60         70         80         90        100
NAKQMWIDQT VINGNVCLIF MDNGNGMNAD KLHKMLSFGF SDKVTLNGRV 
       110        120        130        140        150
PVGLYGNGFK SGSMRLGKDA IVFTKNGEIM SVGMLSQTFL EVTKAEHVIV 
       160        170        180        190        200
PIISFNKKRQ VMNLEESAAS LRAILEHSLF PSEEELLAEL DAIIGKKGTR 
       210        220        230        240        250
IIIWNLRREK NQQTEFDFGT DKYDIRIPAD LDEATGKRGY KKQERQDQIT 
       260        270        280        290        300
PESDYSLRAY CSILYLKPRM QIIIRGQKVQ TQLVSKSLAY IERDVYRPKF 
       310        320        330        340        350
LAPRTVRITF GFNCRNKDHY GMMMYHRNRL IKAYERVGYQ LKANNMGVGV 
       360        370        380        390        400
VGIIECSFLK PTHNKQDFDY TNEYRLTIHA LGEKLNDYWN EMQAKKKDYP 
       410        420        430        440        450
LEVLAEDTQK RPDQTWVQCD SCLKWRKLPD GIHRLPEKWY CSYNPDPQFR 
       460        470        480        490        500
NCNVPEEPED DDLIPYEKTH KKKDREKLKK RLEFSQQIYN ELYLPTSSAL 
       510        520        530        540        550
PNTSPAVNER LHTDASNTPI SRSLNPSDNA PVSSPHSDHE NRFKRKLSNP 
       560        570        580        590        600
ETPLPFKITG VTSQAFENRK KNQVDDDDVI ILEENSTPKP ADIAECDIKI 
       610        620        630        640        650
VKVEGGTDIN YEIETESAPN KDACSEAKCS KGTVATQTER EQSEVKKEDV 
       660        670        680        690        700
KDNADNNLPI SKPEVTFVEP VHVLDPAFVD SDKRPNELSI KLQSTTREKE 
       710        720        730        740        750
NYQKQCDTLL KELNELKQKL VEMNDKYMKK EMCHQSTETD SILPDDELRQ 
       760        770        780        790        800
IKERSPEEVL ILYEQALNEV KQLKVQCNTL KNLKNECNKC RDNENKSEVD 
       810        820        830        840        850
DMAVQIDDLF RQLDECSVEK DQYKNEIELL EMEKNQLRLQ CEELKEEVTQ 
       860        870        880        890        900
LKASVPQVVS HSNGPVAGSL EDPVNFSDGE SLKLRSLRVN VGMLLASIMP 
       910        920        930 
DLDLQQMNYD VDVVDEILGQ VVEHMNDEIS SA
Length:932
Mass (Da):106,515
Last modified:June 26, 2013 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3A6ACA02D65F6075
GO

Sequence databases

NCBI Reference Sequences

More...RefSeqi		XP_003219065.1, XM_003219017.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSACAT00000012668; ENSACAP00000012415; ENSACAG00000012615

Database of genes from NCBI RefSeq genomes

More...GeneIDi		100563659

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		acs:100563659

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_003219065.1, XM_003219017.3

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

STRINGi28377.ENSACAP00000012415

Genome annotation databases

EnsembliENSACAT00000012668; ENSACAP00000012415; ENSACAG00000012615
GeneIDi100563659
KEGGiacs:100563659

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		23515

Phylogenomic databases

eggNOGiKOG1845, Eukaryota
GeneTreeiENSGT00940000168489
HOGENOMiCLU_011516_2_0_1
InParanoidiG1KML7
KOiK24135
OrthoDBi193855at2759
TreeFamiTF329118

Gene expression databases

BgeeiENSACAG00000012615, Expressed in embryonic post-anal tail and 14 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR036890, HATPase_C_sf
IPR041006, Morc_S5
IPR011124, Znf_CW
PfamiView protein in Pfam
PF17942, Morc6_S5, 1 hit
PF07496, zf-CW, 1 hit
SUPFAMiSSF55874, SSF55874, 1 hit
PROSITEiView protein in PROSITE
PS51050, ZF_CW, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG1KML7_ANOCA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G1KML7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: June 26, 2013
Last modified: October 7, 2020
This is version 56 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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Main funding by: National Institutes of Health

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