UniProtKB - G1KMA8 (G1KMA8_ANOCA)
Protein
Sulfotransfer_1 domain-containing protein
Gene
DSEL
Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Functioni
GO - Molecular functioni
- chondroitin-glucuronate 5-epimerase activity Source: GO_Central
- sulfotransferase activity Source: InterPro
GO - Biological processi
- chondroitin sulfate metabolic process Source: GO_Central
- dermatan sulfate metabolic process Source: GO_Central
Keywordsi
Molecular function | IsomeraseARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Sulfotransfer_1 domain-containing proteinInterPro annotation |
Gene namesi | Name:DSELImported |
Organismi | Anolis carolinensis (Green anole) (American chameleon)Imported |
Taxonomic identifieri | 28377 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Lepidosauria › Squamata › Bifurcata › Unidentata › Episquamata › Toxicofera › Iguania › Dactyloidae › Anolis |
Proteomesi |
|
Subcellular locationi
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 768 – 788 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 800 – 820 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 22 | Sequence analysisAdd BLAST | 22 | |
ChainiPRO_5003412897 | 23 – 1220 | Sulfotransfer_1 domain-containing proteinSequence analysisAdd BLAST | 1198 |
Expressioni
Gene expression databases
Bgeei | ENSACAG00000012451, Expressed in forelimb bud and 14 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 853 – 1205 | Sulfotransfer_1InterPro annotationAdd BLAST | 353 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 940 – 978 | DisorderedSequence analysisAdd BLAST | 39 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 940 – 954 | PolyampholyteSequence analysisAdd BLAST | 15 | |
Compositional biasi | 962 – 978 | PolyampholyteSequence analysisAdd BLAST | 17 |
Sequence similaritiesi
Belongs to the dermatan-sulfate isomerase family.ARBA annotation
Keywords - Domaini
SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisPhylogenomic databases
eggNOGi | ENOG502QPWZ, Eukaryota |
GeneTreei | ENSGT00390000006522 |
HOGENOMi | CLU_011348_0_0_1 |
InParanoidi | G1KMA8 |
OrthoDBi | 588663at2759 |
TreeFami | TF334118 |
Family and domain databases
Gene3Di | 1.50.10.100, 1 hit |
InterProi | View protein in InterPro IPR008929, Chondroitin_lyas IPR027417, P-loop_NTPase IPR000863, Sulfotransferase_dom |
Pfami | View protein in Pfam PF00685, Sulfotransfer_1, 1 hit |
SUPFAMi | SSF48230, SSF48230, 1 hit SSF52540, SSF52540, 1 hit |
i Sequence
Sequence statusi: Complete.
G1KMA8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MALLFTGHSL FLALAMLAVC TFEESVSNYS DWVTFTENVD QYEKQRLEDF
60 70 80 90 100
KADQKMKRTI PHPSLYFSAE EVPALRQKSH TSHLHLFRAI RSAVSVMLSN
110 120 130 140 150
PSYYLPPLKH ADFAAKWNEI YGNNLPPLAF YCLLCPEDKA AFEFVLEYMD
160 170 180 190 200
RLAGYKDWLV ENAPGDEVPL GHSLTGFATA FDFLYSTLDD DRRQNYLAKI
210 220 230 240 250
LAVSEEMYEY SKVRSWGKQL LHNHQATNMV ALLIGALVTE GGIEAQANIW
260 270 280 290 300
KHTVVDVMEK TMFLLNHIVD GSLDEGVAYG SYTSKSITQY IFLAQRHFGI
310 320 330 340 350
NNFENHWLKM HFWFYYATLL PGFQRTVGIA DSNYNWFYGP ESQLVFLDRF
360 370 380 390 400
VLKNGIGNWL AQQIRKHRPK DGPMVPSTAQ RWSTLHTEYL WYDPGLTPHP
410 420 430 440 450
PPDYGSAKMH VFPNWGVVTY GAGLPYGQTN TFVSFKSGKL GGRAVYDIVH
460 470 480 490 500
FQPYSWIDGW RSFNPGHEHP DQNSFTFAPN GQVFVSEALY GPKLSHLNNV
510 520 530 540 550
LVFAPSPTSQ CNQPWEGQLG ECTQWLKWTG DEVGDAAGEI ITSSQHEDMM
560 570 580 590 600
FVSGEAASTY SSAMKLKSVY RSLLLLNHQT LLVVDHVEKE VDSPINSISA
610 620 630 640 650
FFHNLDIDFK YVPYKFMNKY NGAMMDVWDA HYKMFWFDHH GSSPVARIQE
660 670 680 690 700
AEQAAEFKKR WTQFVNVTFS AKSTTARIAY VFYGPYVNVS SCRFVDDAQA
710 720 730 740 750
GFRISLNVNN TETVFSVVTD YLNLGTRFNY LGFGGYAKVT TQGKVTRFGL
760 770 780 790 800
GTEAVKKQAL NNKTVFPFGF KVNIIAGLIL GISLVILAIQ WRFYISFGKL
810 820 830 840 850
LRWTLILVIL LWFVELIDVW SSCTQPICAK WSSDVASTEG NAEKDQGHPV
860 870 880 890 900
TLPDIVITSL PNSGAEILKQ LFFNSSDFIY IRIPTGYLDV PETEFEIDSF
910 920 930 940 950
VDACEWKASD VQSGHFRLLQ GWLHSLVKDT KLHLQNIHLH EPSRSKSAQH
960 970 980 990 1000
PSPSKDKKRR PRKRESIAEQ RTRLRGSSDK EAEYIRDLRR HLAFYPNARP
1010 1020 1030 1040 1050
VLSLSSGSWT LKLPFFQEII GLSLRALYVV RDPRAWVHSI LYKSQPSLYS
1060 1070 1080 1090 1100
LRKVPQRLAR LFKPDGKRKD KCHLNSGYAL EYEPLREELS HSNSNAVSVM
1110 1120 1130 1140 1150
SHLWLANTAA ALRLNGDLLP ANYRLLKFED IVNFPHKVAE AVYAFLGIPL
1160 1170 1180 1190 1200
SPASLNQILF ATSTNLFYLP YEGEVSPVSI HAWRHDLPLE EIKLIEDICS
1210 1220
TLMDRLGYPK FTDLDAAGQQ
Sequence databases
RefSeqi | XP_003219769.2, XM_003219721.3 |
Genome annotation databases
Ensembli | ENSACAT00000012439; ENSACAP00000012191; ENSACAG00000012451 |
GeneIDi | 100556705 |
KEGGi | acs:100556705 |
Similar proteinsi
Cross-referencesi
Sequence databases
RefSeqi | XP_003219769.2, XM_003219721.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 28377.ENSACAP00000012191 |
Genome annotation databases
Ensembli | ENSACAT00000012439; ENSACAP00000012191; ENSACAG00000012451 |
GeneIDi | 100556705 |
KEGGi | acs:100556705 |
Organism-specific databases
CTDi | 92126 |
Phylogenomic databases
eggNOGi | ENOG502QPWZ, Eukaryota |
GeneTreei | ENSGT00390000006522 |
HOGENOMi | CLU_011348_0_0_1 |
InParanoidi | G1KMA8 |
OrthoDBi | 588663at2759 |
TreeFami | TF334118 |
Gene expression databases
Bgeei | ENSACAG00000012451, Expressed in forelimb bud and 14 other tissues |
Family and domain databases
Gene3Di | 1.50.10.100, 1 hit |
InterProi | View protein in InterPro IPR008929, Chondroitin_lyas IPR027417, P-loop_NTPase IPR000863, Sulfotransferase_dom |
Pfami | View protein in Pfam PF00685, Sulfotransfer_1, 1 hit |
SUPFAMi | SSF48230, SSF48230, 1 hit SSF52540, SSF52540, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | G1KMA8_ANOCA | |
Accessioni | G1KMA8Primary (citable) accession number: G1KMA8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 19, 2011 |
Last sequence update: | June 26, 2013 | |
Last modified: | October 7, 2020 | |
This is version 53 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |