UniProtKB - G1KM60 (G1KM60_ANOCA)
Protein
BTB domain-containing protein
Gene
KLHL8
Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Functioni
GO - Biological processi
- protein ubiquitination Source: Ensembl
- ubiquitin-dependent protein catabolic process Source: Ensembl
Names & Taxonomyi
Protein namesi | Recommended name: BTB domain-containing proteinInterPro annotation |
Gene namesi | Name:KLHL8Imported |
Organismi | Anolis carolinensis (Green anole) (American chameleon)Imported |
Taxonomic identifieri | 28377 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Lepidosauria › Squamata › Bifurcata › Unidentata › Episquamata › Toxicofera › Iguania › Dactyloidae › Anolis |
Proteomesi |
|
Subcellular locationi
Nucleus
- nucleoplasm Source: Ensembl
Other locations
- Cul3-RING ubiquitin ligase complex Source: Ensembl
Expressioni
Gene expression databases
Bgeei | ENSACAG00000012252, Expressed in dewlap and 14 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 63 – 130 | BTBInterPro annotationAdd BLAST | 68 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 29 | DisorderedSequence analysisAdd BLAST | 29 |
Keywords - Domaini
Kelch repeatARBA annotation, RepeatARBA annotationPhylogenomic databases
eggNOGi | KOG4441, Eukaryota |
GeneTreei | ENSGT00940000157583 |
HOGENOMi | CLU_004253_14_2_1 |
InParanoidi | G1KM60 |
TreeFami | TF329218 |
Family and domain databases
Gene3Di | 2.120.10.80, 2 hits |
InterProi | View protein in InterPro IPR011705, BACK IPR017096, BTB-kelch_protein IPR000210, BTB/POZ_dom IPR015915, Kelch-typ_b-propeller IPR006652, Kelch_1 IPR030605, KLHL8 IPR011333, SKP1/BTB/POZ_sf |
PANTHERi | PTHR24412:SF403, PTHR24412:SF403, 1 hit |
Pfami | View protein in Pfam PF07707, BACK, 1 hit PF00651, BTB, 1 hit PF01344, Kelch_1, 6 hits |
PIRSFi | PIRSF037037, Kelch-like_protein_gigaxonin, 3 hits |
SMARTi | View protein in SMART SM00875, BACK, 1 hit SM00225, BTB, 1 hit SM00612, Kelch, 6 hits |
SUPFAMi | SSF117281, SSF117281, 2 hits SSF54695, SSF54695, 1 hit |
PROSITEi | View protein in PROSITE PS50097, BTB, 1 hit |
i Sequence
Sequence statusi: Complete.
G1KM60-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MASDCMVPEQ AKHRVVKGKR QQQYERSPLN SDAEEETFVF EANEAWKDFH
60 70 80 90 100
SSLLHFYEAG ELCDVTLKVG SKLISLSQAC ACLCYSLLPT MFLSEIAEAK
110 120 130 140 150
QSLIEIKDFD GDAIEDLVKF VYSSRLTLTV DNVQPLLYAA CILQVEVVAK
160 170 180 190 200
ACCEYMKLHF HPSNCLAVRA FAESHNRVDL MDMADRYACE HFAEVVECED
210 220 230 240 250
FVSVSPQHLH KLLSSNDLSI ESEKQVYRAA IKWLLANPQH HTTWLDEIIA
260 270 280 290 300
QVRLPLLPIC FLMGVVAKEE IVKQNLKCRD LLDEARNYHL HLSSHTVPDF
310 320 330 340 350
EYSVRTTPRK HTAGVLFCVG GRGGSGDPFR SIECYSVNNN SWFFGPEMNS
360 370 380 390 400
RRRHVGVISV GGKVYAVGGH DGNEHLGSME MFDPLSNKWM MKASMNTKRR
410 420 430 440 450
GIALASLGGP IYAIGGLDDN TCFSEVERYD IESDQWSGVA PMNTPRGGVG
460 470 480 490 500
SVALMNYVYA VGGNDGVASL SSVEKYDPYL DKWIEVKEMG QRRAGNGVSE
510 520 530 540 550
LHGCLYVVGG FDDNSPLSSV ERFDPRSGSK WEYVAELTTP RGGVGIATLM
560 570 580 590 600
GKIFAVGGHN GNAYLNTVEA YDPVANRWEL VGSVSHCRAG AGVAVCACLS
610
SQIRDMGHGS SNVVDCM
Genome annotation databases
Ensembli | ENSACAT00000012345; ENSACAP00000012100; ENSACAG00000012252 |
Similar proteinsi
Cross-referencesi
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 28377.ENSACAP00000012100 |
Genome annotation databases
Ensembli | ENSACAT00000012345; ENSACAP00000012100; ENSACAG00000012252 |
Phylogenomic databases
eggNOGi | KOG4441, Eukaryota |
GeneTreei | ENSGT00940000157583 |
HOGENOMi | CLU_004253_14_2_1 |
InParanoidi | G1KM60 |
TreeFami | TF329218 |
Gene expression databases
Bgeei | ENSACAG00000012252, Expressed in dewlap and 14 other tissues |
Family and domain databases
Gene3Di | 2.120.10.80, 2 hits |
InterProi | View protein in InterPro IPR011705, BACK IPR017096, BTB-kelch_protein IPR000210, BTB/POZ_dom IPR015915, Kelch-typ_b-propeller IPR006652, Kelch_1 IPR030605, KLHL8 IPR011333, SKP1/BTB/POZ_sf |
PANTHERi | PTHR24412:SF403, PTHR24412:SF403, 1 hit |
Pfami | View protein in Pfam PF07707, BACK, 1 hit PF00651, BTB, 1 hit PF01344, Kelch_1, 6 hits |
PIRSFi | PIRSF037037, Kelch-like_protein_gigaxonin, 3 hits |
SMARTi | View protein in SMART SM00875, BACK, 1 hit SM00225, BTB, 1 hit SM00612, Kelch, 6 hits |
SUPFAMi | SSF117281, SSF117281, 2 hits SSF54695, SSF54695, 1 hit |
PROSITEi | View protein in PROSITE PS50097, BTB, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | G1KM60_ANOCA | |
Accessioni | G1KM60Primary (citable) accession number: G1KM60 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 19, 2011 |
Last sequence update: | June 26, 2013 | |
Last modified: | August 12, 2020 | |
This is version 59 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |