UniProtKB - G1KL88 (G1KL88_ANOCA)
Protein
Bromo domain-containing protein
Gene
ATAD2B
Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Functioni
GO - Molecular functioni
- ATPase activity Source: GO_Central
- ATP binding Source: InterPro
- chromatin binding Source: GO_Central
- histone binding Source: GO_Central
- lysine-acetylated histone binding Source: Ensembl
GO - Biological processi
- negative regulation of chromatin silencing Source: GO_Central
- positive regulation of transcription by RNA polymerase II Source: GO_Central
Names & Taxonomyi
Protein namesi | Recommended name: Bromo domain-containing proteinInterPro annotation |
Gene namesi | Name:ATAD2BImported |
Organismi | Anolis carolinensis (Green anole) (American chameleon)Imported |
Taxonomic identifieri | 28377 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Lepidosauria › Squamata › Bifurcata › Unidentata › Episquamata › Toxicofera › Iguania › Dactyloidae › Anolis |
Proteomesi |
|
Subcellular locationi
Nucleus
- nucleoplasm Source: Ensembl
- nucleus Source: GO_Central
Expressioni
Gene expression databases
Bgeei | ENSACAG00000011448, Expressed in forelimb bud and 14 other tissues |
Interactioni
GO - Molecular functioni
- histone binding Source: GO_Central
- lysine-acetylated histone binding Source: Ensembl
Protein-protein interaction databases
STRINGi | 28377.ENSACAP00000011317 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 966 – 1029 | BromoInterPro annotationAdd BLAST | 64 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 131 | DisorderedSequence analysisAdd BLAST | 131 | |
Regioni | 235 – 281 | DisorderedSequence analysisAdd BLAST | 47 | |
Regioni | 312 – 344 | DisorderedSequence analysisAdd BLAST | 33 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 933 – 960 | Sequence analysisAdd BLAST | 28 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 80 – 102 | PolyampholyteSequence analysisAdd BLAST | 23 | |
Compositional biasi | 103 – 131 | PolarSequence analysisAdd BLAST | 29 | |
Compositional biasi | 250 – 269 | AcidicSequence analysisAdd BLAST | 20 | |
Compositional biasi | 323 – 341 | PolyampholyteSequence analysisAdd BLAST | 19 |
Keywords - Domaini
BromodomainPROSITE-ProRule annotationARBA annotation, Coiled coilSequence analysisPhylogenomic databases
eggNOGi | KOG0732, Eukaryota |
GeneTreei | ENSGT00550000074694 |
HOGENOMi | CLU_001448_3_0_1 |
InParanoidi | G1KL88 |
TreeFami | TF314783 |
Family and domain databases
Gene3Di | 1.20.920.10, 1 hit |
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR041569, AAA_lid_3 IPR003959, ATPase_AAA_core IPR003960, ATPase_AAA_CS IPR001487, Bromodomain IPR036427, Bromodomain-like_sf IPR018359, Bromodomain_CS IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00004, AAA, 1 hit PF17862, AAA_lid_3, 1 hit PF00439, Bromodomain, 1 hit |
PRINTSi | PR00503, BROMODOMAIN |
SMARTi | View protein in SMART SM00382, AAA, 1 hit SM00297, BROMO, 1 hit |
SUPFAMi | SSF47370, SSF47370, 1 hit SSF52540, SSF52540, 2 hits |
PROSITEi | View protein in PROSITE PS00674, AAA, 1 hit PS00633, BROMODOMAIN_1, 1 hit PS50014, BROMODOMAIN_2, 1 hit |
i Sequence
Sequence statusi: Complete.
G1KL88-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MVNTRKSAQS QRLLGKAAGS GPGSHFISSR TRLSRTSAKA AAAAAEAALA
60 70 80 90 100
AGAAAGQEDD SARRDDGSDG SLSDSHISPP AKRTLKHADS VCKDKSKSRS
110 120 130 140 150
TGQREEWSVS TGQSRLNSQS GATLPNGRSL SLKSCSLRGE KKGDGDHACI
160 170 180 190 200
NGGREIRKSC RSRKNRFESL NQSLLFDQLV NSTAEAVLQE MDNINIRRNR
210 220 230 240 250
RSGEVERLRM WTDTEFENMD MYSRVKRRRK SLRRNSYGIQ NHHEVSTEGE
260 270 280 290 300
EEESQEEDGD IEAEEAEGEE NDRPYNLRQR KTVERYQAPP IVPAHQKKRE
310 320 330 340 350
NTLFDIHRSP ARRSHIRRKK HAIHSSDTTS SDEERFERRK SKSMARARNR
360 370 380 390 400
CLPMNFRAED LASGILRERV KVGASLADVD PMILDKSVRF DSIGGLSNHI
410 420 430 440 450
HALKEMVIFP LLYPEIFEKF KIQPPRGCLF YGPPGTGKTL VARALANECT
460 470 480 490 500
EGERKVAFFM RKGADCLSKW VGESERQLRL LFDQAYLMRP SIIFFDEIDG
510 520 530 540 550
LAPVRSSRQD QIHSSIVSTL LALMDGLDNR GEIVVIGATN RLDSIDPALR
560 570 580 590 600
RPGRFDREFL FSLPDQKARK HILQIHTRSW NPRLSDHFLE ELAEKCVGYC
610 620 630 640 650
GADIKALCTE AALIALRRRY PQIYASSQKL QLDVASIVLS AQDFYHAMQN
660 670 680 690 700
IVPASQRAVM SSGHALSPIV RPLLERTFND ILAVLRRVFP HAEISQSDKK
710 720 730 740 750
EDATNLILDD SEDENASSIF EISCPLGSPK KQLSAAINNK PYLHFTMSAY
760 770 780 790 800
HQSTSYRPRL LLSGERDSGQ TSHLAPAVLH SLEKIAVHRL DLPALYSVSA
810 820 830 840 850
KTPEESCAQI FREARRTLPS IVYMPHIGDW WEAVSETVKA TFLTLLQDIP
860 870 880 890 900
SFSPIFLLST SETMYSELPE EVKCIFKIQY EEVFYIQRPS EEDRRKFFEE
910 920 930 940 950
LVLNQASMPP PRRKQTALSD LEVLPLALPS PTHQLSEAEK QRLEDQEENT
960 970 980 990 1000
LRELRLFLRD VTKRLATDKR FNIFSKPVDI EEVSDYLEVI KEPMDLSTII
1010 1020 1030 1040 1050
TKIDKHNYLT TKDFLIDIDL ICSNALEYNP DKEPGDKIIR HRACTLKDTA
1060 1070 1080 1090 1100
HAIIAAELDP EFNKMCEEIK EARKKRGLSV TAEQINPHGS NVQKAETRVE
1110 1120
EAFQNKQKNA MTLWRSSANK CACKCLR
Genome annotation databases
Ensembli | ENSACAT00000011555; ENSACAP00000011317; ENSACAG00000011448 |
Similar proteinsi
Cross-referencesi
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 28377.ENSACAP00000011317 |
Genome annotation databases
Ensembli | ENSACAT00000011555; ENSACAP00000011317; ENSACAG00000011448 |
Phylogenomic databases
eggNOGi | KOG0732, Eukaryota |
GeneTreei | ENSGT00550000074694 |
HOGENOMi | CLU_001448_3_0_1 |
InParanoidi | G1KL88 |
TreeFami | TF314783 |
Gene expression databases
Bgeei | ENSACAG00000011448, Expressed in forelimb bud and 14 other tissues |
Family and domain databases
Gene3Di | 1.20.920.10, 1 hit |
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR041569, AAA_lid_3 IPR003959, ATPase_AAA_core IPR003960, ATPase_AAA_CS IPR001487, Bromodomain IPR036427, Bromodomain-like_sf IPR018359, Bromodomain_CS IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00004, AAA, 1 hit PF17862, AAA_lid_3, 1 hit PF00439, Bromodomain, 1 hit |
PRINTSi | PR00503, BROMODOMAIN |
SMARTi | View protein in SMART SM00382, AAA, 1 hit SM00297, BROMO, 1 hit |
SUPFAMi | SSF47370, SSF47370, 1 hit SSF52540, SSF52540, 2 hits |
PROSITEi | View protein in PROSITE PS00674, AAA, 1 hit PS00633, BROMODOMAIN_1, 1 hit PS50014, BROMODOMAIN_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | G1KL88_ANOCA | |
Accessioni | G1KL88Primary (citable) accession number: G1KL88 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 19, 2011 |
Last sequence update: | June 26, 2013 | |
Last modified: | August 12, 2020 | |
This is version 58 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |